Thymosin Alpha 1 High Grade Synthetic Lyophilized Peptide for Biochemical Lab Research
4474-91-3
Research Grade
99%
qingdao
5mg;10mg;15mg;20mg;30mg;40mg;50mg;100mg;500mg
2026-11-16
Cosmetics
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Product Details
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Seller Information
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DescriptionECHEMI Editorial ReferenceAngiotensin II human is a vasoconstrictor that acts on the AT1 and the AT2 receptor.
Solid
Ile(5)-angiotensin II is an angiotensin II that acts on the central nervous system (PDB entry: 1N9V). It has a role as a human metabolite. It is a tautomer of an Ile(5)-angiotensin II dizwitterion.|Angiotensin II is under investigation for the treatment of Sepsis, Septic Shock, Diabetes Mellitus, and Acute Renal Failure. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy. As of December 21, 2017 the FDA approved La Jolla Pharmaceutical's Giapreza (angiotensin II) Injection for Intravenouse Infusion for the indication of acting as a vasoconstrictor to increase blood pressure in adults with septic or other distributive shock. The novelty of the medication lies in the fact that it is the first and only use of synthetic human angiotensin II to help maintain body blood pressure. Shock is the inability to maintain blood flow to vital tissues and the potential resultant organ failure and death within hours, no matter young or o ld. As distributive shock is the most common type of shock in the inpatient setting and affects up to one third of patients in the intensive care unit, the FDA determined that there is a need for treatment options for critically ill hypotensive patients who do not adequately respond to currently available therapies.|Angiotensin ii is a Vasoconstrictor. The physiologic effect of angiotensin ii is by means of Vasoconstriction.|Therapeutic Angiotensin II is a synthetic form of the endogenous angiotensin II, a peptide hormone of the renin-angiotensin-aldosterone system (RAAS) that causes vasoconstriction and an increase in blood pressure, that may be used for the treatment of septic or other distributive shock. Upon administration, therapeutic angiotensin II binds to angiotensin II type 1 receptor on vascular smooth muscle cells which leads to Ca2+/calmodulin-dependent phosphorylation of myosin. This causes smooth muscle contraction and results in vasoconstriction and an increase in blood pressure. Therapeutic angiotensin II also increases blood pressure by stimulating the release of the steroid hormone aldosterone, which regulates the renal absorption of water and sodium.|An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME. The amino acid in position 5 varies in different species. To block VASOCONSTRICTION and HYPERTENSION effect of angiotensin II, patients are often treated with ACE INHIBITORS or with ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS.Research & Reference NoteThymosin Alpha 1 High Grade Synthetic Lyophilized Peptide for Biochemical Lab Research is listed on ECHEMI for industrial / laboratory sourcing. This listing is for industrial and laboratory research use. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.
Authoritative sourcesDisclaimer: This listing is for industrial and laboratory research use. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.
Reviewed by ECHEMI Scientific Review - Platform editorial review for research chemicals
Basic Info-
Product Name:
ANGIOTENSINII,HUMAN
Other Name:AngII;DRVYIHPF;TY-10721;ANGIOTENSIN-2;ANGIOTENSINII;ANTI-ANGIOTENSINII;ile(5)-angiotensini;[ILE5]-ANGIOTENSIN2;angiotensinii(mouse);[Ile5]angiotensinII
CAS No.:4474-91-3
Molecular Formula:C50H71N13O12
InChIKeys:CZGUSIXMZVURDU-JZXHSEFVSA-N
Molecular Weight:1046.18
Exact Mass:1045.534546
EC Number:2017-001-1
UNII:M089EFU921
DSSTox ID:DTXSID4036778|DTXSID30196288
NCI Thesaurus Code:C173802
ATC Code:C09|C - Cardiovascular system
Categories:
Characteristics-
PSA:
406.34000
XLogP3:2.34
Appearance:orange Powder
Density:1.4±0.1 g/cm3
Boiling Point:809.08°C (rough estimate)
Refractive Index:1.664
Water Solubility:soluble in water (25 mg/ml), and 5% Acetic Acid (1 mg/ml).
Storage Conditions:−20°C
Collision Cross Section:353.79 Ų [M+2H]2+ [CCS Type: DT, Method: stepped-field]|436.24 Ų [M+3H]3+ [CCS Type: DT, Method: stepped-field]|314.38 Ų [M+H]+ [CCS Type: DT, Method: stepped-field]
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Cosmetics
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Location:
Room 204, Unit 1, Building 3, Liming 1st District, Choujiang Subdistrict, Wenwu City, Jinhua City, China (Zhejiang) Pilot Free Trade Zone
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Year of Establishment:
2026
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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