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Home > Biochemical Engineering > Polypeptide > MOTS-c for Sale > MOTS-C Mitochondrial-derived peptide Activates AMPK pathway to boost glucose uptake
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MOTS-C Mitochondrial-derived peptide Activates AMPK pathway to boost glucose uptake

136 Inquiries

Unit Price:

$8-9/G FOB

Get Latest Price
CAS No.:

1627580-64-6

Grade:

Pharmaceutical Grade

Content:

99%

Port:

ShenZhen

Brand:

No Brand

Packaging:

5mg 10mg 15mg 20mg 30mg 40mg 60mg 1g

Price valid (until):

2026-10-15

Company Type:
Trader
Location:
China
Payment Terms:
TT against copy of documents,100% TT in advance
Qualification:
Main Products:

Peptides,Tirzepatide,Retatrutide,GLP-1,Semaglutide,AMK-CU

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    FAQ

    Q1: Can I place a trial order for one vial?
    A: Yes, trial orders are acceptable.

    Q2: What payment terms do you support?
    A: We accept T/T, PayPal, bank transfer and other payment methods. Please pick the one most convenient for you.

    Q3: What is the lead time and shipping option?
    A: We ship by international couriers (DHL, UPS, FedEx) or air freight. Delivery time to your address is approximately 8‑10 business days.


    whatsapp:+852 56087991

    Shop Semaglutide peptide Promotes insulin secretion to control blood glucose for type 2 diabetes-Detailed Image 1 Shop Semaglutide peptide Promotes insulin secretion to control blood glucose for type 2 diabetes-Detailed Image 2 Shop Semaglutide peptide Promotes insulin secretion to control blood glucose for type 2 diabetes-Detailed Image 3


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    •  Ordering Information

      Standard specifications listed in the catalog are available in stock. For special specifications and batch requirements, please contact our sales team to confirm lead time.

    • Batch traceability: Each batch is assigned a unique batch number. Full COA is available, including purity, molecular weight and sequence verification results. 

    • Custom synthesis: We support sequence modifications (acetylation, amidation, fatty acid modification, etc.), fluorescent / biotin labeling, stable isotope labeling and impurity profile control. • Technical support: Technical consultation and literature support are provided, covering reconstitution, storage and experimental protocol design. 

    • Packaging & Shipping: Standard cold‑chain shipping is offered. Aliquot service is available upon lab request to avoid repeated freeze‑thaw cycles. 

    • Customer scope: Products are only supplied to universities, research institutes, hospital laboratories and biomedical enterprises with R&D qualifications.

    • Quality assurance: All products undergo strict quality testing before delivery. Any quality complaints supported by valid test data will be handled promptly.  Order adjustment: Notify our sales team at least 3 working days in advance if you need to modify or cancel confirmed orders. Changes after shipment cannot be accepted.

    • Payment terms: Multiple payment options are available for qualified customers. Extended credit terms can be discussed based on long-term cooperation. 

    • Confidentiality: Custom synthesis projects and your research information will be kept strictly confidential and will not be disclosed to any third parties.

    • After-sales service: Our technical team remains accessible after delivery to solve problems encountered during sample preparation and experiments.

     Product Name Retatrutide Powder
    Name Retatrutide
    Type Lyophilized Powder
    storage Store in a cool and dark place
    CAS No 2381089-83-2 
    Purity ≥99%
    Specific 5mg 10mg 15mg 20mg 30mg 40mg 60mg 1g
    Package 10 vials/box

    Product Features

    • High Purity: Manufactured by solid-phase peptide synthesis. HPLC purity ≥99%. Each batch is fully tested and verified.
    • Complete Batch Traceability: Every lot is assigned a unique batch number. Full COA documents are provided, including HPLC purity report, mass spectrometry molecular weight identification and sequence verification data.
    • Reliable Peptide Modification: Optimized fatty acid side-chain modification extends the half-life, supporting research on long-acting metabolic regulation.
    • Research Use Only: This product is strictly for laboratory research purposes, not for human or animal clinical treatment.
    • Mechanism of Action

      Retatrutide activates three key metabolic receptors simultaneously. It suppresses appetite and reduces food intake via GLP‑1 and GIP pathways, while GCGR activation elevates energy consumption. The combined triple-pathway effect delivers superior weight-lowering and glucose-controlling effects compared with dual receptor agonists. Its regulatory mode mimics the body’s natural metabolic hormone balance. In clinical research, gastrointestinal reactions are common adverse responses. The safety profile needs to be evaluated according to research data.

      Research Application

      Suitable for in vitro cell assays, in vivo animal model studies, mechanism exploration of obesity, type 2 diabetes, lipid disorders and related metabolic disorders. Widely used in university labs, research institutes, hospital research centers and biomedical R&D enterprises.

      Specifications & Packaging

      • Item: Retatrutide
      • Available strength: 10mg/vial (custom concentrations and packaging available)
      • Form: Lyophilized powder
      • Storage: Long-term storage at -20℃, avoid repeated freeze-thaw.
      • Shipping: Cold chain transportation. Aliquot service is available upon request to prevent sample degradation caused by multiple freeze-thaw cycles.


    ECHEMI Editorial Reference

    MOTS-c is a 16-amino-acid mitochondria-derived peptide encoded by a short open reading frame within the mitochondrial 12S rRNA region. It is associated with the folate-AICAR-AMPK signaling pathway and has been studied for its role in cellular metabolic regulation. As a peptide research and pharmaceutical raw material, MOTS-c is suitable for biochemical research, analytical studies, and pharmaceutical development.


    MOTS-C Synthetic is a single, non-glycosylated polypeptide chain containing 16 amino acids, having a molecular mass of 2174.59 Dalton and a Molecular formula of C10H152N280O22 S2.

    Basic Info
    Product Name:

    MOTS-c

    Other Name:

    MOTS-c;L-Arginine, L-methionyl-L-arginyl-L-tryptophyl-L-glutaminyl-L-α-glutamyl-L-methionylglycyl-L-tyrosyl-L-isoleucyl-L-phenylalanyl-L-tyrosyl-L-prolyl-L-arginyl-L-lysyl-L-leucyl-;MOTS-C acetate;Cosmetic Peptide Mots-C;MOTS-c POWDER;MOTS-c peptide;MOTS-c 5mg/10mg;H-Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg-OH

    CAS No.:

    1627580-64-6

    Molecular Formula:

    C101H152N28O22S2

    InChIKeys:

    WYTHCOXVWRKRAH-JIJBDQHHNA-N

    Molecular Weight:

    2174.62

    Exact Mass:

    2174.1110958

    EC Number:

    200-001-8

    Color/Form:

    Solid lyophilized powder

    Categories:

    Polypeptide

    Characteristics
    Density:

    1.44±0.1 g/cm3(Predicted)

    Critical Temperature & Pressure:

    Store at -20°C

    Research
    Class:

    Mitochondrial-derived peptide (MDP), 16-amino-acid peptide

    Status:

    Research compound — Not FDA approved

    Mechanism:

    MOTS-c (mitochondrial ORF of the twelve S rRNA-c) is a 16-amino-acid peptide encoded by the mitochondrial genome (not nuclear DNA). It is a mitochondrial-derived peptide that regulates metabolic homeostasis by activating the AMPK/PGC-1\u03b1 pathway, improving insulin sensitivity, and enhancing exercise capacity. MOTS-c crosses the blood-brain barrier and has been shown to reduce body weight and improve glucose tolerance in preclinical models.

    Activity note:

    MOTS-c does not act via a traditional receptor. It functions as a metabolic regulator, activating AMPK. Functional effects are observed at micromolar concentrations in cell-based assays.

    Source:

    Lee C, et al. Cell Metab. 2015;21(3):443-454. MCE: MOTS-c (CAS 1627580-64-6).DOI

    References
    PubChem:

    PubChem

    Disclaimer:

    MOTS-c is NOT FDA-approved or EMA-approved. It is a research compound only. All data are from preclinical (cell/animal) studies; no human clinical trials have been completed. This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Peptides,Tirzepatide,Retatrutide,GLP-1,Semaglutide,AMK-CU

    Location:

    18 Linchang, Wujin district, Changzhou, China

    Payment Terms:

    TT against copy of documents,100% TT in advance

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    51-100

    Year of Establishment:

    2026

    Company Profile

    HANGZHOU PLANOVO BIOTECH CO LTD. was officially established on August 25, 2016, at Linchang Group, Mandun Village, Jiaze Town, Wujin District, Changzhou, Jiangsu Province, China. As an innovative enterprise dedicated to the biotechnology sector, the company has quickly made its mark in the industry through outstanding R&D capabilities, rigorous quality control, and a diversified business portfolio, guided by its corporate philosophy of "Quality First, Customer Supreme, Innovation-driven, Integrity in Service."

    Business Scope

    The company's business covers a wide range of areas:

    • Biotechnology and Medical Device R&D Consulting: Focusing on frontier biotechnology research and driving the translation of scientific achievements into practical applications;

    • Cosmetics Production and Sales: Offering high-quality cosmetic products built on a mature R&D and manufacturing system;

    • Medical Device Manufacturing and Sales: Covering Class I, Class II, and Class III medical devices, strictly in accordance with the approved scope of relevant licenses.

    R&D Strength

    The company has an R&D team composed of senior researchers and professional technical talents who uphold the spirit of innovation and focus on R&D and consulting services in biotechnology and medical device technology. The team continuously explores cutting-edge technologies, dedicated to converting the latest scientific research results into practical applications and providing a steady stream of momentum for product innovation.

    Main Product: Tirzepatide/Retatrutide/Semaglutide/CBL-514/Peptide/GLP-1/GHK-CU/NAD+

  • Inquiry History
    136 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Mots-C CAS 1627580-64-6

    5 G Apr 26, 2026
    United States

    Bodygrowth Peptides CAS 1627580-64-6 MOTS-c (Human) Acetate peptides powder

    1 G Feb 23, 2026
    United States

    MOTS-c (Human) Acetate peptides powder

    1 G Mar 12, 2026
    Brazil

    MOTS-c 10mg Peptide Raw Material High Purity

    10 PCS Feb 17, 2026
    United States

    Mots-C

    1 KG Sep 12, 2025
    United States

    MOTS-c

    1 G Sep 11, 2026
    Hongkong, China

    MOTS-C

    1 KG Aug 17, 2026
    United States

    mots-c

    40 MG Aug 5, 2026
    United States

    Mots-c

    5 G Aug 3, 2026
    United States

    MOTS-c

    15 MG Jul 14, 2026
    Netherlands

    Mots-C 20mg

    40 MT Jul 8, 2026
    United States

    Mots-c

    1 G Jun 11, 2026
    Australia

    Mots-C

    1 KG Jun 9, 2026
    United States

    Mots-c 40mg

    10 PCS May 20, 2026
    United States

    Mots-c

    100 G May 19, 2026
    United States

    Mots-c

    1000 MG May 3, 2026
    United States

    MOTS-C

    400 MG May 1, 2026
    United States

    Mots-c

    1 G Apr 24, 2026
    United States

    Mots-c

    1000 KG Apr 24, 2026
    United States

    Mots-c

    20 PCS Apr 22, 2026
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