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Erdafitinib 99% CAS 1346242-81-6 China original factory best price Quality Assured

Name: Erdafitinib 99% CAS 1346242-81-6 China original factory best price Quality Assured
Brand: XAHNB
SKU: pr2609172575
Price: 115 USD
Availability: InStock

TDS 337 Inquiries

Unit Price:

$115/G FOB

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CAS No.:

1346242-81-6

Grade:

Pharma Grade

Content:

99%

Port:

Shanghai

Brand:

XAHNB

Packaging:

100g/bag; 1kg/bag

Price valid (until):

2026-10-17

Contact Supplier

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HNB Biotech

Company Type:

Manufactory

Location:

China

Payment Terms:

L/C,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

7 days

Qualification:

Main Products:

Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive

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Product Description
Seller Information
Inquiry History

Description

Shop Pure GHK-Cu Copper peptide Cosmetics grade China factory supply directory-Detailed Image 1

Erdafitinib 99% CAS 1346242-81-6 China original factory best price Quality Assured

Looking forward to having a long-term cooperation with us in China

Welcome to visit our factory ! ! !

Items	Specifications
Product name	Erdafitinib
COA	Available
More details	Please contact us
Payment	TT; WorldFirst

Get COA & Price, please contact us NOW.

vicky@xahnb.com

008617392948731

Strength Supply
Tyra-300 Dabogratinib	2800223-30-5
Erdafitinib	1346242-81-6
Venetoclax ABT-199	1257044-40-8
LOXO-435 LY3866288	2833703-74-3
Odanacatib (MK-0822)	603139-19-1
Dabrafenib	1195765-45-7
Sipagladenant/kw-6356	858979-50-7
Sunitinib Malate	341031-54-7
Vorinostat cs-1949	149647-78-9
LOXO-292 Selpercatinib	2152628-33-4
Pazopanib hydrochloride	635702-64-6
Tofacitinib Citrate	540737-29-9
Hinokitiol	499-44-5
AZD-0780 Laroprovstat	2455427-91-3
AMG785 Romosozumab	909395-70-6
AP-811	124833-45-0
Salcaprozate sodium / SNAC	203787-91-1
pe-22-28	1801959-12-5
Cibinetide ARA290	1208243-50-8
Slu-pp-332	303760-60-3
Slu-pp-915	2285432-92-8
SANA	42571-07-3
Enclomiphene citrate	7599-79-3
LY2456302	1174130-61-0
Vosoritide acetate	1480724-61-5
KissPeptin-10	374675-21-5
ACE-083	81080-10-6
tesofensine	195875-84-4
Flibanserin	167933-07-5
Monepantel	887148-69-8
Daridorexant
Plecanatide	467426-54-6
abaloparatide	247062-33-5
Efmitermant alfa	81080-10-6
AMG131 INT131	315224-26-1
Clascoterone CB-03-01/CB0301/CB 0301	19608-29-8
Ptd-dBm	1609454-11-6
Astressin-B
PDP/ Pyrrolidinyl Diaminopyrimidine Oxide	55921-65-8
SM04554	1360540-81-3
OC000459 /Timapiprant	851723-84-7
Setipiprant	866460-33-5
RU58841	154992-24-2
Fluridil	260980-89-0
WAY200070	440122-66-7
Fevipiprant Qaw039 NVP-QAW039	872365-14-5
WAY316606	915759-45-4
JXL082	2260696-63-5
Jxl-069 PP405	2260696-63-5
Tak-653 Osavampator	1358751-06-0
Piperlongumine piplartine	20069-09-4
Minoxidil	38304-91-5
Ky19382	2226664-93-1
Aminexil、DIAMINOPYRIMIDINE OXIDE/ 2, 4-Diamino Pyrimidine-3-Oxide	74638-76-9
GHK-Cu
Way262611	1123231-07-1
Chir99021	252917-06-9
S-equol	94105-90-5

SHIPMENT:

Deliver from warehouse within 1-2 after confirming order.

Delivery:(Totally cost about 7-10 days)

Deliver from warehouse within 1-4 after confirming order.

It cost 1-3 days shipping to port city, Shanghai or Guangzhou.

It cost 5-8 days from port city to USA by Fedex.(Not include Chinese holiday)

PACKAGE:

The internal packing is sealed plastic bag with aluminium foil bag outside. the external packing is EMS waterproof bag.
Before-Sale Service:

---Any inquiries will be replied within 12 hours.

---Golden Manufactory under ISO/GMP with large stock.

---Dedication to quality,We have strict quality control system.

---OEM/ODM Available.

---Sample is available for your evaluation & Formulation development.

---Low MOQ: No worry about the big MOQ.

---Fast Delivery: Narmolly grt it within 7-10 days after confirming the order.

---Convenient Payment: Trade Assurance on Alibaba(Visa or Credit card), or TT

After-Sale Service:
---International Authorized Third-Party Test For The Products You Demand.
---60 Days Guarantee of quality of goods.

Shop Erdafitinib 99% CAS 1346242-81-6 China original factory best price Quality Assured-Detailed Image 4

Shop Erdafitinib 99% CAS 1346242-81-6 China original factory best price Quality Assured-Detailed Image 5

Xi'an Harmonious Natural Bio-Technology Co., Ltd. was founded in 2010, and located in Xian

International Logistics Industrial Zone, Xi'an City, Shaanxi Province, China. Now it is the

leading researcher and one of the biggest manufacturer in high technology API area.

There are 8 experts in our research team. We insist in innovation and produce high quality

products. And GMP standard workshop and complete stainless extraction equipment.

We have 2 sales departments over 20 people and sell our products all over the world.

We also have strong professional research and development team, talented personnel and

completely equipped laboratory for the quality controlling. Various Detection Device is

equipped in HNB company, such as HPLC, GC, Spectrophotometer, AAS, Polarimeter, Auto

titrators, BOD Incubators, COD Incubators, Melting point apparatus and so on.

HNB mainly engaged in export of products including, without limitation, pharmaceutical raw

materials both for vet and human, also Vitamins, Amino Acids, minerals, peptides, plant

extract, feed and food additives.

Our company's business is based on Honest, Trustworthy, Constantly to Go Beyond and

Achieve Mutual Win. Sincerely hope to strengthen exchanges and cooperation with friends

from both home and abroad.

Passion to innovate, Power to deliver!

RFQ

Q1 Can i get some samples?

A1 Yes, we can supply the free sample, but the shipping cost be paid by our customers.

Q2 How to start orders or make payments?

A2 Proforma invoice will be sent first after confirmation of order, enclosed our bank information.

Payment by T/T,or Paypal or Escrow(Alibaba).

Q3 How to confirm the Product Quality before placing orders?

A3 You can get free samples for some products,you only need to pay the shipping cost or arrange a courier

to us and take the samples. You can send us your product specifications and requests,we will manufacture

the products according to your requests.

Q4 What’s your MOQ?

A4 Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge

is 100% paid.

Q5 How about delivery leadtime?

A5 Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)

Q6 Is there a discount?

A6 Different quantity has different discount.

Q7 How do you treat quality complaint?

A7 First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem

caused by us, we will send you free goods for replacement or refund your loss.

Q8 How to contact us ?

A8 You can choose your interested products and send inquiry to us.

ECHEMI Editorial Reference

Erdafitinib (JNJ-42756493) is a potent and orally available FGFR family inhibitor; inhibits FGFR1/2/3/4 with IC50s of 1.2, 2.5, 3.0 and 5.7 nM, respectively.
In early April of 2019, the US FDA approved Janssen Pharmaceutical Companies' brand name Balversa (erdafitinib) as the first-ever fibroblast growth factor receptor (FGFR) kinase inhibitor indicated for patients with locally advanced or metastatic urothelial carcinoma, with susceptible FGFR3 or FGFR2 genetic alterations, that has progressed during or following platinum-containing chemotherapy, including within 12 months of neoadjuvant or adjuvant platinum-containing chemotherapy. At the same time, the FDA also approved the therascreen FGFR RGQ RT-PCR Kit (Qiagen) for utilization as a companion diagnostic with erdafitinib for selecting patients for the indicated therapy. Erdafitinib's innovation lies in the fact that it is the first personalized treatment targeting susceptible FGFR genetic alterations for patients with metastatic bladder cancer, which demonstrates the design of erdafitinib in developing more personalized and precision medicines with the capacity to target cancer treatment to a patient's specific genetic mutation. Considering urothelial cancer is statistically the fourth most common kind of cancer in the world, the introduction of erdafitinib offers a welcome new option in the ever-expanding therapeutic tool kit to treat such prevalent medical conditions. Nevertheless, although erdafitinib was granted Breakthrough Therapy designation and Accelerated Approval from the FDA so as to allow the agency to focus on and expedite the approval process for a medication indicated for a serious condition that fills an unmet medical need using clinical trial data that is believed to predict a genuine clinical benefit for patients with the given condition, such designations mean further ongoing clinical trials are necessary to confirm the clinical benefit of erdafitinib going forward.|Erdafitinib is an oral small molecule inhibitor of fibroblast growth factor receptors (FGFR) 1 to 4 that is used in the therapy of locally advanced, unresectable or metastatic urothelial carcinoma. Erdafitinib has been associated with a high rate of serum enzyme elevations during therapy, but has not been linked to cases of clinically apparent acute liver injury.|Erdafitinib is an orally bioavailable, pan fibroblast growth factor receptor (FGFR) inhibitor with potential antineoplastic activity. Upon oral administration, erdafitinib binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways and thus the inhibition of tumor cell proliferation and tumor cell death in FGFR-overexpressing tumor cells. FGFR, upregulated in many tumor cell types, is a receptor tyrosine kinase essential to tumor cell proliferation, differentiation and survival.

Certificates

Basic Info

Product Name:

Erdafitinib

Other Name:

1,2-Ethanediamine,N1-(3,5-dimethoxyphenyl)-N2-(1-methylethyl)-N1-[3-(1-methyl-1H-pyrazol-4-yl)-6-quinoxalinyl]-;N1-(3,5-Dimethoxyphenyl)-N2-(1-methylethyl)-N1-[3-(1-methyl-1H-pyrazol-4-yl)-6-quinoxalinyl]-1,2-ethanediamine;Erdafitinib;JNJ 42756493;Balversa;1620332-47-9

CAS No.:

1346242-81-6

Molecular Formula:

C25H30N6O2

InChIKeys:

InChIKey=OLAHOMJCDNXHFI-UHFFFAOYSA-N

Molecular Weight:

446.54

Exact Mass:

446.54

UNII:

890E37NHMV

NCI Thesaurus Code:

C103273

ATC Code:

L - Antineoplastic and immunomodulating agents

Categories:

Drug Metabolism

Characteristics

PSA:

77.3

XLogP3:

3.2

Density:

1.2±0.1 g/cm3

Flash Point:

354.4±31.5 °C

Refractive Index:

1.618

Water Solubility:

<1 mg/mL

Research

Class:

Pan-FGFR tyrosine kinase inhibitor (FGFR1-4); antineoplastic (ATC L01EN01)

Status:

Approved (FDA accelerated approval 2019-04-12; converted to regular approval 2024-01-19; EMA approval 2024-08)

Mechanism:

Erdafitinib is an orally bioavailable, functionally selective small-molecule inhibitor of fibroblast growth factor receptors 1-4 (FGFR1-4). It inhibits FGFR tyrosine kinase activity (IC50 1.2-5.7 nM), blocking downstream RAS-MAPK/ERK and PI3K-AKT signaling that drives proliferation and survival of tumor cells harboring activating FGFR alterations (mutations, amplifications, or fusions). Rapid lysosomal uptake contributes to prolonged inhibition of FGFR signaling.

EC50 (Fgfr1 Ic50):

1.2 nM

EC50 (Fgfr3 Ic50):

3.0 nM

EC50 (Fgfr2 Ic50):

2.5 nM

EC50 (Fgfr4 Ic50):

5.7 nM

EC50 (Vegfr2 Ic50):

36.8 nM (approximately 30-fold selectivity vs FGFR1)

Source:

Perera TPS, et al. Mol Cancer Ther. 2017;16(6):1010-1020.DOI

Clinical Development:

NCT02365597; NCT03390504

FDA:

Balversa (approved 2019-04-12)

References

ChEMBL:

DrugBank:

KEGG DRUG:

PubChem:

Literature:

FDA: Approval announcement 2024-01-19; FDA: BALVERSA label (NDA 212018, BLC2001); NEJM: Loriot et al. (2023) — THOR Cohort 1; NEJM: Loriot et al. (2019) — BLC2001; Mol Cancer Ther: Perera et al. (2017) — discovery pharmacology

Disclaimer:

Erdafitinib (Balversa) is a prescription medicine approved by the US FDA and the EMA for specific oncology indications. ECHEMI lists this product for industrial sourcing and supply-chain reference only. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or a substitute for approved therapy. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

See More Erdafitinib Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Skin sensitization, Sub-category 1B

Serious eye damage, Category 1

Reproductive toxicity, Category 2

Specific target organ toxicity â repeated exposure, Category 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H302 Harmful if swallowed H317 May cause an allergic skin reaction H318 Causes serious eye damage H361 Suspected of damaging fertility or the unborn child H372 Causes damage to organs through prolonged or repeated exposure
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P203 Obtain, read and follow all safety instructions before use. P260 Do not breathe dust/fume/gas/mist/vapours/spray.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P333+P317 If skin irritation or rash occurs: Get medical help. P321 Specific treatment (see ... on this label). P362+P364 Take off contaminated clothing and wash it before reuse. P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P317 Get medical help. P318 IF exposed or concerned, get medical advice. P319 Get medical help if you feel unwell.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Erdafitinib Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive

Location:
6 floor Baoyilongji Building B Weiyang Area, Fengcheng 8 Road, Xi'an city, Shaanxi, 710000, China

Payment Terms:
L/C,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
7 days

Total Annual Revenue:
$5 million-$10 million

Total Employees:
51-100

Year of Establishment:
2017

Company Certificates
- ISO
- ISO
Xi'an Harmonious Natural Bio-Technology Co., Ltd. was founded in 2010, and located in Xian

International Logistics Industrial Zone, Xi'an City, Shaanxi Province, China. Now it is the

leading researcher and one of the biggest manufacturer in high technology API area.

There are 8 experts in our research team. We insist in innovation and produce high quality

products. And GMP standard workshop and complete stainless extraction equipment.

We have 2 sales departments over 20 people and sell our products all over the world.

We also have strong professional research and development team, talented personnel and

completely equipped laboratory for the quality controlling. Various Detection Device is

equipped in HNB company, such as HPLC, GC, Spectrophotometer, AAS, Polarimeter, Auto

titrators, BOD Incubators, COD Incubators, Melting point apparatus and so on.

HNB mainly engaged in export of products including, without limitation, pharmaceutical raw

materials both for vet and human, also Vitamins, Amino Acids, minerals, peptides, plant

extract, feed and food additives.

Our company's business is based on Honest, Trustworthy, Constantly to Go Beyond and

Achieve Mutual Win. Sincerely hope to strengthen exchanges and cooperation with friends

from both home and abroad.

Passion to innovate, Power to deliver !

Inquiry History

337 Inquiries

Country	Product	Purchase Quantity	Date Posted
Germany	High Quality Erdafitinib 99% powder 1346242-81-6 Erdafitinib	1 G	Aug 25, 2026
Vietnam	High Quality Erdafitinib 99% powder 1346242-81-6 Erdafitinib	1 G	Aug 18, 2026
United States	High Quality Erdafitinib 99% powder 1346242-81-6 Erdafitinib	1 G	Jul 26, 2026
Australia	High Quality Erdafitinib 99% powder 1346242-81-6 Erdafitinib	1 G	Aug 14, 2026
Poland	High Quality Erdafitinib 99% powder 1346242-81-6 Erdafitinib	1 G	Jul 28, 2026
Canada	Factory Direct Supply Erdafitinib Raw Powder 98% Purity Erdafitinib Powder 1346242-81-6	1 G	Sep 15, 2026
United Kingdom	Factory Direct Supply Erdafitinib Raw Powder 98% Purity Erdafitinib Powder 1346242-81-6	1 MT	Sep 4, 2026
Canada	Best Price Pure 98% HPLC JNJ-42756493 Erdafitinib Powder CAS 1346242-81-6	500 MG	Sep 1, 2026
Canada	Best Price Pure 98% HPLC JNJ-42756493 Erdafitinib Powder CAS 1346242-81-6	500 MG	Aug 25, 2026
United States	Factory Supply Erdafitinib CAS 1346242-81-6 99% High Purity FGFR Inhibitor API Powder	1 G	Sep 3, 2026
United States	Hot Selling ERDAFITINIB 1346242-81-6 Factory Supply Raw Materials High Qulity Wholesale price	3 MT	Jul 5, 2026
Australia	Erdafitinib	500 MG	Sep 16, 2026
Australia	Erdafitinib	1 G	Jul 18, 2026
Germany	Erdafitinib	500 MG	Jul 28, 2026
Cyprus	Erdafitinib	1 G	Jul 22, 2026
Bulgaria	Erdafitinib	500 MG	Jun 18, 2026
Spain	Erdafitinib	1	Sep 14, 2026
Germany	Erdafitinib	5 G	Sep 17, 2026
Netherlands	Erdafitinib	1 G	Sep 17, 2026
Switzerland	1g Erdafitinib raw powder >99% purity	1 G	May 22, 2026

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Erdafitinib 99% CAS 1346242-81-6 China original factory best price Quality Assured

Product Description

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