2-Bromopyridine-4-methanol
-
2-Bromopyridine-4-methanol
structure -
-
CAS No:
118289-16-0
-
Formula:
C6H6BrNO
-
Chemical Name:
2-Bromopyridine-4-methanol
-
Synonyms:
2-BROMO-4-(HYDROXYMETHYL)PYRIDINE;2-BROMO-4-PYRIDINE METHANOL;(2-BROMO-PYRIDIN-4-YL)-METHANOL;2-BROMOPYRIDINE-4-METHANOL;RARECHEM AL BD 1524;2-Bromopyridine-4-methanol ,96%;Bromopyridine-4-Methanol;4-Pyridinemethanol, 2-bromo-
- Categories:
-
CAS No:
Characteristics
33.1
1
1.668±0.06 g/cm3(Predicted)
58-61°C
316.6±27.0 °C(Predicted)
145.3±23.7 °C
1.599
Safety Information
IRRITANT
NONH for all modes of transport
1
36/37/38-22
26-36-37-22
Xi,Xn
P261-P280-P305 + P351 + P338
H302-H315-H318-H335
|Danger|H302 (90.7%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P330, P332+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 43 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
2-Bromopyridine-4-methanol Use and Manufacturing
To a solution of 215.1 (2g, 9.9mmol, l .Oeq) in tetrahydrofuran (30mL) at 0°C, boron trifluoride etherate (4.18g, 29.7mmol, 3.0eq) was added dropwise. Reaction mixture was stirred at room temperature for 3h. After completion of reaction, reaction mixture was transferred in ice-water and product was extracted with ethyl acetate. Organic layer was combined, washed with brine solution, dried over sodium sulphate and concentrated under reduced pressure to obtain 1.1 (1.4g, 75.21percent). MS(ES): m/z 189.65 [M]To a solution of 2-bromopyridine-4-carbaldehyde (20 g, 107.52 mmol) in MeOH (150 mL) was added portion wise sodium borohydride (12.0 g, 322.56 mmol) at 0° C. under inert atmosphere.
Computed Properties
Molecular Weight:188.02
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:186.96328
Monoisotopic Mass:186.96328
Topological Polar Surface Area:33.1
Heavy Atom Count:9
Complexity:89.1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of 2-Bromopyridine-4-methanol
-
![China]()
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives -
![China]()
CN
4 YRS
Business licensedTrader Supplier of Fluorine containing fine chemicals Pharmaceutical -
![China]()
CN
3 YRS
Business licensed Certified factoryManufactory Supplier of Dyes,Textile agent,Medical intermediate,API,Pigments,Basic Chemicals
Learn More Other Chemicals
-
(2E)-3-(1-METHYL-1H-PYRROL-2-YL)ACRYLIC ACID
51485-76-8
-
Benadryl N-oxide hydrochloride
13168-00-8
-
6-CHLORO-3-IODO-IMIDAZO[1,2-A]PYRIDINE
885275-59-2
-
(2-Bromophenyl)diphenylphosphine Formula
62336-24-7
-
1-Morpholinocyclopentene Formula
936-52-7
-
4-[2-(Boc-amino)ethoxy]-benzoic acid Formula
168892-66-8
-
3-amino-5-bromopyridine-2-carboxylic acid Structure
870997-85-6
-
2-Amino-6-methylpyridine Structure
1824-81-3
-
What is 3-Bromo-2-methylthiophene
30319-05-2
-
What is THIOPHEN-2-YLMETHYL-PHOSPHONICACIDDIETHYLESTER
2026-42-8