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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > TYRA-300 for Sale > Dabogratinib,TYRA-300 ,CAS NO.2800223-30-5 99%HPLC White to off-white powder_LYNA Bio
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Dabogratinib,TYRA-300 ,CAS NO.2800223-30-5 99%HPLC White to off-white powder_LYNA Bio

248 Inquiries

Unit Price:

$990-1000/G FOB

Get Latest Price
CAS No.:

2800223-30-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Brand:

LN

Packaging:

1kg\bag

Sample Available:

Yes

Price valid (until):

2026-11-26

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Urolithiasis B/Spermine Hydrochloride/ Apigenin/ Theacrine/FAA/OEA/PEA Theobromine/ Squid Ink Powder

  • Product Details

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  



    ProName: Dabogratinib,TYRA-300 ,CAS NO. 99%HPLC White to off-white powder_LYNA Bio

    CasNo:2800223-30-5
    Molecular Formula: C₂₅H₂₄Cl₂N₆O₃S
    Appearance: White to off-white powder
    Application: Healthcare Raw Materials and Nutrition...
    DeliveryTime: 3-7 days
    PackAge: 1kg/aluminum foil bag 25kg/drum
    Port: Main ports in China
    ProductionCapacity: 25-500 Kilogram/Month
    Purity: 99%HPLC
    Storage: Placed in Shade, dry, dark and low-tem...
    Transportation: By express, by air and by sea
    LimitNum: 1 Kilogram
    Heavy Metal: Heavy Metals
    Limited Quantity: 10ppm
    Valid Period: 24 months


    Dabogratinib (TYRA-300) is an orally bioavailable, highly selective FGFR3 tyrosine kinase inhibitor. It potently suppresses FGFR3 signaling and downstream ERK/MAPK pathway, inhibiting proliferation of FGFR3-altered tumors including urothelial carcinoma. It shows good kinome selectivity over other FGFR isoforms. Supplied as powder for laboratory preclinical research only, not approved for clinical treatment.


    NOTE: This product was prepared by chemical synthesis. Used only for research. Not for human use.

    Items Specifications
    CAS 2800223-30-5
    Shelf life >2 years if stored properly
    Shelf life powder
    Purity >99%  (or refer to the Certificate of Analysis)
    Transportation By Air
    Origin China
    Specification 1kg\bag
    Storage condition Dry, dark, room temperatur


      Advantage  


    1. Ultra-High Purity

    Each batch is synthesized and purified to >99% purity, ensuring reliable and reproducible results in sensitive experiments.


    2.Accurate Dosing & Consistency
    Our products are precisely weighed and vacuum-sealed under sterile conditions. Batch-to-batch consistency is rigorously maintained.


    3.Endotoxin-Free & Sterile Processing
    Manufactured in a cleanroom environment, our are free from endotoxins, microbial contamination, and other impurities that could interfere with cell-based or in vivo studies.

    Shop Dabogratinib,TYRA-300 ,CAS NO.2800223-30-5 99%HPLC White to off-white powder_LYNA Bio-Detailed Image 1


      Global Service


    Who We Serve


    -We proudly work with clients across North America, Europe, Asia, and Latin America, including:

    -Biotech and pharma firms

    -Research institutions & universities

    -Formulation startups

    -CDMOs and CRO partners

    Shop Dabogratinib,TYRA-300 ,CAS NO.2800223-30-5 99%HPLC White to off-white powder_LYNA Bio-Detailed Image 2


      About Us  


    We are a chemical manufacturer integrating production, processing and export, mainly dealing in pharmaceutical intermediates and various industrial chemicals. Since its establishment, the company adheres to the spirit of "integrity management, strict quality control, customer first", and has won praise from customers at home and abroad. We have also established an excellent professional sales team with rich international marketing experience, able to efficiently provide a range of products and professional services.


    With synthetic biology platform technology as the core, it conducts innovative research and development, mainly engaged in the research and development of recombinantly expressed pharmaceutical proteins. Its products include innovative drugs, APIs, pharmaceutical and green synthetic industrial enzymes, protein products, etc.


    At present, our company has realized the industrialization of a variety of biosynthetic products and has obtained cooperation orders from many well-known domestic and foreign pharmaceutical companies.

    Shop Dabogratinib,TYRA-300 ,CAS NO.2800223-30-5 99%HPLC White to off-white powder_LYNA Bio-Detailed Image 3

    \


      FQA


    1. How to make an order?

    Send me message and let me know what you need with quantity , then i will calculate to you.


    2. What's the lead time and shipping ways?

    We will delivery to the package by USPS, FEDEX, DHL paket and UPS express to you after receive your payment, it would take around 5-15 days to your address.

    ECHEMI Editorial Reference
    Dabogratinib(TYRA-300) , a 3-pyridylindazole analog, is a reversible and selective inhibitor of FGFR3 with an IC50 of 11 nM in Ba/F3 cells. It also exhibit potent activity in human bladder cancer cell lines harboring FGFR3 activating fusions or mutations.

    Basic Info
    Product Name:

    TYRA-300

    Other Name:

    TYRA-300;2,6-Diazaspiro[3.3]heptane, 2-[5-[5-[(1R)-1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]-2-pyridinyl]-6-(methylsulfonyl)-;(R)-5-(1-(3,5-Dichloropyridin-4-yl)ethoxy)-3-(6-(6-(methylsulfonyl)-2,6-diazaspiro[3.3]heptan-2-yl)pyridin-3-yl)-1H-indazole;TYRA-300(Dabogratinib);Tyra-300 99% Shaanxi Dideu Medichem

    CAS No.:

    2800223-30-5

    Molecular Formula:

    C25H24Cl2N6O3S

    InChIKeys:

    JOAFWIHZEBKYQK-OAHLLOKOSA-N

    Molecular Weight:

    559.47

    EC Number:

    610-261-8

    Characteristics
    Density:

    1.58±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

    Boiling Point:

    791.2±70.0 °C(predicted)

    PKA:

    11.87±0.40(predicted)

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Urolithiasis B/Spermine Hydrochloride/ Apigenin/ Theacrine/FAA/OEA/PEA Theobromine/ Squid Ink Powder

    Location:

    Room 1502, Unit 3, Building 2, Nanshan Garden, Jianye 2nd Road, Guodu Subdistrict, Chang'an District, Xi'an City, Shaanxi Province, P.R.China

    Total Employees:

    101-200

    Year of Establishment:

    2017

    LN is a chemical manufacturer integrating production, processing and export, mainly dealing in pharmaceutical intermediates and various industrial chemicals. Since its establishment, the company adheres to the spirit of "integrity management, strict quality control, customer first", and has won praise from customers at home and abroad. We have also established an excellent professional sales team with rich international marketing experience, able to efficiently provide a range of products and professional services.

    With synthetic biology platform technology as the core, it conducts innovative research and development, mainly engaged in the research and development of recombinantly expressed pharmaceutical peptides and proteins. Its products include innovative drugs, APIs, pharmaceutical and green synthetic industrial enzymes, functional peptides and protein products, etc.

    At present, our company has realized the industrialization of a variety of biosynthetic peptide products and has obtained cooperation orders from many well-known domestic and foreign pharmaceutical companies.

  • Inquiry History
    248 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    tesa,reta,ghkcu,bac water

    50 MT Oct 26, 2026
    China

    TYRA-300

    1 G Oct 26, 2026
    United States

    dabogratinib (tyra-300)

    1 G Oct 25, 2026
    United States

    Dabogratinib

    5 G Oct 24, 2026
    United States

    Dabogratinib

    1 G Oct 24, 2026
    Netherlands

    Tyra-300/dabogratinib

    1 G Oct 23, 2026
    Canada

    Tyra300

    6 G Oct 23, 2026
    Portugal

    TYRA 300

    100 G Oct 22, 2026
    United Kingdom

    Tyra300

    2 G Oct 21, 2026
    United States

    Tyra-300

    1 MT Oct 20, 2026
    South Africa

    Tyra 300

    19 G Oct 20, 2026
    Jordan

    tyra-300

    1 G Oct 19, 2026
    Germany

    TYRA-300

    5 MG Oct 19, 2026
    United States

    Tyra-300

    1 G Oct 18, 2026
    United Kingdom

    Tyra 300

    1 G Oct 17, 2026
    United Kingdom

    Tyra 300

    1 MT Oct 16, 2026
    Taiwan, China

    Tyra 300

    3 G Oct 16, 2026
    Singapore

    Dabogratinib, Tyra 300

    1 G Oct 15, 2026
    Norway

    Tyra 300

    6 G Oct 15, 2026
    United Kingdom

    Tyra300

    1  Oct 15, 2026
    Post an enquiry for this product
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