SLU-PP-915/oxidative metabolism, heart failure & metabolic disease research/body shape

Description

This product is an organic compound with the identification number SLU-PP-915 and CAS number 2285432-92-8. It belongs to phenylthiophene amide compounds containing boronic acid groups. The molecular formula of the product is C₁₇H₁₃BFNO₃S, with a molecular weight of approximately 341.16. It normally appears as a white to off-white powder, and its purity can exceed 98% (determined by HPLC). As an intermediate and active small-molecule compound for biomedical research and development, this product can simultaneously target a class of receptors closely related to energy metabolism in human cells (referred to as ERR). It has been a research subject attracting considerable attention in the fields of energy metabolism and cardiovascular research in recent years. It is mainly supplied to pharmaceutical R&D institutions, research institutes and biotechnology companies. The product is recommended to be stored in a low-temperature, light-shielded and sealed environment.

Key Effects

Mitochondria in human cells are known as the "powerhouses" of the cell, responsible for converting nutrients from food into energy required for cellular activities. The core function of SLU-PP-915 is that it can simultaneously activate a class of ERR receptors related to energy metabolism within cells, enabling mitochondria to function better and helping cells, especially cardiac and skeletal muscle cells, utilize energy sources such as fatty acids more efficiently. Relevant studies show that this compound helps maintain the oxidative metabolic capacity of cells, boosts the energy supply of the heart, and may promote the transformation of skeletal muscle fibers into a more fatigue-resistant type. Its mechanism of action resembles some physiological changes induced by exercise training, so it is often used as a tool molecule in metabolic and exercise physiology research.

Its specific functions can be summarized as follows:
Activating energy metabolism receptors: Acts on three subtypes of ERR receptors at the same time to fully trigger energy metabolism regulatory signals;
Enhancing mitochondrial function: Improves the efficiency of mitochondria in energy processing and strengthens cellular utilization of energy substances such as fatty acids;
Supporting cardiac energy supply: Helps sustain the energy metabolic state of cardiomyocytes and provides references for research on conditions such as heart failure;
Regulating skeletal muscle fiber types: Can be explored for promoting the shift of skeletal muscle toward more fatigue-resistant oxidative fibers;
Serving as a metabolic regulation tool: Acts as an experimental tool compound for investigating mechanisms associated with energy expenditure, fat metabolism and exercise endurance.

Applications

This product is mainly applied in the field of biomedical research, especially in research directions related to energy metabolism, cardiovascular protection and exercise physiology. With its regulatory effect on energy metabolic pathways, this compound is used by research teams at home and abroad as an experimental tool and a research subject for candidate drugs. Its research scope covers multiple areas including metabolic diseases and cardiac function.

The main application fields can be summarized as follows:
Metabolic disease research: Used to explore the mechanisms of disorders related to energy metabolism such as obesity and diabetes;
Cardiovascular disease research: Used for research on energy metabolism mechanisms and therapeutic strategies of heart diseases like heart failure;
Mitochondria and energy metabolism research: Applied in basic scientific research on mitochondrial function, fatty acid metabolism and so on;
Muscle function and exercise physiology research: Used to investigate the mechanisms regulating muscle endurance, exercise capacity and fiber types;
Drug research and development as well as pharmacodynamic evaluation: Serves as a lead compound or tool molecule for the screening and evaluation of relevant candidate drugs;
Supply of scientific research reagents: Provided to laboratories of universities, research institutes and pharmaceutical enterprises as experimental materials for life science research.