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Home > Encyclopedia > 4-AMINO-2-ETHYLSULFANYL-PYRIMIDINE-5-CARBONITRILE

4-AMINO-2-ETHYLSULFANYL-PYRIMIDINE-5-CARBONITRILE

4-AMINO-2-ETHYLSULFANYL-PYRIMIDINE-5-CARBONITRILE structure

4-AMINO-2-ETHYLSULFANYL-PYRIMIDINE-5-CARBONITRILE 

structure
  • CAS No:

    16462-29-6

  • Formula:

    C7H8N4S

  • Chemical Name:

    4-AMINO-2-ETHYLSULFANYL-PYRIMIDINE-5-CARBONITRILE

  • Synonyms:

    4-AMINO-2-ETHYLSULFANYL-PYRIMIDINE-5-CARBONITRILE;4-Amino-2-(ethylthio)-5-pyrimidinecarbonitrile;5-Cyano-4-amino-2-ethylsulfanylpyrimidine;5-PyriMidinecarbonitrile,4-aMino-2-(ethylthio)-;4-amino-2-(ethylthio)pyrimidine-5-carbonitrile

  • Categories:

    Pharmaceutical Intermediates  >  Heterocyclic Compound

4-AMINO-2-ETHYLSULFANYL-PYRIMIDINE-5-CARBONITRILE Basic Attributes

180.23022

180.04700

2933599090

Characteristics

101

1.3

1.326 g/cm3

399.013°C at 760 mmHg

195.116ºC

1.621

0mmHg at 25°C

4-AMINO-2-ETHYLSULFANYL-PYRIMIDINE-5-CARBONITRILE Use and Manufacturing

A solution of 2-Ethyl-2-thiopsuedourea hydrobromide (1.52 g, 8.19 mmol), (Ethoxymethylene)malononitrile (1.0 g, 8.19 mmol) and N, N-diisopropylethylamine (3.57 mL, 20.05 mmol) in ethanol (20 mL) was stirred at room temperature for 3.5 hours. The resultant solid was collected, washed with ethanol, and the dried under vacuum to provide the title compound as a light yellow solid (580 mg, 39percent).4-Amino-5-cyano-2-ethylthiopyrimidine. A solution of 2-Ethyl-2-thiopsuedourea hydrobromide (1.52 g, 8.19 mmol), (Ethoxymethylene)malononitrile (1.0 g, 8.19 mmol) and N, N-diisopropylethylamine (3.57 mL, 20.05 mmol) in ethanol (20 mL) was stirred at room temperature for 3.5 hours. The resultant solid was collected, washed with ethanol, and the dried under vacuum to provide the title compound as a light yellow solid (580 mg, 39percent).4-Amino-5-cyano-2-ethylthiopyrimidine.

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