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Hot Sale 99% Purity CAS 4759-48-2 Cosmetics Raw Powder Isotretinoin

Name: Hot Sale 99% Purity CAS 4759-48-2 Cosmetics Raw Powder Isotretinoin
Brand: Hot Sale 99% Purity CAS 4759-48-2 Cosmetics Raw Po
SKU: pr2610191084
Price: 120 USD
Availability: InStock

TDS 26 Inquiries

Unit Price:

$120-130/MT FOB

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CAS No.:

4759-48-2

Grade:

Cosmetics Grade

Content:

99%

Port:

shanghai

Brand:

Hot Sale 99% Purity CAS 4759-48-2 Cosmetics Raw Po

Packaging:

25kg/drum

Price valid (until):

2026-11-19

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Ou Sheng International Trading Limited

Company Type:

Trader

Location:

Hongkong, China

Payment Terms:

100% TT in advance

Average Lead Time:

15 days

Qualification:

Main Products:

nitric acid,sles,xylene,aniline

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Product Details
Seller Information
Inquiry History

Description

Hot Sale 99% Purity CAS 4759-48-2 Cosmetics Raw Powder Isotretinoin

Introduction
Isotretinoin is a synthetic derivative of vitamin A, belonging to the retinoid class of medications. It is most commonly available in oral capsule form, though topical formulations (such as gels or creams) exist for specific skin conditions. A key characteristic of isotretinoin is its ability to target multiple pathways involved in acne development: it reduces the size and activity of sebaceous glands (lowering oil production), prevents the clogging of hair follicles by normalizing skin cell turnover, and exerts anti-inflammatory effects to reduce redness and swelling associated with acne lesions. Importantly, it is a potent medication with strict usage guidelines, as it carries significant risks if used improperly-particularly a high risk of birth defects if taken during pregnancy, requiring rigorous contraception measures for eligible patients.
Applications
Isotretinoin is primarily used in the medical field for the treatment of severe, recalcitrant acne vulgaris-specifically nodular or cystic acne that has not responded to other treatments like oral antibiotics or topical therapies. Its ability to address the root causes of acne makes it highly effective, often leading to long-term remission of symptoms even after treatment completion. Beyond acne, it has off-label uses for other severe skin conditions, such as hidradenitis suppurativa (a chronic inflammatory skin disease affecting sweat glands) and severe rosacea that is unresponsive to standard treatments. In rare cases, it may also be used to manage certain types of skin cancer (like cutaneous T-cell lymphoma) under close medical supervision. Due to its potential side effects (including dry skin, liver enzyme elevation, and mood changes), isotretinoin is only prescribed by healthcare providers experienced in its use, with regular monitoring of patients throughout the treatment course.

Detailed Photos

Items	Specifications

Product Name:	Isotretinoin
Testing Standard:	USP Standard
Country of Origin:	China	Packing Size:	25kgs/Drum
Lot Quantity:	50kgs
ITEMS	SPECIFICATIONS		TEST RESULTS
Appearance	Yellow or Orange Crystalline Powder		Orange Crystalline Powder
Solubility	Sparingly Soluble in Ethanol, Isopropyl Alcohol, and in Polyethylene Glycol, Practically Insoluble in Water.		Complies
Identification	1, The IR Absorption Spectrum Should Correspond with Reference Spectrum		Complies
	2, Should Exhibits Maximum Absorption at 354nm		Complies
Loss on Drying	≤0.5%		0.1%
Residue on Ignition	≤0.1%		0.04%
Heavy Metals	≤0.002%		<0.002%
Related Substances	Tretinoin≤1.0%		0.1%
Assay	98.0%~102.0% ( Calculated on the Dried Basis )		99.7%

ECHEMI Editorial Reference

Isotretinoin(13-cis-Retinoic acid) is a medication used for the treatment of severe acne. It was first developed to be used as a chemotherapy medication for the treatment of brain cancer, pancreatic cancer and more.Target: RAR/RXRIsotretinoin has been the most effective and long-lasting drug for the treatment of severe acne for more than 30 years and can achieve long-term remission in 70-80% of patients after a single course. The new evidence-based European S3-guideline recommends the us
Retinoic acid is a retinoid consisting of 3,7-dimethylnona-2,4,6,8-tetraenoic acid substituted at position 9 by a 2,6,6-trimethylcyclohex-1-en-1-yl group (geometry of the four exocyclic double bonds is not specified). It has a role as a human metabolite. It is a retinoid and an alpha,beta-unsaturated monocarboxylic acid. It is a conjugate acid of a retinoate.

Certificates

Basic Info

Product Name:

Isotretinoin

Other Name:

Retinoic acid,13-cis-;13-cis-Retinoic acid;Neovitamin A acid;13-cis-Vitamin A acid;Ro 4-3780;13-cis-β-Retinoic acid;Isotretinoin;(13Z)-Retinoic acid;Accutane;Roaccutane;AGN 190013;Roaccutan;Accure;13-RA;Isotrex;IsotrexGel;cis-Retinoic acid;Absorica;Amnesteem;Claravis;Roacutan

CAS No.:

4759-48-2

Molecular Formula:

C20H28O2

InChIKeys:

InChIKey=SHGAZHPCJJPHSC-XFYACQKRSA-N

Molecular Weight:

300.44

Exact Mass:

300.44

EC Number:

225-296-0

HScode:

2942000000

Categories:

Anti-sebum

Characteristics

PSA:

37.3

XLogP3:

5.66

Appearance:

Yellow-orange to orange Fine Crystalline Powder

Density:

1.0±0.1 g/cm3

Melting Point:

174-175 °C

Boiling Point:

462.8°C at 760 mmHg

Flash Point:

350.6±11.0 °C

Refractive Index:

1.556

Water Solubility:

H2O: insoluble

Storage Conditions:

−20°C

Vapor Pressure:

1.02X10-7 mm Hg at 25 °C (est)

Toxicity:

LD50 (20 day) in mice, rats (mg/kg): 904, 901 i.p.; 3389, >4000 orally (Kamm)

PKA:

See More Isotretinoin Properties 

Hazard Identification

Classification of the substance or mixture

Reproductive toxicity, Category 1B

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H360 May damage fertility or the unborn child H400 Very toxic to aquatic life H410 Very toxic to aquatic life with long lasting effects
Prevention	P203 Obtain, read and follow all safety instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P273 Avoid release to the environment.
Response	P318 IF exposed or concerned, get medical advice. P391 Collect spillage.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

PRECAUTIONS FOR CYTOTOXIC AND HAZARDOUS DRUGS:/ Facilities (eg, shelves, carts, counters, and trays) for storing hazardous drugs are designed to prevent breakage and to limit contamination in the event of leakage. Bins, shelves with barriers at the front, or other design features that reduce the chance of drug containers falling to the floor should be used. Hazardous drugs requiring refrigeration should be stored separately from nonhazardous drugs in individual bins designed to prevent breakage and to contain leakage.

See More Isotretinoin Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
nitric acid,sles,xylene,aniline

Location:
UNIT 903, 9/F., CAMERON COMM CENTRE, 458-468 HENNESSY ROAD, CAUSEWAY BAY HONG KONG

Payment Terms:
100% TT in advance

Average lead Time:
15 days

Total Annual Revenue:
$5 million-$10 million

Total Employees:
51-100

Year of Establishment:
2026

We are a professional exporter of industrial chemical solvents and mining‑use chemicals.

We supply a wide range of industrial solvents for coating, printing, cleaning and manufacturing industries. Our mining‑chemical products include flotation collectors, frothers, flocculants and other reagents for mineral processing and mine wastewater treatment.

With rich experience in chemical export, we provide stable‑quality goods, customized packaging and complete export solutions. We sincerely welcome global customers for inquiries and long‑term cooperation.

Inquiry History

26 Inquiries

Country	Product	Purchase Quantity	Date Posted
Croatia	Isotretinoin 4759-48-2	10 G	Nov 18, 2023
Germany	Isotretinoin CAS: 4759-48-2	50000 KG	Sep 22, 2026
United States	Isotretinoin	300 PCS	Oct 20, 2026
Denmark	Isotretinoin	5 G	Sep 9, 2026
New Zealand	Accutane powder	10 G	Aug 9, 2026
Italy	Isotretinoin	10 G	Jul 16, 2026
United States	Isotretnoin	1 MT	Jul 10, 2026
United States	isotretinoin	1 KG	Apr 8, 2026
Canada	Isotretinoin	50 G	Feb 19, 2026
United States	Isotretinoin	100 G	Jan 27, 2026
Czech	Isotretinoin	30 G	Dec 17, 2025
Russia	Isotretinoin Lidose 8 mg, 16 mg, 24 mg, 32 mg	500 KG	Nov 13, 2025
Czech	Isotretinoin	1 KG	Nov 8, 2025
Pakistan	Isotretinoin	10000 MG	Oct 25, 2025
Norway	Isotretinoin powder	10 G	Apr 13, 2025
Germany	Isotretinoin	1 KG	Jun 26, 2026
Germany	Api Powder Isotretinoin 98% Accutane ISOTRETINOIN API POWDER	10 G	Apr 3, 2026
Australia	isotretinoin	10 G	Mar 10, 2026
United States	Isotretinoin	1 MT	Mar 5, 2026
Denmark	Isotretinoin powder	20 G	Nov 21, 2025

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Hot Sale 99% Purity CAS 4759-48-2 Cosmetics Raw Powder Isotretinoin

Product Details

Seller Information

Inquiry History

Hot Sale 99% Purity CAS 4759-48-2 Cosmetics Raw Powder Isotretinoin

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

More Choices Find All Products for Sale 

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