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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Agomelatine for Sale > High quality Raw powder cas138112-76-2 Agomelatine, factory supply
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High quality Raw powder cas138112-76-2 Agomelatine, factory supply

GMP ISO COA 2 Inquiries

Unit Price:

$1.2/G FOB

Get Latest Price
CAS No.:

138112-76-2

Grade:

Pharmaceutical Grade

Content:

99.62%

Port:

qingdao

Brand:

Million

Packaging:

1g 10g 100g 1kg/bag 25kg/Cardboard Drum

Sample Available:

Yes

Price valid (until):

2055-06-09

Company Type:
Manufactory
Location:
China
Payment Terms:
L/C,100% TT in advance
Average Lead Time:
3 days
Qualification:
Main Products:

Avanafil,Tirzepatide,Semaglutide,Pregabalin,Nootropics,MT2

  • Product Details

  • Seller Information

  • Inquiry History

  • Description

    Shop Apixaban CAS 503612-47-3 high quality best service fast delivery large stock manufacturer-Detailed Image 1


    Shop Apixaban CAS 503612-47-3 high quality best service fast delivery large stock manufacturer-Detailed Image 2


    Why Choose Us ?

    1 、 Manufacturer supply, best price and service.

    2、 Safe fast delivery.

    3、 F ree sample.

    4、 Large stock.

    5、 Easy payment: bank transfer,  moneygram, paypal....

    6、 Good reputation, great feedback.

    7、 Customers worldwide:  Metrochem Api Pvt Ltd;Bdr Lifesciences Pvt.Ltd;Srini Chem;Eva Pharma;Pharmaffiliates Analytics&Synthetics(p)Ltd;....From India,Egypt,Canada ....


    -Packing&Shipping-

    Shop Apixaban intermediates 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one CAS 536760-29-9-Detailed Image 3


    Ship methods
    Special line
    Express By air
    By sea
    DHL/TNT/FeDex/UPS
    Delivery 7-15 days 3-10 days 3-5 days 10-30 days
    Service Door to door Door to door To airport To seaport
    Customs clearance No Possible Yes Yes

    -Company Profile-

    Shop Apixaban intermediates 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one CAS 536760-29-9-Detailed Image 4

    Shop Apixaban intermediates 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one CAS 536760-29-9-Detailed Image 5


    About us:

    Founded in 2012, Jinan Million Pharmaceutical Co., Ltd (Jinan Milin Pharmaceutical Co., Ltd) is a modern pharmaceutical enterprise guided by innovation. Million pharm has excellent research and development capabilities and complete industrial bases with international quality management system. It is dedicated to the research, development, production and customization of pharmaceuticals and advanced pharmaceutical intermediates.
     
       Jinan Million Pharmaceutical Co., Ltd has been focusing on the research of Cerebro-cardiovascular drugs, Central nervous system drugs, Anti-cancer drugs, Antibacterial drugs and others for 12 years; the products are: Apixab a n, Lurasidon e , Bexagliflozin, Vortioxetine, L OXO -292/Selpercatinib, Baricitinib and intermediates. Million has worked with reputable customers, like METROCHEM API PVT LTD; BDR LIFESCIENCES PVT.LTD; SRINI CHEM; EVA PHARMA; PHARMAFFILIATES ANALYTICS & SYNTHETICS (P) LTD; ....from India, Egypt, Canada...


    Jinan Million Pharmaceutical Co., Ltd has a 1,500㎡ R&D center in the Zhongguancun E Valley (Qihe) Incubator, equipped with complete test equipment, such as high-performance liquid chromatography, nuclear magnetic resonance spectrometer, liquid chromatography mass spectrometer, automatic polarimeter, etc., which can meet the needs of various  laboratory scale tests in different conditions. The pilot workshop is equipped with 50L and 100L glass reactors, high and low temperature equipment, etc., which can support organic chemical reactions at -100°C or 200°C. In addition, Million has a production site in Linyi city with many independent production lines, such as: production line of Apixabn intermediate 20 tons/year, production line of Lurasidon intermediate 10 tons/year, which can meet the commercial production of various products.
     
       The technical team is composed of high-level talents in major of pharmacy, bio-pharmaceutical or chemical synthesis, of which 10% has doctor’s degree and 15% has master’s degree. The team members are young and energetic with innovative spirit and willing to overcome obstacles.
     
       Jinan Million Pharmaceutical Co., Ltd adheres to the business philosophy of "dedication and innovation", insists on pioneering and innovating, constantly improves the quality system, and vigorously trains technical and management talents to build an elite team and serves customers better. Looking forward to cooperate with you for joint development and common progress.


    -Certification- Shop Apixaban intermediates 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one CAS 536760-29-9-Detailed Image 6

    ECHEMI Editorial Reference
    Agomelatine is a competitive antagonist of human and porcine serotonin (5-HT2C) receptors (pKi = 6.2 and 6.4, respectively) as well as human 5-HT2B receptors (pKi = 6.6). IC50 value: 6.2 (pKi, 5-HT2c); 6.6 (pKi, 5-HT2b)Target: 5-HT2C Receptor; 5-HT2B receptorIt is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor. Activation of 5-HT2C receptors by serotonin inhibits dopamine and norepinephrine release. Antagonism of 5-HT2C results in
    Solid
    Agomelatine is a member of acetamides.|Agomelatine is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression. Agomelatine was developed in Europe by Servier Laboratories Ltd. and submitted to the European Medicines Agency (EMA) in 2005. The Committee for Medical Products for Human Use (CHMP) recommended refusal of marketing authorization on 27 July 2006. The major concern was that efficacy had not been sufficiently shown. In 2006 Servier sold the rights to develop Agomelatine in the US to Novartis. The development for the US market was discontinued in October 2011. It is currently sold in Australia under the Valdoxan trade name.

    Certificates

    Basic Info
    Product Name:

    Agomelatine

    Other Name:

    Acetamide,N-[2-(7-methoxy-1-naphthalenyl)ethyl]-;N-[2-(7-Methoxy-1-naphthalenyl)ethyl]acetamide;S 20098;N-[2-(7-Methoxy-1-naphthyl)ethyl]acetamide;Agomelatine;Valdoxan;N-[2-(7-Methoxynaphthalen-1-yl)ethyl]acetamide;AGO 178;Thymanax

    CAS No.:

    138112-76-2

    Molecular Formula:

    C15H17NO2

    InChIKeys:

    InChIKey=YJYPHIXNFHFHND-UHFFFAOYSA-N

    Molecular Weight:

    243.30100

    Exact Mass:

    243.30

    UNII:

    137R1N49AD

    DSSTox ID:

    DTXSID3057642

    ATC Code:

    N06AX22|N - Nervous system

    HScode:

    2924199090

    Characteristics
    PSA:

    38.33000

    XLogP3:

    2.7

    Appearance:

    white solid

    Density:

    1.109g/cm3

    Melting Point:

    109-110 °C @ Solvent: Toluene, Hexane

    Boiling Point:

    478.8ºC at 760 mmHg

    Flash Point:

    243.4ºC

    Refractive Index:

    1.582

    Water Solubility:

    7.76e-03 g/L

    Collision Cross Section:

    156.3 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]

    Hazard Identification

    Classification of the substance or mixture

    Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H400 Very toxic to aquatic life

    Precautionary statement(s)
    Prevention

    P273 Avoid release to the environment.

    Response

    P391 Collect spillage.

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Avanafil,Tirzepatide,Semaglutide,Pregabalin,Nootropics,MT2

    Location:

    Room 1-2208, Lianhecaifu Square, No2177, Tianchen Road, Gaoxin District, Jinan City, Shandong Province, China

    Payment Terms:

    L/C,100% TT in advance

    Average lead Time:

    3 days

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2012

    Company Certificates
    • Jinan Million Pharmaceutical Co., Ltdbusiness license business license

    Founded in 2012, Jinan Million Pharmaceutical Co., Ltd (Jinan Milin Pharmaceutical Co., Ltd) is a modern pharmaceutical enterprise guided by innovation. Million pharm has excellent research and development capabilities and complete industrial bases with international quality management system. It is dedicated to the research, development, production and customization of pharmaceuticals and advanced pharmaceutical intermediates.
     
    Jinan Million Pharmaceutical Co., Ltd has been focusing on the research of Cerebro-cardiovascular drugs, Central nervous system drugs, Anti-cancer drugs, Antibacterial drugs and others for 12 years; the products are: Apixaban, Lurasidone, Bexagliflozin, Votioxitine, Loxo-292/Selpercatinib, Baricitinib and intermediates. Million has worked with reputable customers, like METROCHEM API PVT LTD; BDR LIFESCIENCES PVT.LTD; INCETPAT PHARM; SRINI CHEM; EVA PHARMA; PHARMAFFILIATES ANALYTICS & SYNTHETICS (P) LTD; ....from India, Egypt, Canada...



    Jinan Million Pharmaceutical Co., Ltd has a 1,500㎡ R&D center in the Zhongguancun E Valley (Qihe) Incubator, equipped with complete test equipment, such as high-performance liquid chromatography, nuclear magnetic resonance spectrometer, liquid chromatography mass spectrometer, automatic polarimeter, etc., which can meet the needs of various  laboratory scale tests in different conditions. The pilot workshop is equipped with 50L and 100L glass reactors, high and low temperature equipment, etc., which can support organic chemical reactions at -100°C or 200°C. In addition, Million has a production site in Linyi city with many independent production lines, such as: production line of Apixabn intermediate 20 tons/year, production line of Lurasidon intermediate 10 tons/year, which can meet the commercial production of various products.
     
    The technical team is composed of high-level talents in major of pharmacy, bio-pharmaceutical or chemical synthesis, of which 10% has doctor’s degree and 15% has master’s degree. The team members are young and energetic with innovative spirit and willing to overcome obstacles.
     
    Jinan Million Pharmaceutical Co., Ltd adheres to the business philosophy of "dedication and innovation", insists on pioneering and innovating, constantly improves the quality system, and vigorously trains technical and management talents to build an elite team and serves customers better. Looking forward to cooperate with you for joint development and common progress.

  • Inquiry History
    2 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Agomelatine

    30 G Apr 28, 2026
    Sweden

    Agomelatine

    25 G Feb 4, 2024
    Post an enquiry for this product
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