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Acetic acid 2-chloroethyl ester542-58-5

Name: Acetic acid 2-chloroethyl ester542-58-5
Brand: OORENT
SKU: pr2611061856
Price: 33 USD
Availability: InStock

Unit Price:

$33-34/MT FOB

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CAS No.:

542-58-5

Grade:

Pharmaceutical Grade

Content:

99.5%

Port:

shanghai

Brand:

OORENT

Packaging:

Vial/Bottle/Bag/Carton

Sample Available:

Yes

Price valid (until):

2026-12-06

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Payment Terms:

100% TT in advance

Average Lead Time:

10 days

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Details
Seller Information

Description

Product Detailv

1-fluoro-3-chloropropane Basic information

Product Name:	1-fluoro-3-chloropropane
Synonyms:	1-fluoro-3-chloropropane;1-chloro-3-fluoro-propane;Propane, 1-chloro-3-fluoro-;Propane, 1-chloro-3-fluoro- (6CI,8CI,9CI);1-fluoro-3-chloropane
CAS:	462-38-4
MF:	C3H6ClF
MW:	96.53
EINECS:
Product Categories:
Mol File:	462-38-4.mol

1-fluoro-3-chloropropane Chemical Properties

Boiling point	69.68°C (estimate)
density	1.0581 (estimate)
refractive index	1.3871
InChI	InChI=1S/C3H6ClF/c4-2-1-3-5/h1-3H2
InChIKey	PFDZQZAOZNELDX-UHFFFAOYSA-N
SMILES	C(Cl)CCF
EPA Substance Registry System	HCFC-271fa (462-38-4)

Safety Information

MSDS Information

1-fluoro-3-chloropropane Usage And Synthesis

Uses	1-fluoro-3-chloropropane is a hydrocarbon derivative and can be used as an intermediate in organic synthesis.

1-fluoro-3-chloropropane Preparation Products And Raw materials

MSDS Information

Provider	Language
1-Chloro-3-bromopropane	English
ACROS	English
SigmaAldrich	English
ALFA	English

1-Bromo-3-chloropropane Usage And Synthesis

Description	1-Bromo-3-chloropropane is a halogenated alkane compound containing one bromine atom and one chlorine atom in its structure. Due to the high electronegativity of halogens, the molecule of 1-Bromo-3-chloropropane is highly electrophilic and is easily attacked by electrophilic reagents such as nucleophilic reagents, Lewis acid, etc., which undergoes nucleophilic substitution reactions. The compound is relatively stable at room temperature, but is susceptible to elimination reactions at high temperatures or in the presence of strong acids or bases. In addition, prolonged exposure to air should be avoided because 1-Bromo-3-chloropropane molecules contain halogen atoms that are susceptible to reaction by oxygen and moisture in the air to produce products such as alcohols and aldehydes.
Chemical Properties	It is a clear and colorless liquid that is soluble in ethanol, ether, and chloroform but insoluble in water.
Uses	1-Bromo-3-chloropropane is used in the preparation active pharmaceutical ingredient intermediate such as gemfibrozil and reproterol. It is also involved in the preparation of cardiovascular diseases and analgesic drugs materials. It is utilized as a phase separation reagent for the isolation of ribonucleic acid (RNA) in high quality. It is considered as a replacement of chloroform in nucleic acid separations.
Preparation	The most common method for producing 1-Bromo-3-chloropropane is through the free-radical addition of anhydrous hydrogen bromide to allyl chloride. Alternatively, it can be prepared by reacting ethylene with methylene chlorobromide.
Definition	ChEBI: 1-Bromo-3-chloropropane (I-BCP or 109-70-6) is an organochlorine compound that can be used as a safer and equally effective alternative to chloroform. It serves as a phase-separation agent for the one-step method of RNA isolation from biological samples like animal and plant tissue. I-BCP can replace CHCl3 in RNA phase separations.
General Description	1-bromo-3-chloropropane appears as a colorless liquid. Insoluble in water and denser than water. May be toxic by inhalation, ingestion or skin absorption. Used to make pharmaceuticals and other chemicals.
Air & Water Reactions	Insoluble in water.
Reactivity Profile	Halogenated aliphatic compounds, such as 1-Bromo-3-chloropropane, are moderately or very reactive. Reactivity generally decreases with increased degree of substitution of halogen for hydrogen atoms. Materials in this group are incompatible with strong oxidizing and reducing agents. Also, they are incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.
Health Hazard	Inhalation of vapors or dust is extremely irritating. May cause burning of eyes and flow of tears. May cause coughing, difficult breathing and nausea. Brief exposure effects last only a few minutes. Exposure in an enclosed area may be very harmful. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may cause pollution.
Fire Hazard	Some of these materials may burn, but none ignite readily. Containers may explode when heated.
Safety Profile	Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of Cland Br-. See also CHLORINATED HYDROCARBONS, ALIPHATIC; and BROMIDES.
Purification Methods	Wash it with conc H2SO4, water, 10% Na2CO3 solution, water again and then dry with CaCl2 and fractionally distil it just before use [Akagi et al. J Am Chem Soc 78 4034 1956]. [Beilstein 1 H 109, 1 IV 212.]
Toxics Screening Level	The initial threshold screening level (ITSL) for 1-Bromo-3-chloropropane is 0.1 μg/m3 based on an annual averaging time.

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Basic Info

Product Name:

2-Chloroethyl acetate

Other Name:

Ethanol,2-chloro-,1-acetate;Ethanol,2-chloro-,acetate;2-Chloroethyl acetate;β-Chloroethyl acetate;2-Acetoxy-1-chloroethane;2-Acetoxyethyl chloride;1-Acetoxy-2-chloroethane;Acetic acid 2-chloroethyl ester;2-Chloroethanol acetate;NSC 77374

CAS No.:

542-58-5

Molecular Formula:

C4H7ClO2

InChIKeys:

InChIKey=VIRWKAJWTKAIMA-UHFFFAOYSA-N

Molecular Weight:

122.55

Exact Mass:

122.55

EC Number:

208-820-2

UNII:

8D17ZAW6MQ

NSC Number:

77374

HScode:

2915390090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

26.30000

XLogP3:

0.78830

Density:

1.178 g/cm³

Boiling Point:

145 °C

Flash Point:

54°C

Refractive Index:

1.411

Toxicity:

Oral-Rat LD50: 10 mg/kg; Oral-Mouse LD50: 250 mg/kg

Flammability characteristics:

Flammable; decomposes toxic chloride gas in fire

See More 2-Chloroethyl acetate Properties 

Hazard Identification

Classification of the substance or mixture

Flammable liquids, Category 3

Acute toxicity - Category 2, Oral

Acute toxicity - Category 2, Dermal

Acute toxicity - Category 2, Inhalation

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H226 Flammable liquid and vapour H300+H310+H330 Fatal if swallowed, in contact with skin or if inhaled
Prevention	P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P233 Keep container tightly closed. P240 Ground and bond container and receiving equipment. P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment. P242 Use non-sparking tools. P243 Take action to prevent static discharges. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P262 Do not get in eyes, on skin, or on clothing. P260 Do not breathe dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P284 [In case of inadequate ventilation] wear respiratory protection.
Response	P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse affected areas with water [or shower]. P370+P378 In case of fire: Use ... to extinguish. P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P316 Get emergency medical help immediately. P361+P364 Take off immediately all contaminated clothing and wash it before reuse. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P320 Specific treatment is urgent (see ... on this label).
Storage	P403+P235 Store in a well-ventilated place. Keep cool. P405 Store locked up. P403+P233 Store in a well-ventilated place. Keep container tightly closed.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 2-Chloroethyl acetate Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10 days

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

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Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221
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Product Name	Grade / Content	Price	Supplier Name	Details
ACETIC ACID 2-CHLOROETHYL ESTER 542-58-5	Pharmaceutical Grade/99		Hangzhou Zentra Bio-Chemical Co., Ltd.	Inquiry

Acetic acid 2-chloroethyl ester542-58-5

Product Details

Seller Information

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

More Choices Find All Products for Sale 

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