Product Overview

Benzothiazole is an organic compound with the molecular formula C₇H₅NS and molecular weight of 135.19 g/mol. This colorless to light yellow liquid is a valuable heterocyclic intermediate in pharmaceutical, agrochemical, and material science research. The compound features a benzene ring fused to a thiazole ring.

Synthetic Process

• Condensation: N,N-Dimethylaniline reacts with sulfur at elevated temperature to form benzothiazole

• Purification: The crude product is purified by distillation under reduced pressure

• Quality Control: The final product is analyzed to ensure ≥96.0% purity by GC

Mechanism of Action

• Heterocyclic Reactivity: The nitrogen and sulfur atoms provide unique electronic properties

• Pharmaceutical Relevance: Benzothiazole derivatives exhibit various biological activities

• Flavor Properties: Contributes to the characteristic aroma of certain foods

Research Applications & Market Significance

• Pharmaceutical Research: Building block for drug discovery programs, including pramipexole intermediates

• Agrochemical Synthesis: Intermediate for pesticide development

• Dye Industry: Intermediate for the preparation of dyes and pigments

• Flavor and Fragrance: Used as a flavoring agent (FEMA No. 3256)

Quality Specifications

• Purity: ≥96.0% determined by GC

• Boiling point: 231°C

• Density: 1.238 g/mL at 25°C

• Refractive index: n²⁰/D 1.642

• Flash point: >110°C

• Storage: 2-8°C, sealed, protected from light

• Stable for 24 months when properly stored

Packaging & Shipping

• Research quantities: 25g, 100g amber glass bottles

• Bulk quantities: 500g, 1kg amber glass bottles

• Shipped at ambient temperature