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Disodium fluorophosphate

Disodium fluorophosphate structure

Disodium fluorophosphate 

structure
  • CAS No:

    7631-97-2

  • Formula:

    FNa2O3P

  • Chemical Name:

    Disodium fluorophosphate

  • Synonyms:

    SODIUM FLUOROPHOSPHATE;Phosphorofluoridicacid,sodiumsalt;disodium fluoro-dioxido-oxophosphorane;DISODIUM FLUOROPHOSPHATE;fluorophosphoric acid, sodium salt;Sodium monofluorophosphate 94%;Sodiummonofluorophosphate94%;Fluoridophosphoric acid/sodium,(1:x) salt

  • Categories:

    Cosmetic Ingredient  >  Antiplaque

Description

Colorless crystals. Sol- uble in water.


Sodium fluorophosphate is sodium fluorophosphate, commonly abbreviated MFP, is an inorganic compound with the chemical formula Na2PO3F. Typical for a salt, MFP is odourless, colourless, and water-soluble. This salt is an ingredient in toothpastes. It has a role as an antibacterial agent. It is an inorganic sodium salt and an inorganic phosphate.|Sodium monofluorophosphate is used in OTC dental preparations to help protect against cavities.

Disodium fluorophosphate Basic Attributes

143.95

143.93600

231-552-2

C810JCZ56Q

TSCA listed

DTXSID70872554|DTXSID40872566

White

A - Alimentary tract and metabolism

2835299000

Characteristics

63.2

0.92500

White powder

625°C

-20°C Freezer

Safety Information

3

Xn,Xi

TE6130000

Xn,Xi

Irritant

P264, P270, P280, P301+P312, P302+P352, P321, P330, P332+P313, P362, P501

Toxic by ingestion, strong irritant.

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 8 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H302 (92.75%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P280, P301+P312, P302+P352, P321, P330, P332+P313, P362, and P501|Aggregated GHS information provided by 70 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Toxicity

LD50 Oral: rat-502 -638 mg/kg LC50 Inhalation: rat-male and female-4 h-> 2,1 mg/l

Drug Information

Sodium monofluorophosphate is indicated for the treatment of cavities

Substances that inhibit or arrest DENTAL CARIES formation. (Boucher's Clinical Dental Terminology, 4th ed) (See all compounds classified as Cariostatic Agents.)

ammonium monofluorophosphate

Disodium fluorophosphate Use and Manufacturing

Uses

It can be used as an anti-caries agent and tooth desensitizer in toothpaste formula instead of sodium fluoride. It can also be used to clean metal surfaces and as a flux. It can also be used to manufacture special glass


Preparation of bactericides and fungicides.

Phosphorofluoridic acid, sodium salt (1:?): ACTIVE

Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients|Cosmetics -> Antiplaque; Oral care

Computed Properties

Molecular Weight:143.950
Hydrogen Bond Acceptor Count:4
Exact Mass:143.93644758
Monoisotopic Mass:143.93644758
Topological Polar Surface Area:63.2
Heavy Atom Count:7
Complexity:49.8
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes

Drug Function and Efficacy

Prevents tooth decay by strengthening tooth enamel and inhibiting the growth of bacteria that cause cavities

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

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