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Home > Biochemical Engineering > Inhibitors > 2-Propenoic acid, 3-[1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-1H-pyrrolo[2,3-b]pyridin-3-yl]-2-cyano-, (2E)- for Sale > 99% Purity PP405 (JXL069) CAS 2260696-63-5 Ru58841, Ky19382, Way316606, Erdafitinib Wholesale Price
99% Purity PP405 (JXL069) CAS 2260696-63-5 Ru58841, Ky19382, Way316606, Erdafitinib Wholesale Price buy - large image1
99% Purity PP405 (JXL069) CAS 2260696-63-5 Ru58841, Ky19382, Way316606, Erdafitinib Wholesale Price buy - image1
99% Purity PP405 (JXL069) CAS 2260696-63-5 Ru58841, Ky19382, Way316606, Erdafitinib Wholesale Price buy - image2
99% Purity PP405 (JXL069) CAS 2260696-63-5 Ru58841, Ky19382, Way316606, Erdafitinib Wholesale Price buy - image3
99% Purity PP405 (JXL069) CAS 2260696-63-5 Ru58841, Ky19382, Way316606, Erdafitinib Wholesale Price buy - image4
99% Purity PP405 (JXL069) CAS 2260696-63-5 Ru58841, Ky19382, Way316606, Erdafitinib Wholesale Price buy - image5
99% Purity PP405 (JXL069) CAS 2260696-63-5 Ru58841, Ky19382, Way316606, Erdafitinib Wholesale Price buy - image6

99% Purity PP405 (JXL069) CAS 2260696-63-5 Ru58841, Ky19382, Way316606, Erdafitinib Wholesale Price

39 Inquiries

Unit Price: Get Latest Price
CAS No.:

2260696-63-5

Grade:

Industrial Grade

Content:

99%

Port:

Qingdao

Brand:

Guozhao

Packaging:

25kg/Drum

Sample Available:

Yes

Price valid (until):

2026-10-16

Company Type:
Distributor
Location:
China
Qualification:
Main Products:

CHEMICALS

  • Product Details

  • Seller Information

  • Inquiry History

  • Description

    Product Description

    This high‑purity small‑molecule reference compound is off‑white solid powder. The product is only intended for laboratory scientific research, biochemical mechanism research and analytical testing purposes. Not for human administration, injection, clinical trials or pharmaceutical manufacturing. Synthesized and purified under strict process conditions. Each batch is tested by HPLC to confirm high purity and consistent batch‑to‑batch performance. Suitable for preparing stock solutions in laboratory solvent systems. Keep container tightly sealed, store at 2‑8℃, avoid light and moisture to prevent sample degradation.

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    Product Name JXL-069
    CAS NO. 2260696-63-5 
    Other name PP405 
    Appearance Powder
    Purity 98% HPLC 
    Application massive health
    Shelf Life  24 Months
    Storage Store at a temperature of 2-8 degrees, protected from light.

    Packaging & Shipping

    Shop 99% Purity PP405 (JXL069) CAS 2260696-63-5 Ru58841, Ky19382, Way316606, Erdafitinib Wholesale Price-Detailed Image 3

    Shop Anhydrous Betaine Powder Trimethylglycine Food Feed Cosmetic Grade 107-43-7-Detailed Image 6

    Company Profile

    We are committed to providing customers with cost-effective plastic raw materials. Our factory has good working environment, complete supporting facilities and sufficient production capacity. We own advanced production technology and professional technical team. Our sales volume has maintained steady growth since establishment. We adhere to the business philosophy of "quality guaranteed, competitive price, customer first". We strive to provide sufficient supply and stable reliable product quality for customers. Business Philosophy: Integrity-oriented, win-win cooperation Enterprise Spirit: Trust, gratitude, equality and mutual respect Enterprise Mission: Create opportunities for employees, create value for customers, and assume social responsibility Corporate Values: Exceed customer expectations, foster team spirit, enhance employee value, and undertake social responsibility. We sincerely welcome global new & existing clients to cooperate with us! Our experienced team offers 24/7 support to ensure smooth communication and prompt problem-solving. Let's grow and thrive together in internationalShop 99% Purity PP405 (JXL069) CAS 2260696-63-5 Ru58841, Ky19382, Way316606, Erdafitinib Wholesale Price-Detailed Image 5 Shop 99% Purity PP405 (JXL069) CAS 2260696-63-5 Ru58841, Ky19382, Way316606, Erdafitinib Wholesale Price-Detailed Image 6 Shop 99% Purity PP405 (JXL069) CAS 2260696-63-5 Ru58841, Ky19382, Way316606, Erdafitinib Wholesale Price-Detailed Image 7

    FAQ

    1.Are you a factory or trading company
    We are a company integrating manufacturer and trading company

    2.How is the quality I want to test.
    Before production and extraction, we will test all raw materials.Quality is our top priority. All products are strictly tested and confirmed by our QC and QA, approved by Third Party Lab in China.So you will be assured with Good Quality if you choose us. We welcome you test the product and hope to get your feedback.

    3.Can I get a Free sample
    Yes, For most products we can provide you a free sample, You only need to pay for Shipping. Plesae be free to consult our salesman.
    For a larger quantity, we always support you with better price.

    4. What's your main payment method
    T/T (Bank transfer), MoneyGram, Wechat,Alipay,Credit card payment.

    5.How long does it take to the goods arrived
    It is Depending on your location:
    5-7 days by DHL,UPS,TNT, FEDEX, HKEMS,Netherlands post.
    7-20 days by DDP special line.
    5-8 days by Air
    20-35 days by Sea

    Basic Info
    Product Name:

    2-Propenoic acid, 3-[1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-1H-pyrrolo[2,3-b]pyridin-3-yl]-2-cyano-, (2E)-

    Other Name:

    2-Propenoic acid, 3-[1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-1H-pyrrolo[2,3-b]pyridin-3-yl]-2-cyano-, (2E)-;JXL-069;PP405,JXL-069;JXL-069,pp405;PP405

    CAS No.:

    2260696-63-5

    Molecular Formula:

    C20H11F6N3O2

    Molecular Weight:

    439.31

    Categories:

    Inhibitors

    Characteristics
    Density:

    1.44±0.1 g/cm3(Predicted)

    Boiling Point:

    521.3±50.0 °C(Predicted)

    PKA:

    0.65±0.19(Predicted)

    Research
    Class:

    Pan-FGFR tyrosine kinase inhibitor (FGFR1-4); antineoplastic (ATC L01EN01)

    Status:

    Approved (FDA accelerated approval 2019-04-12; converted to regular approval 2024-01-19; EMA approval 2024-08)

    Mechanism:

    Erdafitinib is an orally bioavailable, functionally selective small-molecule inhibitor of fibroblast growth factor receptors 1-4 (FGFR1-4). It inhibits FGFR tyrosine kinase activity (IC50 1.2-5.7 nM), blocking downstream RAS-MAPK/ERK and PI3K-AKT signaling that drives proliferation and survival of tumor cells harboring activating FGFR alterations (mutations, amplifications, or fusions). Rapid lysosomal uptake contributes to prolonged inhibition of FGFR signaling.

    EC50 (Fgfr1 Ic50):

    1.2 nM

    EC50 (Fgfr3 Ic50):

    3.0 nM

    EC50 (Fgfr2 Ic50):

    2.5 nM

    EC50 (Fgfr4 Ic50):

    5.7 nM

    EC50 (Vegfr2 Ic50):

    36.8 nM (approximately 30-fold selectivity vs FGFR1)

    Source:

    Perera TPS, et al. Mol Cancer Ther. 2017;16(6):1010-1020.DOI

    Clinical Development:

    NCT02365597; NCT03390504

    FDA:

    Balversa (approved 2019-04-12)

    References
    ChEMBL:

    CHEMBL3545376

    DrugBank:

    DB12147

    KEGG DRUG:

    D10927

    PubChem:

    PubChem

    Disclaimer:

    Erdafitinib (Balversa) is a prescription medicine approved by the US FDA and the EMA for specific oncology indications. ECHEMI lists this product for industrial sourcing and supply-chain reference only. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or a substitute for approved therapy. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

  • Seller Information
    Business Type:

    Distributor

    Main Products:

    CHEMICALS

    Location:

    No. 109, Chailu Street, Qingnian Park Subdistrict, Huaian District, Jinan City, Shandong Province 280

    Year of Establishment:

    2026

    Shandong Guozhao Import and Export Co., Ltd., located at No. 280, Chalu Street, Qingnian Park Subdistrict, Huaiyin District, Jinan City, Shandong Province, primarily engages in import and export of goods; sales of chemical products (excluding licensed chemical products); sales of specialty chemical products (excluding hazardous chemicals); sales of plastic products; sales of metal products; sales of building materials; sales of architectural decoration materials; sales of daily-use chemical products; sales of food additives; sales of feed additives; sales of fertilizers; sales of batteries; and general cargo warehousing services (excluding items requiring licensing or approval, such as hazardous chemicals).

  • Inquiry History
    39 Inquiries
    Country Product Purchase Quantity Date Posted
    Lithuania

    2260696-63-5

    1 KG Oct 13, 2025
    United States

    JXL-082 2260696-63-5

    5 G Nov 1, 2025
    United States

    JXL-082 2260696-63-5 for Anti Hair Loss JXL082

    5  Jan 26, 2026
    United States

    JXL-069 2260696-63-5 for Anti Hair Loss JXL 069

    1 G Aug 9, 2025
    United States

    PP405/JXL-069

    1 G Feb 19, 2026
    United Kingdom

    Jxl069

    1 MG Oct 17, 2026
    United Kingdom

    Jxl069 - pp405

    10 MT Oct 12, 2026
    United States

    JXL-069

    3 MT May 7, 2026
    Brazil

    PP405

    20  Mar 5, 2026
    Canada

    JXL-069

    10 MG Feb 24, 2026
    United States

    JXL-069

    100 G Feb 7, 2026
    Australia

    JXL-069

    1 G Jan 14, 2026
    Australia

    PP405

    10 G Dec 11, 2025
    United States

    JXL-069

    10 MT Nov 7, 2025
    United Kingdom

    JXL-069

    1 MT Sep 8, 2025
    Australia

    JXL069

    1 KG Aug 26, 2025
    Germany

    jxl-069

    1 G Aug 22, 2025
    United States

    Jxl-069

    1 G Aug 5, 2025
    United States

    Jxl-069

    100 G Aug 7, 2026
    United States

    PP405

    5 G Mar 26, 2026
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