Tacrolimus high pure 99% raw material powder CAS 104987-11-3
2 Inquiries
104987-11-3
Pharmaceutical Grade
99%
shenzhen
None
1kg/bag 25kg/drum
2026-10-17
API
-
Product Description
-
Seller Information
-
Inquiry History
-
DescriptionECHEMI Editorial ReferenceTacrolimus is a macrocyclic lactone with potent immunosuppressive properties. Tacrolimus binds to FK506 binding protein (FKBP) to form a complex and inhibits calcineurin phosphatase.Basic Info
-
Product Name:
Tacrolimus
Other Name:15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-,(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-;15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-,[3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-;15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-,(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-;(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone;FR 900506;FK 506;Tsukubaenolide;L 679934;Fujimycin;(-)-FK 506;Tacrolimus;Prograf;Protopic;Advagraf;TacroBell;FK506;Prograph;Envarsus XR;Astagraf XL;Hecoria;Tacropic;Protopy;Modigraf;Envarsus
CAS No.:104987-11-3
Molecular Formula:C44H69NO12
InChIKeys:InChIKey=QJJXYPPXXYFBGM-LFZNUXCKSA-N
Molecular Weight:804.02
Exact Mass:804.02
EC Number:1308068-626-2
DSSTox ID:DTXSID5046354
Categories:
Characteristics-
PSA:
178 Ų
XLogP3:3.3
Appearance:white solid
Density:1.2±0.1 g/cm3
Melting Point:113-115°C
Flash Point:2℃
Refractive Index:1.549
Water Solubility:Freely soluble in DMSO or ethanol. Poorly soluble in water.soluble in dimethyl sulfoxide, ethanol, water, acetone, chloroform, ethyl acetate, ether, methanol and dimethyl formamide.DMSO: >3 mg/mL
Storage Conditions:−20°C
Vapor Pressure:8.37X10-32 mm Hg at 25 °C (est)
Henrys Law Constant:Henry's Law constant = 4.74X10-24 atm-cum/mol at 25 °C (est)
Dissociation Constants:pKa1 = 2.94; pKa2 = 9.95; pKa3 = 14.07 (est)
Experimental Properties:Hydroxyl radical reaction rate constant = 3.81X10-10 cu cm/molec-sec at 25 °C (est)|Ozone radical reaction rate constant = 8.719X10-16 cu cm/molec-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
Reproductive toxicity, Category 2
Specific target organ toxicity â repeated exposure, Category 1
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H301 Toxic if swallowed
H361 Suspected of damaging fertility or the unborn child
H372 Causes damage to organs through prolonged or repeated exposure
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P318 IF exposed or concerned, get medical advice.
P319 Get medical help if you feel unwell.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
-
-
Seller Information
-
Business Type:
Trader
-
Main Products:
API
-
Location:
1806 Building B,Science Building,Hongkong Road,Wuhan City,Hubei Province
-
Year of Establishment:
2024
-
-
Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted 
Uzbekistan
China GMP Factory Direct Supply 99% Purity Tacrolimus FK-506 powder CAS 104987-11-3 Sinoway
1 KG Oct 12, 2023 
Saudi Arabia
Tacrolimus
10 G Sep 14, 2024 Post an enquiry for this product
More from this Seller
-
-
![Erdafitinib Raw Powder 99% Purity 1346242-81-6]( "Erdafitinib Raw Powder 99% Purity 1346242-81-6")
-
Erdafitinib Raw Powder 99% Purity 1346242-81-6
Pharmaceutical Grade / 99%
$1/G FOB
-
-
-
![Ru-58841 Powder high purity 99% CAS 154992-24-2 Ru 58841 / Ru58841]( "Ru-58841 Powder high purity 99% CAS 154992-24-2 Ru 58841 / Ru58841")
-
Ru-58841 Powder high purity 99% CAS 154992-24-2 Ru 58841 / Ru58841
Pharmaceutical Grade / 98%
-
-
-
![Ginsenoside CK CAS 39262-14-1 98%]( "Ginsenoside CK CAS 39262-14-1 98%")
-
Ginsenoside CK CAS 39262-14-1 98%
Food Grade / 98%
$1/KG EXW
-
-
-
![Nicotinamide Mononucleotide Reduced(NMNH) high pure 99% raw material powder CAS 108347-85-9]( "Nicotinamide Mononucleotide Reduced(NMNH) high pure 99% raw material powder CAS 108347-85-9")
-
Nicotinamide Mononucleotide Reduced(NMNH) high pure 99% raw material powder CAS 108347-85-9
Pharmaceutical Grade / 99%
$1/G FOB
-
-
-
![Estradiol Enanthate CAS 4956-37-0 Oestradiol 17-heptanoate raw powder purity 99%]( "Estradiol Enanthate CAS 4956-37-0 Oestradiol 17-heptanoate raw powder purity 99%")
-
Estradiol Enanthate CAS 4956-37-0 Oestradiol 17-heptanoate raw powder purity 99%
Pharmaceutical Grade / 98%
-
-
-
![PP405 powder JXL069 CAS 2260696-63-5 for Anti Hair Loss Purity 99%]( "PP405 powder JXL069 CAS 2260696-63-5 for Anti Hair Loss Purity 99%")
-
PP405 powder JXL069 CAS 2260696-63-5 for Anti Hair Loss Purity 99%
Pharmaceutical Grade / 99%
-
Hot Related Products
-
![Ethyl acetate CAS#141-78-6]( "Ethyl acetate CAS#141-78-6")
Ethyl acetate CAS#141-78-6 -
![Ethyl acetate Acetic ester Acetic ether Ethyl ester of acetic acid 141-78-6 99.7% Colourless Liquid]( "Ethyl acetate Acetic ester Acetic ether Ethyl ester of acetic acid 141-78-6 99.7% Colourless Liquid")
Ethyl acetate Acetic ester Acetic ether Ethyl ester of acetic acid 141-78-6 99.7% Colourless Liquid -
![Industrial Grade 99.9% High Purity Ethyl Acetate Organic Solvent]( "Industrial Grade 99.9% High Purity Ethyl Acetate Organic Solvent")
Industrial Grade 99.9% High Purity Ethyl Acetate Organic Solvent -
![Ethyl acetate-]( "Ethyl acetate-")
Ethyl acetate- -
![Ethyl Acetate 99.7%]( "Ethyl Acetate 99.7%")
Ethyl Acetate 99.7% -
![Ethyl Acetate , Min99.5% Colorless, clear liquid]( "Ethyl Acetate , Min99.5% Colorless, clear liquid")
Ethyl Acetate , Min99.5% Colorless, clear liquid -
![Ethyl Acetate(141-78-6) 99% liquid]( "Ethyl Acetate(141-78-6) 99% liquid")
Ethyl Acetate(141-78-6) 99% liquid -
![99.9% Purity Ethyl Acetate CAS No: 141-78-6]( "99.9% Purity Ethyl Acetate CAS No: 141-78-6")
99.9% Purity Ethyl Acetate CAS No: 141-78-6 -
![Ethyl acetate 99% Liquid Professional producer Greenbo]( "Ethyl acetate 99% Liquid Professional producer Greenbo")
Ethyl acetate 99% Liquid Professional producer Greenbo -
![Factory Manufacturer Pure Nature Food Grade Corn Starch Cas 9005-25-8]( "Factory Manufacturer Pure Nature Food Grade Corn Starch Cas 9005-25-8")
Factory Manufacturer Pure Nature Food Grade Corn Starch Cas 9005-25-8
