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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > PVM/MA for Sale > Vorasidenib high pure 99% raw material powder CAS 1644545-52-7
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Vorasidenib high pure 99% raw material powder CAS 1644545-52-7

4 Inquiries

Unit Price:

$1/G FOB

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CAS No.:

1644545-52-7

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shenzhen

Brand:

None

Packaging:

1kg/bag 25kg/drum

Price valid (until):

2026-10-22

Company Type:
Trader
Location:
China
Qualification:
Main Products:

API

  • Product Description

  • Seller Information

  • Inquiry History

  • Description
    Shop High Qulity Voriconazole raw powder CAS 137234-62-9-Detailed Image 1


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    Items Specifications
    Product name: Vorasidenib
    CAS Number 1644545-52-7
    Purity ≥99%
    Appearance white powder
    Grade High purity Medical Grade
    Package  1kg/bag or 25kg/drum,according your inquiry
    Storage Preserve in tight containers,in a cool and dry place



    We are a dedicated supplier of APIs, nutritional supplement ingredients, and peptide raw materials, committed to making your procurement process simple, safe, and cost-effective.We cooperate with multiple pharmaceutical companies, we secure competitive pricing and low MOQs, accommodating both bulk commercial orders and small trial batches with equal flexibility.


    Feel free to contact us for any product inquiries via WhatsApp: +852 64634275 or email: sales01@meisangtrading.com



    Transportation method:

    Dedicated line, Express delivery, Air freight, sea freight

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    Shop Spermidine trihydrochloride powder CAS 334-50-9-Detailed Image 2 Shop Spermidine trihydrochloride powder CAS 334-50-9-Detailed Image 3



    ECHEMI Editorial Reference
    Vorasidenib is an orally available inhibitor of mutated forms of both isocitrate dehydrogenase type 1 (IDH1, IDH1 [NADP+] soluble) in the cytoplasm and type 2 (IDH2, isocitrate dehydrogenase [NADP+], mitochondrial) in the mitochondria, with potential antineoplastic activity. Upon administration, vorasidenib specifically inhibits mutant forms of IDH1 and IDH2, thereby inhibiting the formation of the oncometabolite 2-hydroxyglutarate (2HG) from alpha-ketoglutarate (a-KG). This prevents 2HG-mediated signaling and leads to both an induction of cellular differentiation and an inhibition of cellular proliferation in tumor cells expressing IDH mutations. In addition, vorasidenib is able to penetrate the blood-brain barrier (BBB). IDH1 and 2, metabolic enzymes that catalyze the conversion of isocitrate into a-KG, play key roles in energy production and are mutated in a variety of cancer cell types. In addition, mutant forms of IDH1 and 2 catalyze the formation of 2HG and drive cancer growth by blocking cellular differentiation and inducing cellular proliferation.

    Basic Info
    Product Name:

    PVM/MA

    Other Name:

    PF06291874;E-7386;FM381 FM-381;6-(6-chloropyridin-2-yl)-N2,N4-bis((R)-1,1,1-trifluoropropan-2-yl)-1,3,5-triazine-2,4-diamine;PVM/MA;S-N-NITROSO-2-METHYLPIPERIDINE;PCB138/160;FLEABUSTERSRXPOWDER

    CAS No.:

    1644545-52-7

    Molecular Formula:

    C14H13ClF6N6

    InChIKeys:

    QCZAWDGAVJMPTA-RNFRBKRXSA-N

    Molecular Weight:

    414.74

    Exact Mass:

    414.0794411

    UNII:

    789Q85GA8P

    NCI Thesaurus Code:

    C152914

    Color/Form:

    Light yellow to light brown

    Characteristics
    Density:

    1.491±0.06 g/cm3(Predicted)

    Boiling Point:

    467.5±55.0 °C(Predicted)

    PKA:

    1.49±0.41(Predicted)

    Critical Temperature & Pressure:

    Store at -20°C

  • Seller Information
    Business Type:

    Trader

    Main Products:

    API

    Location:

    1806 Building B,Science Building,Hongkong Road,Wuhan City,Hubei Province

    Year of Establishment:

    2024

  • Inquiry History
    4 Inquiries
    Country Product Purchase Quantity Date Posted
    Pakistan

    Vorasidenib

    1 G May 17, 2026
    Pakistan

    Vorasidenib

    100 MG May 19, 2026
    Pakistan

    Vorasidenib

    100 G May 18, 2026
    Pakistan

    Vorasidenib

    1 KG May 27, 2025
    Post an enquiry for this product
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