Boronic acid, B-[4-(1-phenyl-1H-benzimidazol-2-yl)phenyl]-
-
![Boronic acid, B-[4-(1-phenyl-1H-benzimidazol-2-yl)phenyl]- structure](https://file.echemi.com/fileManage/upload/canonicalSmiles/20220811/d5459c32ef0d4c7e8d00220e51f6d16f.png "Boronic acid, B-[4-(1-phenyl-1H-benzimidazol-2-yl)phenyl]-")
Boronic acid, B-[4-(1-phenyl-1H-benzimidazol-2-yl)phenyl]-
structure -
-
CAS No:
952514-79-3
-
Formula:
C19H15BN2O2
-
Chemical Name:
Boronic acid, B-[4-(1-phenyl-1H-benzimidazol-2-yl)phenyl]-
-
Synonyms:
Boronic acid, B-[4-(1-phenyl-1H-benzimidazol-2-yl)phenyl]-;4-(1-Phenyl-1H-benzimidazol-2-yl)phenylboronic acid;B-[4-(1-Phenyl-1H-benzimidazol-2-yl)phenyl]boronic acid;B(OH)2 4-(1-Phenyl-1H-benziMidazol -2-yl)phenylboronic acid;[3-(1-phenyl-1H-benziMidazol-2-yl)phenyl]Boronic acid;4-(1-phenyl-1H-benzo[d]iMidazol-2-yl)phenylboronic acid(PBIB);BIBA;1-phenyl-2-( phenyl-4-boromic acid)-benzimidazole
- Categories:
-
CAS No:
Boronic acid, B-[4-(1-phenyl-1H-benzimidazol-2-yl)phenyl]- Basic Attributes
314.15
314.122650
DTXSID80693030
2933990090
Safety Information
P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, P362
H315
|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, and P362|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Boronic acid, B-[4-(1-phenyl-1H-benzimidazol-2-yl)phenyl]- Use and Manufacturing
Synthesis of Compound 15-5 The 7g2 - (4-bromophenyl) - 1-phenyl-benzimidazole (0.02mole) adding 150mlTHF in, lower the temperature to -78 °C, at -78 ° C dropping under 12 ml (2.5M/L, 0 . 03mole) n-BuLi, thermal insulation 30 minutes, dropping 4.26g (0.041mole) methyl borate, reaction 2 hours after the reaction end of the, water in the reaction solution of 50 ml, stirring 20 minutes, hydrochloric acid to adjust pH value to acidity, stirring 30 minutes, the reaction solution with ethyl acetate extraction three times, washing time combined with the organic layer, the organic phase is separated, turns on lathe does, solid with petroleum ether heat two times, filtering, to obtain solid intermediates kind of white G9-1, yield 65percent.Under nitrogen, the compound 17-1 (10.6g, 29mmol) and dried tetrahydrofuran (100mL) added to the three-necked flask was cooled to -78 .Followed by stirring slowly with a syringe injection 2.5 moles per liter of n-BuLi hexane solution (20mL, 50mmol), and then added triisopropyl borate (8.1g, 43mmol), stirring was continued at this temperature for 1 hour and then It was slowly warmed to room temperature and stirred overnight under nitrogen.After the reaction, the reaction mixture was poured into dilute hydrochloric acid solution in 2N, extracted three times with ethyl acetate, the combined organic phase was washed with water and brine, dried over anhydrous sodium sulfate.The solvent was removed to give the crude product was recrystallized from ethyl acetate and n-hexane 8.3g of white solid with a yield of 74percent.
Computed Properties
Molecular Weight:314.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:314.1226579
Monoisotopic Mass:314.1226579
Topological Polar Surface Area:58.3
Heavy Atom Count:24
Complexity:408
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of Boronic acid, B-[4-(1-phenyl-1H-benzimidazol-2-yl)phenyl]-
-
![China]()
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives -
![China]()
CN
5 YRS
Business licensed Certified factoryManufactory Supplier of Active Pharm Ingredients,Chemical Catalyst,Pharmaceutical Intermediates,Flavors and Fragrances,Agrochemicals,Chemical Pesticides,Organic Intermediates,OLED IntermediatesInquiryCAS No.: 952514-79-3Grade: Industrial GradeContent: 99% -
![China]()
CN
5 YRS
Business licensedTrader Supplier of PVC resin,pvc paste resin,melamineInquiryCAS No.: 952514-79-3Grade: Industrial GradeContent: 99%
Learn More Other Chemicals
-
1-Cyclohexene-1-carboxylic acid, 4-(1-hydroxyethyl)- (9CI)
42569-41-5
-
Cyclohexanecarboxylic acid, 1,3,4,5-tetrahydroxy-, ethyl ester, (1alpha,3R,4alpha,5R)- (9CI)
463325-95-3
-
Cyclopentaneacetic acid, 3-amino-3-carboxy-, trans- (9CI)
194785-81-4
-
Cyclobutanecarboxylic acid, 2,3-bis(hydroxymethyl)- (9CI) Formula
150521-41-8
-
Cyclopentanecarboxylic acid, 2-hydroxy-, hydrazide, trans- (9CI) Formula
130023-72-2
-
1-Cyclopentene-1-carboxylic acid, 3,3,5-trimethyl- (9CI) Formula
56850-60-3
-
Cyclobutanecarboxylic acid, 1-(formylamino)- (9CI) Structure
777803-50-6
-
2-Cyclobutene-1-carboxylic acid, 4-(chlorocarbonyl)-, methyl ester, cis- (9CI) Structure
139591-41-6
-
What is Cyclopropanecarboxylic acid, 1-formyl-2-methyl-, ethyl ester (9CI)
260261-27-6
-
What is Cyclohexanecarboxylic acid, 1-amino-2-hydroxy-, (1S,2R)- (9CI)
226905-10-8
Boronic acid, B-[4-(1-phenyl-1H-benzimidazol-2-yl)phenyl]-
SDSRequest for Quotation