Pharmaceutical Grade 99% Selumetinib Raw Powder CAS 606143-52-6 Peritoneal Cancer Related Reagent

Product Description

Selumetinib is an orally active, small molecule with potential antineoplastic activity. Selumetinib is an ATP-independent inhibitor of mitogen-activated protein kinase kinase (MEK or MAPK/ERK kinase) 1 and 2. MEK 1 and 2 are dual specificity kinases that are essential mediators in the activation of the RAS/RAF/MEK/ERK pathway, are often upregulated in various cancer cells, and are drivers of diverse cellular responses, including proliferation. Inhibition of both MEK1 and 2 by selumetinib prevents the activation of MEK1/2 dependent effector proteins and transcription factors, thereby leading to an inhibition of cellular proliferation in various cancers.

Selumetinib is under investigation for the treatment of Carcinoma, Thymic, Non-Small Cell Lung Cancer, and Carcinoma, Small Cell Lung. AZD6244 has been investigated for the treatment and basic science of Melanoma, Solid Tumours, Breast Cancer, Non Small Cell Lung Cancer, and Non Small Cell Lung Carcinoma, among others.

Applications

It is widely used in life‑science laboratory research. Main application includes in‑vitro cell culture experiments, MAPK/ERK cell signal transduction pathway research, protein kinase target validation, compound drug screening, biochemical pharmacology study, mechanism exploration of cell proliferation and apoptosis, used as tool compound for inhibitor related academic research.

Packaging & Shipping

Company Profile

We are committed to providing customers with cost-effective plastic raw materials. Our factory has good working environment, complete supporting facilities and sufficient production capacity. We own advanced production technology and professional technical team. Our sales volume has maintained steady growth since establishment. We adhere to the business philosophy of "quality guaranteed, competitive price, customer first". We strive to provide sufficient supply and stable reliable product quality for customers. Business Philosophy: Integrity-oriented, win-win cooperation Enterprise Spirit: Trust, gratitude, equality and mutual respect Enterprise Mission: Create opportunities for employees, create value for customers, and assume social responsibility Corporate Values: Exceed customer expectations, foster team spirit, enhance employee value, and undertake social responsibility. We sincerely welcome global new & existing clients to cooperate with us! Our experienced team offers 24/7 support to ensure smooth communication and prompt problem-solving. Let's grow and thrive together in international

FAQ

1.Are you a factory or trading company
We are a company integrating manufacturer and trading company

2.How is the quality I want to test.
Before production and extraction, we will test all raw materials.Quality is our top priority. All products are strictly tested and confirmed by our QC and QA, approved by Third Party Lab in China.So you will be assured with Good Quality if you choose us. We welcome you test the product and hope to get your feedback.

3.Can I get a Free sample
Yes, For most products we can provide you a free sample, You only need to pay for Shipping. Plesae be free to consult our salesman.
For a larger quantity, we always support you with better price.

4. What's your main payment method
T/T (Bank transfer), MoneyGram, Wechat,Alipay,Credit card payment.

5.How long does it take to the goods arrived
It is Depending on your location:
5-7 days by DHL,UPS,TNT, FEDEX, HKEMS,Netherlands post.
7-20 days by DDP special line.
5-8 days by Air
20-35 days by Sea