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Brovincamine

Brovincamine structure

CAS No:
57475-17-9
Formula:
C21H25BrN2O3
Chemical Name:
Brovincamine
Synonyms:
Eburnamenine-14-carboxylic acid,11-bromo-14,15-dihydro-14-hydroxy-,methyl ester,(3α,14β,16α)-;1H-Indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine,eburnamenine-14-carboxylic acid deriv.;(+)-cis-11-Bromovincamine;cis-11-Bromovincamine;11-Bromovincamine;Brovincamine;11-Brovincamine
Categories:
Active Pharmaceutical Ingredients > Nervous System Drugs

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Description

Brovincamine is an alkaloid.

Brovincamine Basic Attributes

Molecular Weight：

433.344

Exact Mass：

433.34

UNII：

AYN5T18K5R

Characteristics

PSA：

54.7

XLogP3：

3.65290

Density：

1.59g/cm3

Melting Point：

214 °C (decomp)

Boiling Point：

547.9ºC at 760mmHg

Flash Point：

285.2ºC

Refractive Index：

1.705

Specific rotation：

D20 +8.7° (1% in CHCl3)

Drug Information

MeSH：

Drugs used to cause dilation of the blood vessels. (See all compounds classified as Vasodilator Agents.)

MeSH Entry Terms：

11-bromovincamine

Brovincamine Use and Manufacturing

It has the effect of accelerating the blood flow of the vertebral artery, internal carotid artery and cerebral, and the vasodilatory effect caused by calcium antagonism. It is an agent for improving cerebral circulation and metabolism. It is used to improve various symptoms of cerebral infarction sequelae and cerebral arteriosclerosis.

Computed Properties

Molecular Weight:433.3
XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:432.10486
Monoisotopic Mass:432.10486
Topological Polar Surface Area:54.7
Heavy Atom Count:27
Complexity:633
Defined Atom Stereocenter Count:3
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes