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Felodipine

Felodipine structure

CAS No:
86189-69-7
Formula:
C18H19Cl2NO4
Chemical Name:
Felodipine
Synonyms:
4-(2,3-DICHLOROPHENYL)-1,4-DIHYDRO-2,6-DIMETHYL-3,5-PYRIDINECARBOXYLIC ACID METHYL ESTER;4-(2,3-DICHLOROPHENYL)-1,4-DIHYDRO-2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLIC ACID METHYL ESTER;FLODIL;FELODAY;ethyl methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate;Agon sr;Brn 4331472;Felodipina
Categories:
Active Pharmaceutical Ingredients > Circulatory System Drugs

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Description

Solid

Felodipine Basic Attributes

Molecular Weight：

384.25

Exact Mass：

384.25

Color/Form：

light yellow

Characteristics

PSA：

64.6

XLogP3：

3.8

Appearance：

light yellow solid

Density：

1.3±0.1 g/cm3

Melting Point：

145 °C

Boiling Point：

471.5±45.0 °C at 760 mmHg

Flash Point：

239.0±28.7 °C

Refractive Index：

1.550

Water Solubility：

DMSO: 28 mg/mL

Safety Information

wgk germany：

hazard class code：

RTECS Number：

US7968700

Marks：

Precautionary statement(s)：

P201, P202, P260, P264, P270, P273, P281, P301+P312, P308+P313, P314, P330, P391, P405, P501

Hazard Statements：

Felodipine Use and Manufacturing

Used to treat hypertension, ischemic heart disease, heart failure and other diseases

Vasodilator.

Drug Function and Efficacy

Extract from the above information

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Felodipine

Felodipine Tablets
Ingredients	The main ingredient of this product is felodipine. Its chemical name is 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3-pyridinedicarboxylic acid ethyl ester methyl ester.
Indication	1 When taking this product, taking drugs that affect cytochrome P450 at the same time may affect the blood concentration of felodipine. 2 Enzyme inducing drugs (such as phenytoin, carbamazepine, barbiturates) can cause a decrease in the blood concentration of felodipine. 3 Enzyme inhibitors (cimetidine) can cause an increase in the blood concentration of felodipine. Although felodipine has a high degree of plasma protein binding, it does not affect the binding degree of other plasma protein binding drugs (such as warfarin).
Specifications	5mg
Manufacturer	Beijing Sihuan Pharmaceutical Co., Ltd.

Felodipine Tablets
Ingredients	The main ingredient of this product is felodipine, and its chemical name is 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3-pyridinedicarboxylic acid ethyl ester methyl ester.
Indication	1. When taking this product, taking drugs that affect cytochrome P450 at the same time may affect the blood concentration of felodipine. 2. Enzyme inducing drugs (such as phenytoin, carbamazepine, barbiturates) can cause a decrease in the blood concentration of felodipine. 3. Enzyme inhibitors (cimetidine) can cause an increase in the blood concentration of felodipine. Although felodipine has a high degree of plasma protein binding, it does not affect the binding degree of other plasma protein binding drugs (such as warfarin).
Specifications	5 mg
Manufacturer	Beijing Xiehe Pharmaceutical Co., Ltd.

See More Related Drugs

Registered Holders

EVERLIGHT CHEMICAL INDUSTRIAL CORP

United States
Active
APITORIA PHARMA PRIVATE LTD

United States
Active
MEDICHEM SA

Spain
Active

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