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Home > Organic Chemistry > Alcohols, Phenols, Phenol Alcohols > 2-Butyne-1,4-diol for Sale > 2-Butyne-1,4-diol High Purity Organic Intermediate CAS 110-65-6 Research Grade Reagent for Pharmaceutical and Material Synthesis
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2-Butyne-1,4-diol High Purity Organic Intermediate CAS 110-65-6 Research Grade Reagent for Pharmaceutical and Material Synthesis

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Unit Price:

$50-55/KG FOB

Get Latest Price
CAS No.:

110-65-6

Grade:

Reagent Grade

Content:

99%

Port:

qingdao

Brand:

//

Packaging:

1g/vial, 5g/vial, 25g/vial, 100g/vial

Sample Available:

Yes

Price valid (until):

2026-11-13

Company Type:
Trader
Location:
China
Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
7 days
Qualification:
Main Products:

Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    —— Product Specifications ——

    Shop 2-Butyne-1,4-diol High Purity Organic Intermediate CAS 110-65-6 Research Grade Reagent for Pharmaceutical and Material Synthesis-Detailed Image 1

    —— Product Detail ——




                    • Product Overview

                      2-Butyne-1,4-diol (butynediol) is an organic compound with the molecular formula C₄H₆O₂ and molecular weight of 86.09 g/mol. This colorless to light yellow crystalline powder is a valuable intermediate in pharmaceutical, agrochemical, and material science research. The compound features two hydroxyl groups and a carbon-carbon triple bond.

                      Synthetic Process

                      • Reppe Synthesis: Acetylene reacts with formaldehyde under pressure in the presence of a copper catalyst to yield 2-butyne-1,4-diol

                      • Purification: The crude product is purified by distillation or recrystallization

                      • Quality Control: The final product is analyzed to ensure ≥98.0% purity by GC

                      Mechanism of Action

                      • Hydroxyl Reactivity: The two hydroxyl groups can be converted to esters, ethers, and other derivatives

                      • Alkyne Reactivity: The triple bond can participate in addition, hydrogenation, and coupling reactions

                      • Hydrogen Bonding: The diol structure enables hydrogen bonding and self-assembly

                      Research Applications & Market Significance

                      • Pharmaceutical Research: Building block for drug discovery programs

                      • Electroplating: Used as a brightener in nickel electroplating baths

                      • Polymer Chemistry: Monomer for the preparation of functional polymers and polyurethanes

                      • Agrochemical Synthesis: Intermediate for pesticide development

                      Quality Specifications

                      • Purity: ≥98.0% determined by GC

                      • Melting point: 54-57°C

                      • Boiling point: 238-240°C

                      • Loss on drying: ≤0.5%

                      • Storage: 2-8°C, sealed, protected from light

                      • Stable for 24 months when properly stored

                      Packaging & Shipping

                      • Research quantities: 100g, 500g amber glass bottles

                      • Bulk quantities: 1kg, 5kg fiber drums

                      • Shipped at ambient temperature



    — C ompany Profile ——


     ,

    Shop Amberlite IR-120 Cation Exchange Resin Sodium Form CAS 9002-23-7 High Purity Strong Acid Cation Exchange Resin for Water Softening, Demineralization,-Detailed Image 2

    Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

    Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

    We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

    To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.

    Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.

     

    Shop Amberlite IR-120 Cation Exchange Resin Sodium Form CAS 9002-23-7 High Purity Strong Acid Cation Exchange Resin for Water Softening, Demineralization,-Detailed Image 3

    Shop Amberlite IR-120 Cation Exchange Resin Sodium Form CAS 9002-23-7 High Purity Strong Acid Cation Exchange Resin for Water Softening, Demineralization,-Detailed Image 4 

    —— Q&A ——

    Q1: How to confirm the product quality before placing orders?
    A: By sending you available samples. Or if you have special requirements for the goods, we can prepare samples according to your requirements for confirmation.

    Q2: Can you supply free samples?
    A: Yes, we can provide a free sample, but the shipping cost will be paid by the customers. You can either pay the shipping cost or arrange a courier to collect the samples.

    Q3: How do you treat quality complaints?
    A: All our products are strictly tested by our QC and confirmed by QA; unqualified material will not be released to customers. If any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.

    Q4: What is your MOQ? Is there a discount?
    A: For highvalue products, our MOQ starts from 1g and generally starts from 10g. For other lowprice products, our MOQ starts from 100g and 1kg.
    Q: Is there a discount?
    A: Yes, for larger quantities, we always support with better prices.

    Q5: How to start orders or make payments?
    A: You can send us your Purchase Order (if your company has one), or just send a simple confirmation by email or via Trade Manager. We will then send you a Proforma Invoice with our bank details for your confirmation, and you can make payment accordingly. If you have other preferred payment methods, we are open to discussion and negotiation.



    ECHEMI Editorial Reference
    yellow solidChEBI: A butynediol that is but-2-yne substituted by hydroxy groups at positions 1 and 4.White to light-brown solid or brownish-yellow aqueous solution. Solid sinks and mixes with water.
    1,4-butynediol appears as white to light-brown solid or brownish-yellow aqueous solution. Solid sinks and mixes with water. (USCG, 1999)|Liquid; OtherSolid; OtherSolid, Liquid|YELLOW SOLID IN VARIOUS FORMS.
    1,4-butynediol appears as white to light-brown solid or brownish-yellow aqueous solution. Solid sinks and mixes with water. (USCG, 1999)|But-2-yne-1,4-diol is a butynediol that is but-2-yne substituted by hydroxy groups at positions 1 and 4.

    Certificates
    • 2-Butyne-1,4-diol High Purity Organic Intermediate CAS 110-65-6 Research Grade Reagent for Pharmaceutical and Material Synthesis Certificates 1 TDS

    Basic Info
    Product Name:

    2-Butyne-1,4-diol

    Other Name:

    2-Butyne-1,4-diol;1,4-Butynediol;Butynediol;Bis(hydroxymethyl)acetylene;2-Butynediol;1,4-Dihydroxy-2-butyne;NSC 834

    CAS No.:

    110-65-6

    Molecular Formula:

    C4H6O2

    InChIKeys:

    InChIKey=DLDJFQGPPSQZKI-UHFFFAOYSA-N

    Molecular Weight:

    86.09

    Exact Mass:

    86.09

    BRN:

    1071237

    EC Number:

    203-788-6

    UNII:

    AXH202FPQM

    ICSC Number:

    1733

    NSC Number:

    834

    UN Number:

    2716

    DSSTox ID:

    DTXSID4021921

    Color/Form:

    Plates from benzene and ethyl acetate|White, orthorhombic crystals|WHITE TO LIGHT YELLOW|Yellow scaley solid at 20 °C and 1,013 hPa

    HScode:

    29053980

    Characteristics
    PSA:

    40.5

    XLogP3:

    -0.73

    Appearance:

    slightly brown Crystalline Platelets or Flakes

    Density:

    1.1

    Melting Point:

    58 °C

    Boiling Point:

    238 °C @ Press: 760 Torr

    Flash Point:

    306 °F

    Refractive Index:

    1.4804

    Water Solubility:

    H2O: 3740 g/L (20 ºC)

    Storage Conditions:

    Refrigerator

    Vapor Pressure:

    <0.1 mm Hg ( 55 °C)

    Vapor Density:

    Relative vapour density (air = 1): 3.0

    Toxicity:

    Oral-Rat LD50: 104 mg/kg; Oral-Mouse LD50: 105 mg/kg

    Flammability characteristics:

    Inflammable in case of open flame, high temperature, oxidant; burning produces irritating smoke

    Explosive limit:

    Explosive reaction with traces of alkalies, alkali earth hydroxides, halide salts, strong acids, mercury salts plus strong acids.

    Henrys Law Constant:

    Henry's Law constant = 1.684X10-11 atm-cu m/mol at 25 °C (est)

    Experimental Properties:

    SOLN IS STRAW TO AMBER COLOR|Hydroxyl radical reaction rate constant = 3.38X10-11 cu cm/molec-sec at 25 °C (est)

    Air and Water Reactions:

    Soluble in water.

    Reactive Group:

    Alcohols and Polyols

    Reactivity Profile:

    Pure BUTYNEDIOL is non-explosive. Small amounts of certain impurities-alkali hydroxides, alkaline earth hydroxides, halides-may cause explosive decomposition upon distillation. Butynediol should not be treated with basic catalysts in the absence of a solvent at room temperature, and its stability is less with elevated temperatures. In strong acids, contamination with mercury salts can also result in violent decomposition. [NFPA 491M 1991].

    Autoignition Temperature:

    335 °C

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 3, Oral

    Acute toxicity - Category 4, Dermal

    Skin corrosion, Sub-category 1B

    Skin sensitization, Category 1

    Acute toxicity - Category 3, Inhalation

    Specific target organ toxicity – repeated exposure, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H301 Toxic if swallowed

    H312 Harmful in contact with skin

    H314 Causes severe skin burns and eye damage

    H317 May cause an allergic skin reaction

    H331 Toxic if inhaled

    H373 May cause damage to organs through prolonged or repeated exposure

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P272 Contaminated work clothing should not be allowed out of the workplace.

    P271 Use only outdoors or in a well-ventilated area.

    Response

    P301+P316 IF SWALLOWED: Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P330 Rinse mouth.

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P317 Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

    P363 Wash contaminated clothing before reuse.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P316 Get emergency medical help immediately.

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P333+P317 If skin irritation or rash occurs: Get medical help.

    P319 Get medical help if you feel unwell.

    Storage

    P405 Store locked up.

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Separated from incompatible materials. See Chemical Dangers. Cool. Store in an area without drain or sewer access.The storage temperature should be kept below 40 deg C and storage times longer than a few months should be avoided because the butynediol flakes tend to set up.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

    Location:

    RONGSHENG BEIYUANDAJIE 9, LICHENG DISTRICT,JINAN, SHANDONG CHINA

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7 days

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2022

    Jinan Topfull Chemical Co., Ltd. is a global chemical Industrial and focuses on advanced chemical technology. Specialized in Cosmetic materials, water treatment, fine chemicals and so on. We are looking forward to working together with the people of all circles at home and abroad to seek common development!
  • Inquiry History
    2 Inquiries
    Country Product Purchase Quantity Date Posted
    Russia

    2-Butyne-1.4-diol

    1 KG Jul 15, 2024
    United States

    2-butyne-1, 4 diol flake

    45 KG Jan 1, 2025
    Post an enquiry for this product
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