 Home > Encyclopedia > 7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE, 1,4-DIHYDRO-

7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE, 1,4-DIHYDRO-

7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE, 1,4-DIHYDRO- structure

CAS No:
13877-55-9
Formula:
C5H4N4O
Chemical Name:
7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE, 1,4-DIHYDRO-
Synonyms:
7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE, 1,4-DIHYDRO-;7H-Pyrazolo[4,3-d]pyrimidin-7-one, 1,4-dihydro- (9CI);7-ketopyrazolo(4,3-d)pyrimidine;7H-Pyrazolo[4,3-d]pyrimidin-7-one;1,4-Dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one;7-Hydroxypyrazolo[4,3-d]pyrimidine;1H-Pyrazolo(4,3-D)pyrimidin-7-ol (8ci);1H-Pyrazolo(4,3-D)pyrimidine-7-one
Categories:
Pharmaceutical Intermediates > Heterocyclic Compound

Request for Quotation

7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE, 1,4-DIHYDRO- Basic Attributes

Molecular Weight：

136.11

Exact Mass：

136.038513

UNII：

L69P3N2EVQ

NSC Number：

79301

DSSTox ID：

DTXSID60160775

HScode：

2933990090

Characteristics

PSA：

70.1

XLogP3：

-0.7

Density：

1.89±0.1 g/cm3(Predicted)

Melting Point：

>30 °C(Solv: water (7732-18-5))

Boiling Point：

559.8±23.0 °C(Predicted)

Flash Point：

292.3±22.6 °C

Refractive Index：

1.903

Safety Information

GHS Classification：

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Drug Information

MeSH Entry Terms：

1H-pyrazolo(4,3-d)pyrimidine-7-one

7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE, 1,4-DIHYDRO- Use and Manufacturing

Compound 27: Formamidine acetate (40.3 mmol, 4.2 g) was added to a solution containing 26 (8.85 g, 36.7 mmol) in Hunig's base (40 mL) and n-BuOH (40 mL). The stirred solution was heated at 110° C. for 1 hour. After cooling to ambient temperature the resulting solid was collected, washed with dichloromethane, and dried under reduced pressure to afford 27 (4.46 g, 89percent), ES (+) MS m/e=137.Compound 28: DMF (1.05 mL) was added to a solution containing 27 (1.0 g, 7.3 mmol) in thionyl chloride (21 mL). Heated the stirring solution to 90 C. for 1 hour. Cooled the homogeneous reaction mixture to room temperature. Concentrated to remove volatiles and diluted the reaction mixture with EtOAc followed by ice. Extracted the aqueous layer with EtOAc. Combined the organics, washed with saturated NaHCO3, dried with MgSO4, filtered and concentrated to afford 28 (0.73 g, 64%), ES (+) MS m/e=155.[0507] Procedure: To a stirred solution of Compound 27: Formamidine acetate (40.3 mmol, 4.2 g) was added to a solution containing 26 (8.85 g, 36.7 mmol) in Hunig's base (40 mL) and n-BuOH (40 mL). The stirred solution was heated at 110 C. for 1 hour. After cooling to ambient temperature the resulting solid was collected, washed with dichloromethane, and dried under reduced pressure to afford 27 (4.46 g, 89%), ES (+) MS m/e=137.

Computed Properties

Molecular Weight:136.11
XLogP3:-0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Exact Mass:136.03851076
Monoisotopic Mass:136.03851076
Topological Polar Surface Area:70.1
Heavy Atom Count:10
Complexity:190
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of 7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE, 1,4-DIHYDRO-

Compound Net Biotechnology Inc. Contact Supplier

CN
2 YRS

Business licensed Certified factory

Manufactory Supplier of 4-(Pentafluorothio)aniline,Pentafluoro,Pentafluorothio,Pentafluorosulfur,[4-(bromomethyl)phenyl]-pentafluoro-lambda6-sulfane,[4-(pentafluoro-sulfanyl)phenyl]acetic acid

13877-55-9 1,6-dihydropyrazolo[4,3-d]pyrimidin-7-one

CAS No.: 13877-55-9

Grade: Industrial Grade

Content: 95%

Inquiry

Latest News on 7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE, 1,4-DIHYDRO-

Learn More Other Chemicals

Dibenzofuran, 1,4-dihydro-

103264-74-0
(2E)-3-(1-METHYL-1H-PYRROL-2-YL)ACRYLIC ACID

51485-76-8
Benadryl N-oxide hydrochloride

13168-00-8
6-CHLORO-3-IODO-IMIDAZO[1,2-A]PYRIDINE Formula

885275-59-2
(2-Bromophenyl)diphenylphosphine Formula

62336-24-7
1-Morpholinocyclopentene Formula

936-52-7
4-[2-(Boc-amino)ethoxy]-benzoic acid Structure

168892-66-8
3-amino-5-bromopyridine-2-carboxylic acid Structure

870997-85-6
What is 2-Amino-6-methylpyridine

1824-81-3
What is 3-Bromo-2-methylthiophene

30319-05-2

Hot Searches: polypropylene glycol; aloh3; phenylacetaldehyde; fluoroethylene carbonate; iodoform; 1 3 bisphosphoglycerate

Guide of 7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE, 1,4-DIHYDRO-

Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
Latest News
Learn More Other Chemicals

7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE, 1,4-DIHYDRO-

SDS

Request for Quotation



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.