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Melanotan II(20MG)

Name: Melanotan II(20MG)
Brand: Pharma;Conutrix
SKU: pr2610071099
Price: 10 USD
Availability: InStock

19 Inquiries

Unit Price:

$10/UNIT FOB

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CAS No.:

75921-69-6

Grade:

Pharmaceutical Grade

Content:

99%

Port:

tianjin

Brand:

Pharma;Conutrix

Packaging:

10 vials/box

Price valid (until):

2026-11-20

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Anhui Ruibang Trading Co., Ltd

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Retatrutide,Tirzepatide,Semaglutide,Cynomorium Songaricum Extract,Bull Penis Powder,Deer Penis Extract

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Product Description
Seller Information
Inquiry History

Description

Product Detail

. Product Overview

Alprostadil, also known as Prostaglandin E1 (PGE1), is a high-purity synthetic bioactive prostaglandin molecule with pharmaceutical-grade specifications. Though not a traditional amino-acid peptide, it exhibits peptide-like high biological activity and precise signaling regulation, widely classified as a specialty therapeutic biomolecule. Produced via standardized synthetic processes with ≥99% HPLC purity, this stable small-molecule compound features ultra-high biological availability, consistent batch repeatability and low systemic irritation. As a potent EP receptor agonist, Alprostadil specializes in vascular dilation, microcirculation activation, smooth muscle relaxation and anti-platelet aggregation. It is extensively applied in vascular function research, peripheral circulation repair, microvascular lesion conditioning and high-end pharmaceutical raw material formulation development.

2. Basic Specifications

Product Name: Alprostadil Pharmaceutical Grade
Full Name: Prostaglandin E1 (PGE1)
CAS Number: 745-65-3
Molecular Weight: 354.48 Da
Purity: ≥99.0% (HPLC)
Appearance: White sterile lyophilized powder
Solubility: Soluble in sterile water and aqueous solvent
Core Feature: Potent microcirculation activator & vascular smooth muscle regulator
Grade Standard: Pharmaceutical raw material grade, low endotoxin, heavy metal compliant
Storage: -20°C sealed, dry and protected from light
Shelf Life: 24 months under standard storage conditions

3. Mechanism of Action

Alprostadil exerts targeted vascular and tissue regulation by selectively binding to EP prostanoid receptors distributed on vascular smooth muscle, endothelial cells and peripheral tissues. It activates intracellular adenylate cyclase, elevates cAMP levels and reduces intracellular calcium concentration, triggering continuous vascular smooth muscle relaxation and systemic microvascular dilation. Meanwhile, it effectively inhibits platelet adhesion and aggregation, improves blood rheology, and eliminates microcirculation stasis and hypoxic damage.

Different from common vasodilators with transient efficacy, Alprostadil delivers dual vascular protection and metabolic optimization. It repairs damaged vascular endothelial function, improves peripheral tissue oxygen and nutrient supply, blocks inflammatory cascades caused by microcirculation disorders, and achieves long-term stabilization of vascular physiological function without endocrine disturbance or drug resistance.

4. Core Benefits & Applications

Microcirculation Activation: Dilates peripheral microvessels, improves blood flow velocity, relieves tissue ischemia and hypoxia, and repairs microcirculation dysfunction caused by aging and vascular sub-health.
Vascular Endothelial Repair: Protects vascular endothelial cells, reduces endothelial inflammatory damage, improves vascular elasticity, and delays peripheral vascular tissue degeneration.
Anti-Thrombotic & Blood Regulation: Inhibits abnormal platelet aggregation, optimizes blood rheological properties, and reduces the risk of microvascular stasis and occlusion.
Smooth Muscle Regulation: Relaxes cavernosal and peripheral smooth muscle, improves local blood perfusion, and supports physiological tissue function recovery.
Professional Research Use: High-purity API for vascular pharmacology, microcirculation mechanism research, endothelial repair study and pharmaceutical formulation development.

5. Advantages of 99% Pharmaceutical-Grade Alprostadil

Precise EP receptor targeting: Specific binding to prostanoid receptors, accurate vascular regulation with minimal systemic side effects
Dual dilation & repair efficacy: Combines rapid microcirculation activation and long-term endothelial repair, superior to single-effect vasodilators
Small-molecule high permeability: Ultra-low molecular weight ensures fast tissue penetration and high bioavailability
≥99% HPLC ultra-high purity, strict single impurity control, zero batch difference for synthetic prostaglandin biomolecule
Low endotoxin and ultra-low heavy metals, fully compliant with pharmaceutical raw material standards, stable activity and formulation compatibility

6. Safety & Usage Features

Alprostadil is a high-safety pharmaceutical biomolecule with reliable biological tolerance. It features mild physiological vascular regulation, no hormone interference, no cumulative toxicity and no drug dependence. Standard cyclic use safely optimizes microcirculation, repairs endothelial damage and improves tissue hypoxia status, suitable for long-term vascular sub-health conditioning and high-standard biomedical research applications.

Items	Specifications

ECHEMI Editorial Reference

ChEBI: Afamelanotide is a polypeptide comprising of 13 amino acids which is an analogue of alpha-melanocyte stimulating hormone. It is approved as a dermatologic drug for the prevention of phototoxicity in adult patients with erythropoietic protoporphyria. It has a role as a dermatologic drug.
Melanotan-1 stimulating hormone is a potent analogue of α;-melanocyte-stimulating hormone (α -MSH). αMSH is a tridecapeptide, mostly produced by the cells in the brain, pituitary and in circulation.

Basic Info

Product Name:

Melanotan-1

Other Name:

[NLE4,D-PHE]ALPHA-MELANOCYTE STIMULATING HORMONE;(NLE4,D-PHE7)-ALPHA-MSH;[Nle4,D-Phe7]α-MSH;Ac-L-Ser-L-Tyr-L-Ser-L-Nle-L-Glu-L-His-D-Phe-L-Arg-L-Trp-Gly-L-Lys-L-Pro-L-Val-NH2;N-Ac-L-Ser-L-Tyr-L-Ser-L-Nle-L-Glu-L-His-D-Phe-L-Arg-L-Trp-Gly-L-Lys-L-Pro-L-Val-NH2;[Nle4,DPhe7] a-MSH, amide;[Nle4,DPhe7] a-MSH, amide:Melanotan Ⅰ;[Nle4, D-Phe7]-α-MSH, amide

CAS No.:

75921-69-6

Molecular Formula:

C78H111N21O19

InChIKeys:

UAHFGYDRQSXQEB-LEBBXHLNSA-N

Molecular Weight:

1646.85

EC Number:

211-519-9

Color/Form:

White to off-white

Categories:

Bulk Drug Intermediates

Characteristics

Density:

1.46±0.1 g/cm3(Predicted)

Water Solubility:

Soluble to 0.60 mg/ml in sterile water

PKA:

4.43±0.10(Predicted)

Critical Temperature & Pressure:

−20°C

Research

Class:

Synthetic cyclic heptapeptide / non-selective melanocortin receptor agonist

Status:

Research compound — NOT FDA approved. FDA issued warning letters. WADA banned substance.

Mechanism:

A synthetic cyclic heptapeptide (Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂) analog of α-MSH. Melanotan II is a high-affinity non-selective agonist at MC1R, MC3R, MC4R, and MC5R. MC1R activation induces melanogenesis (skin darkening/tanning); MC4R activation affects sexual function, appetite suppression, and energy homeostasis. Carries significant safety risks including nausea, hypertension, and priapism.

EC50 (Human Mc1r Ki):

1.2 nM

EC50 (Human Mc5r Ki):

1.0 nM

EC50 (Human Mc3r Ki):

1.1 nM

EC50 (Human Mc4r Ki):

2.1 nM

Source:

Wikberg JES, et al. Pharmacol Res. 2000;42(5):393–420. PubChem CID 92432.DOI

Clinical Development:

NCT00005114

References

ChEMBL:

CHEMBL363210

PubChem:

PubChem

Literature:

FDA Warning Letters: Melanotan II (unapproved drug); WADA Prohibited List: Melanotan II (S2 hormone modulator)

Disclaimer:

Melanotan II is NOT FDA-approved. The FDA has issued multiple warning letters to companies illegally selling Melanotan II as an unapproved new drug. It is also listed on the WADA Prohibited List as a banned substance in sport. This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Melanotan-1 Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Retatrutide,Tirzepatide,Semaglutide,Cynomorium Songaricum Extract,Bull Penis Powder,Deer Penis Extract

Location:
Hefei, Provincia de Anhui

Year of Establishment:
2026

Inquiry History

19 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	ACE031, ACVR2B CAS 75921-69-6 99.9% White powder qiancheng	500	Dec 16, 2023
China	High Purity Melanotan -1 Peptide CAS 75921-69-6 Lyophilized powder 10mg/vial 10vials/box	1 MT	Jun 29, 2026
United States	mt1 and cjc 1925 with ipmorline and GHKCU and KLOW	20 MT	Oct 6, 2026
Poland	Retatrutide 50mg lyophilized powder in stock	50 MG	Feb 20, 2026
Thailand	Melanotan 1	1 PCS	Feb 7, 2026
United States	MT1	5 MG	Nov 12, 2024
Germany	Melanotan	2 G	Sep 16, 2026
United States	Melanotan 1	20 MG	Jul 1, 2026
Denmark	Melanotan 1	10 MG	Jun 1, 2026
Denmark	Melanotan - 1	10 PCS	May 31, 2026
United States	Melanotan 1	6 MT	Apr 19, 2026
United States	Melanotan 1	10 MG	Apr 2, 2026
United States	Melanotan 1	10 G	Apr 1, 2026
Pakistan	Melanotan-1	20 MG	Jan 21, 2026
Sweden	Melanotan 1	1 KG	Jul 28, 2025
United Kingdom	Melanotan	1 KG	Sep 17, 2026
Australia	Melanotan 1	8 MT	Sep 15, 2024
China	High Purity Melanotan -1 Mt1 Peptide CAS 75921-69-6 Lyophilized powder 10mg/vial 10vials/box	1 MT	Jun 29, 2026
China	Lyophilized Peptide 99.9% Purity Melanotan I Powder Melanotan 1 Mt1 CAS 75921-69-6	1 MT	Jun 29, 2026

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