4,6-DICHLORO-5-FLUORO-2-METHYLPYRIMIDINE
-
4,6-DICHLORO-5-FLUORO-2-METHYLPYRIMIDINE
structure -
-
CAS No:
105806-13-1
-
Formula:
C5H3Cl2FN2
-
Chemical Name:
4,6-DICHLORO-5-FLUORO-2-METHYLPYRIMIDINE
-
Synonyms:
4,6-Dichloro-5-fluoro-2-methylpyrimidine;Pyrimidine, 4,6-dichloro-5-fluoro-2-methyl-;2-methyl-4,6-dichloro-5-fluoropyrimidine;ACMC-209ype;C5H3Cl2FN2;4,6-DICHLORO-5-FLUORO-2-METHYL-PYRIMIDINE;SCHEMBL116963;CTK0H0446;DTXSID80547842;BCP23310
- Categories:
-
CAS No:
4,6-DICHLORO-5-FLUORO-2-METHYLPYRIMIDINE Use and Manufacturing
Part B: 4, 6-Dichloro-5-fluoro-2-methylpyrimidine. 5-Fluoro-4, 6-dihydroxy-2-methylpyrimidine (assumed 60 g, 0.42 mol) was treated with 300 ml. of POCI3 at 120 Part B: 4, 6-Dichloro-5-fluoro-2-methylpyrimidine 5-Fluoro-4, 6-dihydroxy-2-methylpyrimidine (assumed 60 g, 0.42 mol) was treated with 300 mL of POCIPart B: A mixture of 4, 6-dihydroxy-5-fluoro-2-methylpyrimidine (2.00 g, 13.9 mmol), phosphorous oxychloride (15.0 mL, 161 mmol), and JV, iV-diinethyIaniline (2.00 mL, 15.8 mmol) was heated at reflux for 2 h. The reaction mixture was cooled to RT and concentrated under reduced press. The residue was poured onto ice and allowed to warm to RT as a ppt formed. The solids were collected by suction filtration, washed with water, and air-dried at RT for Ih to give 4, 6-dichloro-5-fluoro-2-methylpyrimidine (1.56 g, 62percent) as a tan solid. LCMS (m/z): 181, 183 (M+H)Part B:
Computed Properties
Molecular Weight:180.99
XLogP3:2.6
Hydrogen Bond Acceptor Count:3
Exact Mass:179.9657317
Monoisotopic Mass:179.9657317
Topological Polar Surface Area:25.8
Heavy Atom Count:10
Complexity:112
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of 4,6-DICHLORO-5-FLUORO-2-METHYLPYRIMIDINE
-
![China]()
CN
3 YRS
Business licensed Certified factoryManufactory Supplier of 4-(Pentafluorothio)aniline,Pentafluoro,Pentafluorothio,Pentafluorosulfur,[4-(bromomethyl)phenyl]-pentafluoro-lambda6-sulfane,[4-(pentafluoro-sulfanyl)phenyl]acetic acidInquiryCAS No.: 105806-13-1Grade: Industrial GradeContent: 95%
Learn More Other Chemicals
-
(2E)-3-(1-METHYL-1H-PYRROL-2-YL)ACRYLIC ACID
51485-76-8
-
Benadryl N-oxide hydrochloride
13168-00-8
-
6-CHLORO-3-IODO-IMIDAZO[1,2-A]PYRIDINE
885275-59-2
-
(2-Bromophenyl)diphenylphosphine Formula
62336-24-7
-
1-Morpholinocyclopentene Formula
936-52-7
-
4-[2-(Boc-amino)ethoxy]-benzoic acid Formula
168892-66-8
-
3-amino-5-bromopyridine-2-carboxylic acid Structure
870997-85-6
-
2-Amino-6-methylpyridine Structure
1824-81-3
-
What is 3-Bromo-2-methylthiophene
30319-05-2
-
What is THIOPHEN-2-YLMETHYL-PHOSPHONICACIDDIETHYLESTER
2026-42-8
4,6-DICHLORO-5-FLUORO-2-METHYLPYRIMIDINE
SDSRequest for Quotation