 Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > TB500 for Sale > TB500(20mg)

TB500(20mg)

Name: TB500(20mg)
Brand: Pharma;Conutrix
SKU: pr2610081508
Price: 10 USD
Availability: InStock

35 Inquiries

Unit Price:

$10/UNIT FOB

Get Latest Price 

CAS No.:

885340-08-9

Grade:

Pharmaceutical Grade

Content:

99%

Port:

tianjin

Brand:

Pharma;Conutrix

Packaging:

10 vials/box

Price valid (until):

2026-11-20

Contact Supplier

 Chat Now

Anhui Ruibang Trading Co., Ltd

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Retatrutide,Tirzepatide,Semaglutide,Cynomorium Songaricum Extract,Bull Penis Powder,Deer Penis Extract

 Visit Store

Product Description
Seller Information
Inquiry History

Description
Product Detail
. Product Overview

Alprostadil, also known as Prostaglandin E1 (PGE1), is a high-purity synthetic bioactive prostaglandin molecule with pharmaceutical-grade specifications. Though not a traditional amino-acid peptide, it exhibits peptide-like high biological activity and precise signaling regulation, widely classified as a specialty therapeutic biomolecule. Produced via standardized synthetic processes with ≥99% HPLC purity, this stable small-molecule compound features ultra-high biological availability, consistent batch repeatability and low systemic irritation. As a potent EP receptor agonist, Alprostadil specializes in vascular dilation, microcirculation activation, smooth muscle relaxation and anti-platelet aggregation. It is extensively applied in vascular function research, peripheral circulation repair, microvascular lesion conditioning and high-end pharmaceutical raw material formulation development.

2. Basic Specifications

Product Name: Alprostadil Pharmaceutical Grade

Full Name: Prostaglandin E1 (PGE1)

CAS Number: 745-65-3

Molecular Weight: 354.48 Da

Purity: ≥99.0% (HPLC)

Appearance: White sterile lyophilized powder

Solubility: Soluble in sterile water and aqueous solvent

Core Feature: Potent microcirculation activator & vascular smooth muscle regulator

Grade Standard: Pharmaceutical raw material grade, low endotoxin, heavy metal compliant

Storage: -20°C sealed, dry and protected from light

Shelf Life: 24 months under standard storage conditions

3. Mechanism of Action

Alprostadil exerts targeted vascular and tissue regulation by selectively binding to EP prostanoid receptors distributed on vascular smooth muscle, endothelial cells and peripheral tissues. It activates intracellular adenylate cyclase, elevates cAMP levels and reduces intracellular calcium concentration, triggering continuous vascular smooth muscle relaxation and systemic microvascular dilation. Meanwhile, it effectively inhibits platelet adhesion and aggregation, improves blood rheology, and eliminates microcirculation stasis and hypoxic damage.

Different from common vasodilators with transient efficacy, Alprostadil delivers dual vascular protection and metabolic optimization. It repairs damaged vascular endothelial function, improves peripheral tissue oxygen and nutrient supply, blocks inflammatory cascades caused by microcirculation disorders, and achieves long-term stabilization of vascular physiological function without endocrine disturbance or drug resistance.

4. Core Benefits & Applications

Microcirculation Activation: Dilates peripheral microvessels, improves blood flow velocity, relieves tissue ischemia and hypoxia, and repairs microcirculation dysfunction caused by aging and vascular sub-health.

Vascular Endothelial Repair: Protects vascular endothelial cells, reduces endothelial inflammatory damage, improves vascular elasticity, and delays peripheral vascular tissue degeneration.

Anti-Thrombotic & Blood Regulation: Inhibits abnormal platelet aggregation, optimizes blood rheological properties, and reduces the risk of microvascular stasis and occlusion.

Smooth Muscle Regulation: Relaxes cavernosal and peripheral smooth muscle, improves local blood perfusion, and supports physiological tissue function recovery.

Professional Research Use: High-purity API for vascular pharmacology, microcirculation mechanism research, endothelial repair study and pharmaceutical formulation development.

5. Advantages of 99% Pharmaceutical-Grade Alprostadil

Precise EP receptor targeting: Specific binding to prostanoid receptors, accurate vascular regulation with minimal systemic side effects

Dual dilation & repair efficacy: Combines rapid microcirculation activation and long-term endothelial repair, superior to single-effect vasodilators

Small-molecule high permeability: Ultra-low molecular weight ensures fast tissue penetration and high bioavailability

≥99% HPLC ultra-high purity, strict single impurity control, zero batch difference for synthetic prostaglandin biomolecule

Low endotoxin and ultra-low heavy metals, fully compliant with pharmaceutical raw material standards, stable activity and formulation compatibility

6. Safety & Usage Features

Alprostadil is a high-safety pharmaceutical biomolecule with reliable biological tolerance. It features mild physiological vascular regulation, no hormone interference, no cumulative toxicity and no drug dependence. Standard cyclic use safely optimizes microcirculation, repairs endothelial damage and improves tissue hypoxia status, suitable for long-term vascular sub-health conditioning and high-standard biomedical research applications.
Items Specifications
ECHEMI Editorial Reference

TB 500 is a synthetically made version of TB4 that facilitates healing and recovery by helping build new blood vessels, muscle tissue fibers, blood cells, and facilitating cell migration. It acts on the muscular system and has anabolic properties. TB 500 is used primarily for race animals (horses and dogs).
Basic Info

Product Name:
TB500

Other Name:
TB500 fragment;L-Glutamine, N-acetyl-L-leucyl-L-lysyl-L-lysyl-L-threonyl-L-α-glutamyl-L-threonyl-;Thymosin Beta 4 Peptide Peptides Tb500 2mg/Vials 5mg/Vials;TB500 fragment acetate;TB500 Thymosin Beta 4 (TB4);Ac-LKKTETQ;Thymosin β4 TB500;TB500(Thymosin B4 AceTate) 5MG 10MG

CAS No.:
885340-08-9

Molecular Formula:
C38H68N10O14

InChIKeys:
ADKDNDYYIZUVCZ-HLXZCORBNA-N

Molecular Weight:
889.02

EC Number:
232-660-2

Color/Form:
White to Off-White

Categories:
Bulk Drug Intermediates

Characteristics

Density:
1.281±0.06 g/cm3(Predicted)

Boiling Point:
1405.0±65.0 °C(Predicted)

PKA:
3.20±0.10(Predicted)

Research

Class:
Actin-sequestering protein / 43-amino-acid peptide

Status:
Research compound — Not FDA approved (investigational: RGN-259 for dry eye / neurotrophic keratitis)

Mechanism:
A naturally occurring 43-amino-acid peptide (Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH) that binds G-actin (sequesters monomeric actin), preventing F-actin polymerization. Promotes cell migration, angiogenesis, wound healing, and anti-inflammatory responses via integrin-linked kinase (ILK) and HIF-1α/VEGF pathways. TB-500 is the synthetic fragment Ac-LKKTETQ (MW ~895) often sold under this CAS.

Activity note:
Thymosin Beta-4 is an actin-binding protein, not a receptor agonist. Functional activity is measured by actin sequestration (Kd ~0.7–1 μM) and cell migration assays, not EC₅₀.

Source:
Goldstein AL, et al. Vitam Horm. 2003;66:257–296. RegeneRx RGN-259 clinical program.DOI

Clinical Development:
NCT02974907; NCT02600429; NCT00376974

References

DrugBank:
DB04951

PubChem:
PubChem

UNII:
549LM7U24W

Literature:
PubMed: Goldstein AL et al. (2003) — Review; ClinicalTrials.gov: ARISE-1 (NCT02974907)

Disclaimer:
Thymosin Beta-4 (TB-500) is NOT FDA-approved for human therapeutic use. RGN-259 (Tβ4 ophthalmic solution) is an investigational drug not yet approved. TB-500 sold on research-chemical marketplaces is a synthetic fragment and is not an approved medicine. This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.
Seller Information

Business Type:
Trader

Main Products:
Retatrutide,Tirzepatide,Semaglutide,Cynomorium Songaricum Extract,Bull Penis Powder,Deer Penis Extract

Location:
Hefei, Provincia de Anhui

Year of Establishment:
2026

Inquiry History

35 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	TB500 99% White powder Beta-4 CAS 885340-08-9 powder Custom peptides	1000	Oct 30, 2023
United States	TB 500	150 MG	Apr 8, 2026
United States	China Origin TB500 2mg/5mg/10mg Lyophilized Powder for the Wound Repair Research	1 G	Mar 26, 2026
United States	TB500	100 MG	Feb 27, 2026
Germany	TB 500	1 KG	Feb 8, 2026
Portugal	Tb 500	10 MT	Aug 7, 2024
France	TB500	1 KG	Mar 27, 2024
United States	TB500	1 G	Jan 27, 2024
Morocco	PEPTIDES	100 MG	Sep 16, 2026
Brazil	TB-500	1 G	Jun 18, 2026
Canada	TB 500	1 KG	May 8, 2026
United States	TB 500	20 G	Feb 23, 2026
Brazil	alejandro	300 PCS	Feb 19, 2026
United States	TB500 10mg	1 MT	Oct 20, 2025
United States	Tesomorelin	1 KG	Aug 8, 2025
Italy	TB500	1000 MG	Dec 30, 2024
Netherlands	tb500	1	Dec 16, 2024
New Zealand	TB500	100 MG	Jun 24, 2024
Germany	High Purity 99% Tb-500 5mg TB 500 Peptide TB500	1 MT	Oct 19, 2023
United States	High Purity 99% Tb-500 5mg TB 500 Peptide TB500	10 MT	Oct 12, 2023

Go to Page

Post an enquiry for this product

More Choices Find All Products for Sale 

Product Name	Grade / Content	Price	Supplier Name	Details
Wholesale price Factory price top quality sample order TB-500	Pharmaceutical Grade/99	$68.79-85.98/UNIT FOB	Shandong Changxu Trade CO.,LTD	Inquiry
KLOW OEM Available \| Metabolic Wellness Research	Pharmaceutical Grade/99	$188-212/UNIT FOB	Hulong Biotechnology Co., Ltd	Inquiry
TB500	Pharma Grade/99	$28/KG EXW	DAHAI BIOCHEM LTD	Inquiry
TB4 Frag 17-23, TB500, 885340-08-9	Chemical Grade/98	$150-180/G FOB	cellmano peptide	Inquiry
TB500	Reagent Grade/99	$1/KG EXW	Maintain Biotech Co.Ltd	Inquiry

TB500(20mg)

Product Description

Seller Information

Inquiry History

. Product Overview

2. Basic Specifications

3. Mechanism of Action

4. Core Benefits & Applications

5. Advantages of 99% Pharmaceutical-Grade Alprostadil

6. Safety & Usage Features

More Choices Find All Products for Sale 

Related Searches

More from this Seller

Items	Specifications