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Home > Encyclopedia > ethyl2-methylquinoline-6-carboxylate

ethyl2-methylquinoline-6-carboxylate

ethyl2-methylquinoline-6-carboxylate structure

ethyl2-methylquinoline-6-carboxylate 

structure
  • CAS No:

    855763-77-8

  • Formula:

    C13H13NO2

  • Chemical Name:

    ethyl2-methylquinoline-6-carboxylate

  • Synonyms:

    ethyl2-methylquinoline-6-carboxylate;ethyl4-hydroxy-2-methylquinoline-6-carboxylate;2-Methylquinoline-6-carboxylic acid ethyl ester;2-Methyl-6-quinolinecarboxylic acid ethyl ester

  • Categories:

    Pharmaceutical Intermediates  >  Heterocyclic Compound

ethyl2-methylquinoline-6-carboxylate Basic Attributes

215.25

215.094635

DTXSID30652410

2933499090

Characteristics

39.2

3

Solid

1.1±0.1 g/cm3

334.4°C at 760 mmHg

156.1±22.3 °C

1.592

ethyl2-methylquinoline-6-carboxylate Use and Manufacturing

Accurately weigh 0.005mmol (l. Lmg) of the transition metal, add 10mL has been put into the magnetic stirrer Young's reaction tube, The oxygen reaction was carried out in the Young's reaction tube, and the reaction was carried out under oxygen conditions. The syringe was applied to the Young's reaction tubeAdd 0.04 mmol of co-catalyst I, 0.08 mmol of co-catalyst II, 0.2 mmol of ethyl 4-aminobenzoate and lmlWater, the Young's reaction tube was placed on a magnetic stirrer and stirred at 150 ° C for 36 hours. After completion of the reaction, the reaction solutionThe pH was neutral, and the reaction solution was post-treated to give pure 2-methyl-6-quinolinecarboxylic acid ethyl ester in 65percent yield.

Computed Properties

Molecular Weight:215.25
XLogP3:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:215.094628657
Monoisotopic Mass:215.094628657
Topological Polar Surface Area:39.2
Heavy Atom Count:16
Complexity:254
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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