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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Relugolix for Sale > Relugolix CAS 737789-87-6 Potent Oral GnRH Receptor Antagonist for Prostate Cancer and Uterine Fibroid Research fkhc
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Relugolix CAS 737789-87-6 Potent Oral GnRH Receptor Antagonist for Prostate Cancer and Uterine Fibroid Research fkhc

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Unit Price:

$100-130/G FOB

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CAS No.:

737789-87-6

Grade:

Reagent Grade

Content:

99%

Port:

qingdao

Brand:

//

Packaging:

10mg, 25mg, 50mg, 100mg, 1g

Sample Available:

Yes

Price valid (until):

2026-10-25

Company Type:
Trader
Location:
China
Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
7 days
Qualification:
Main Products:

Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    —— Product Specification ——

    Parameter Specification Details
    Product Name Relugolix TAK-385; RVT-601
    CAS Number 737789-87-6 737789-87-6
    Molecular Formula C₂₉H₂₇F₂N₇O₅S 29 carbons, 27 hydrogens, 2 fluorine, 7 nitrogens, 5 oxygens, 1 sulfur
    Molecular Weight 623.63 g/mol —
    Appearance Crystalline solid Visual inspection
    Purity ≥98.0% Determined by HPLC
    IC₅₀ (Human GnRH receptor) 0.85 nM Potent GnRH receptor antagonism
    IC₅₀ (Monkey GnRH receptor) 0.32 nM High binding affinity
    IC₅₀ (Rat GnRH receptor) 9,800 nM 30,000-fold decrease vs. human
    Melting Point 228°C (decomp.) —
    Density 1.442 ± 0.06 g/cm³ (Predicted) —
    pKa 13.17 ± 0.70 (Predicted) —
    Solubility DMSO: 20.0 mg/mL (32.1 mM, max); Ethanol: 1.0 mg/mL (1.6 mM, max) —
    Storage -20°C Protect from light and moisture
    Packaging 5mg, 10mg, 25mg, 50mg, 100mg, 500mg Amber glass vials
    Application Research use only Prostate cancer research, uterine fibroid research, endometriosis research


    —— Product Detail ——

    Product Overview

    Relugolix (CAS 737789-87-6), also known as TAK-385 or RVT-601, is a potent, orally active, non-peptide antagonist of the human gonadotropin-releasing hormone (GnRH) receptor developed by Takeda Pharmaceutical and Myovant Sciences. It appears as a crystalline solid with the molecular formula C₂₉H₂₇F₂N₇O₅S and a molecular weight of 623.63 g/mol.



    Packaging & Shipping

      • Research quantities: 10mg, 25mg, 50mg amber glass vials

      • Bulk quantities: 100mg, 1g, 5g amber glass bottles

      • Custom packaging available upon request

      • Not classified as hazardous material for transport under normal conditions

      • Product for research and analytical use only; not for human or veterinary use

    Shop CAS 18048-64-1 Eltrombopag Intermediate for Pharmaceutical Research  kr-Detailed Image 1

    — Company profile ——


     Shop CAS 1231930-42-9 Abemaciclib Intermediate for Pharma researech use KR-Detailed Image 1

    Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

    Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

    We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

    To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.

    Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.

     

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    —— Q&A ——

    Q1: How to confirm the product quality before placing orders?
    A: By sending you available samples. Or if you have special requirements for the goods, we can prepare samples according to your requirements for confirmation.

    Q2: Can you supply free samples?
    A: Yes, we can provide a free sample, but the shipping cost will be paid by the customers. You can either pay the shipping cost or arrange a courier to collect the samples.

    Q3: How do you treat quality complaints?
    A: All our products are strictly tested by our QC and confirmed by QA; unqualified material will not be released to customers. If any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.

    Q4: What is your MOQ? Is there a discount?
    A: For highvalue products, our MOQ starts from 1g and generally starts from 10g. For other lowprice products, our MOQ starts from 100g and 1kg.
    Q: Is there a discount?
    A: Yes, for larger quantities, we always support with better prices.

    Q5: How to start orders or make payments?
    A: You can send us your Purchase Order (if your company has one), or just send a simple confirmation by email or via Trade Manager. We will then send you a Proforma Invoice with our bank details for your confirmation, and you can make payment accordingly. If you have other preferred payment methods, we are open to discussion and negotiation.



    ECHEMI Editorial Reference
    Relugolix is a gonadotropin-releasing hormone (GnRH) receptor antagonist used in the treatment of several hormone-responsive conditions. It was first approved in Japan in 2019, under the brand name Relumina, for the symptomatic treatment of uterine fibroids, and more recently by the United States' FDA in 2020, under the brand name Orgovyx, for the treatment of advanced prostate cancer. Relugolix has also been studied in the symptomatic treatment of endometriosis. Relugolix is the first (and currently only) orally-administered GnRH receptor antagonist approved for the treatment of prostate cancer - similar therapies such as [degarelix] require subcutaneous administration - and therefore provides a less burdensome therapeutic option for patients who might otherwise require clinic visits for administration by healthcare professionals. In addition to its relative ease-of-use, relugolix was shown to be superior in the depression of testosterone levels when compared to [leuprolide], another androgen deprivation therapy used in the treatment of prostate cancer.|Relugolix is a Gonadotropin Releasing Hormone Receptor Antagonist. The mechanism of action of relugolix is as a Gonadotropin Releasing Hormone Receptor Antagonist, and Cytochrome P450 3A Inducer, and Cytochrome P450 2B6 Inducer, and Breast Cancer Resistance Protein Inhibitor, and P-Glycoprotein Inhibitor. The physiologic effect of relugolix is by means of Decreased GnRH Secretion.|Relugolix is an orally available, non-peptide gonadotropin-releasing hormone (GnRH or luteinizing hormone-releasing hormone (LHRH)) antagonist, with potential antineoplastic activity. Relugolix competitively binds to and blocks the GnRH receptor in the anterior pituitary gland, which both prevents GnRH binding to the GnRH receptor and inhibits the secretion and release of both luteinizing hormone (LH) and follicle stimulating hormone (FSH). In males, the inhibition of LH secretion prevents the release of testosterone from Leydig cells in the testes. Since testosterone is required to sustain prostate growth, reducing testosterone levels may inhibit hormone-dependent prostate cancer cell proliferation.
    Relugolix (TAK-385) is a potent, orally active, nonpeptidic gonadotropin-releasing hormone (GnRH) antagonist. It possesses high affinity and potent antagonistic activity for human receptor (binding IC50=0.33 nM) and monkey receptor (IC50=0.32 nM) compared with TAK-013 (HY-100209). Relugolix is used for the study of sex-hormone-dependent diseases, such as including endometriosis, uterine fibroids and prostate cancer et al.

    Certificates
    • Relugolix CAS 737789-87-6 Potent Oral GnRH Receptor Antagonist for Prostate Cancer and Uterine Fibroid Research fkhc Certificates 1 TDS

    Basic Info
    Product Name:

    Relugolix

    Other Name:

    Relugolix;Altropane;TKA-385 Relugolix;1-[4-[1-[(2,6-difluorophenyl)methyl]-5-(dimethylaminomethyl)-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-6-thieno[4,5-e]pyrimidinyl]phenyl]-3-methoxyurea;Relugolix TAK-385;TAK-385,Relugolix;CS-2851;TAK-385;TAK 385;TAK385

    CAS No.:

    737789-87-6

    Molecular Formula:

    C29H27F2N7O5S

    InChIKeys:

    AOMXMOCNKJTRQP-UHFFFAOYSA-N

    Molecular Weight:

    623.63

    Exact Mass:

    623.63

    EC Number:

    237-099-7

    UNII:

    P76B05O5V6

    DSSTox ID:

    DTXSID40224167

    NCI Thesaurus Code:

    C114498

    Color/Form:

    White to off-white

    ATC Code:

    H01CC54

    Characteristics
    Density:

    1.442±0.06 g/cm3(Predicted)

    Melting Point:

    228 °C (decomp)(Solv: ethyl acetate (141-78-6); tetrahydrofuran (109-99-9))

    PKA:

    13.17±0.70(Predicted)

    Critical Temperature & Pressure:

    Store at -20°C

    Hazard Identification

    Classification of the substance or mixture

    no data available

    GHS label elements, including precautionary statements

    Pictogram(s) no data available
    Signal word

    no data available

    Hazard statement(s)

    no data available

    Precautionary statement(s)
    Prevention

    no data available

    Response

    no data available

    Storage

    no data available

    Disposal

    no data available

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

    Location:

    RONGSHENG BEIYUANDAJIE 9, LICHENG DISTRICT,JINAN, SHANDONG CHINA

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7 days

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2022

    Jinan Topfull Chemical Co., Ltd. is a global chemical Industrial and focuses on advanced chemical technology. Specialized in Cosmetic materials, water treatment, fine chemicals and so on. We are looking forward to working together with the people of all circles at home and abroad to seek common development!
  • Inquiry History
    6 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    99% Pharmacy Grade Relugolix

    100 G Nov 30, 2025
    Greece

    Relugolix tablets

    120 MG Nov 14, 2025
    Bangladesh

    RELUGOLIX

    1 20' Fcl Dec 12, 2025
    Greece

    Relugolix tablets

    120 MG Nov 14, 2025
    United States

    Relugolix

    10 G Sep 15, 2025
    United Kingdom

    Ascorbic Acid

    1.00 KG Sep 10, 2026
    Post an enquiry for this product
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