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Dinaciclib

Dinaciclib structure

CAS No:
779353-01-4
Formula:
C21H28N6O2
Chemical Name:
Dinaciclib
Synonyms:
2-Piperidineethanol,1-[3-ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-,(2S)-;(2S)-1-[3-Ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2-piperidineethanol;Dinaciclib;Sch 727965;2-[(2S)-1-[3-Ethyl-7-[(1-oxidopyridin-1-ium-3-yl)methylamino]pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-2-yl]ethanol;1000697-89-1
Categories:
Pharmaceutical Intermediates > Heterocyclic Compound

Description

Dinaciclib is a potent inhibitor of CDK, with IC50s of 1, 1, 3, and 4 nM for CDK2, CDK5, CDK1, and CDK9, respectively.

Molecular Weight：

396.48602

Exact Mass：

396.49

PSA：

91.2

XLogP3：

1.9

Density：

1.33

Refractive Index：

1.677

Precautionary statement(s)：

P201, P202, P260, P264, P270, P280, P281, P302+P352, P305+P351+P338, P308+P313, P314, P321, P332+P313, P337+P313, P362, P405, P501

Hazard Statements：

H315

Dinaciclib is a potent and selective inhibitor of cyclin-dependent kinases which is undergoing development as oncology therapeutics.

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HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

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(2S)-1-[3-Ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2-piperidineethanol

CAS No.: 779353-01-4

Content: 99.00%

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Creative Enzymes Contact Supplier

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Dinaciclib(SCH727965)

CAS No.: 779353-01-4

Content: 99%

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