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Home > Encyclopedia > Fenarimol

Fenarimol

Fenarimol structure

Fenarimol 

structure
  • CAS No:

    60168-88-9

  • Formula:

    C17H12Cl2N2O

  • Chemical Name:

    Fenarimol

  • Synonyms:

    5-Pyrimidinemethanol,α-(2-chlorophenyl)-α-(4-chlorophenyl)-;α-(2-Chlorophenyl)-α-(4-chlorophenyl)-5-pyrimidinemethanol;Fenarimol;EL 222;Rubigan;Fenari;Rubigan SC;(±)-Fenarimol;162707-16-6;1135442-57-7

  • Categories:

    Pharmaceutical Intermediates  >  Heterocyclic Compound

Description

Solid


Pure white crystalline solid. Used as a fungicide. Irritates skin and mucous membranes.|Solid


Pure white crystalline solid. Used as a fungicide. Irritates skin and mucous membranes.|(2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol is a member of the class of pyrimidines that is pyrimidin-5-ylmethanol in which one of the hydrogens attached to the carbon bearing the hydroxy group is replaced by a 2-chlorophenyl group while the other is replaced by a 4-chlorophenyl group. It is a tertiary alcohol, a member of monochlorobenzenes and a member of pyrimidines.

Fenarimol Basic Attributes

331.2

331.20

262-095-7

3017

DTXSID2032390

2933599090

Characteristics

46

3.22

Pure white crystalline solid. Used as a fungicide. Irritates skin and mucous membranes.

1.40 g/cm3

118 °C

0°C

0°C

1.643

14.6 mg l -1 (pH 3), 13.7 mg l -1 (pH 7), 13.8 mg l -1 (pH 10) at 25 °C

0-6°C

6.5 x 10 -5 Pa at 25 °C

Oral-Rat LD50: 2500 mg/kg; Oral-Mouse LD50: 4500 mg/kg

Combustion produces toxic nitrogen oxides and chloride gases

175.92 Ų [M-H]-

No rapid reaction with air. No rapid reaction with water.

Alcohols and Polyols

FENARIMOL produces toxic gases when heated to decomposition.

Safety Information

6.1

UN 3017/3077

2

51/53-62-63-64

36/37-61

UV9279400

Xn;N,N,Xn

The warehouse is ventilated, low temperature and dry; stored and transported separately from food materials

P263-P273-P281

H361-H362-H411

Excerpt from ERG Guide 131 [Flammable Liquids - Toxic]: HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion and poison hazard indoors, outdoors or in sewers. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water. (ERG, 2016)

|Warning|H361fd: Suspected of damaging fertility; Suspected of damaging the unborn child [Warning Reproductive toxicity]|P201, P202, P260, P263, P264, P270, P273, P281, P308+P313, P391, P405, and P501|H361 (99.09%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]|Aggregated GHS information provided by 330 companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H302: Harmful if swallowed [Warning Acute toxicity, oral]|P201, P202, P260, P264, P270, P281, P301+P312, P305+P351+P338, P308+P313, P309+P311, P314, P330, P337+P313, P405, and P501

Excerpt from ERG Guide 131 [Flammable Liquids - Toxic]: CAUTION: All these products have a very low flash point: Use of water spray when fighting fire may be inefficient. SMALL FIRE: Dry chemical, CO2, water spray or alcohol-resistant foam. LARGE FIRE: Water spray, fog or alcohol-resistant foam. Move containers from fire area if you can do it without risk. Dike fire-control water for later disposal; do not scatter the material. Use water spray or fog; do not use straight streams. FIRE INVOLVING TANKS OR CAR/TRAILER LOADS: Fight fire from maximum distance or use unmanned hose holders or monitor nozzles. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks engulfed in fire. For massive fire, use unmanned hose holders or monitor nozzles; if this is impossible, withdraw from area and let fire burn. (ERG, 2016)

Excerpt from ERG Guide 131 [Flammable Liquids - Toxic]: As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)

Excerpt from ERG Guide 131 [Flammable Liquids - Toxic]: Fully encapsulating, vapor-protective clothing should be worn for spills and leaks with no fire. ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). All equipment used when handling the product must be grounded. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. A vapor-suppressing foam may be used to reduce vapors. SMALL SPILL: Absorb with earth, sand or other non-combustible material and transfer to containers for later disposal. Use clean, non-sparking tools to collect absorbed material. LARGE SPILL: Dike far ahead of liquid spill for later disposal. Water spray may reduce vapor, but may not prevent ignition in closed spaces. (ERG, 2016)

Excerpt from ERG Guide 131 [Flammable Liquids - Toxic]: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible. (ERG, 2016)

Toxicity

moderately toxic

602.56 L/kg

Drug Information

Chemicals that kill or inhibit the growth of fungi in agricultural applications, on wood, plastics, or other materials, in swimming pools, etc. (See all compounds classified as Fungicides, Industrial.)

3.72 Days

Excerpt from ERG Guide 131 [Flammable Liquids - Toxic]: TOXIC; may be fatal if inhaled, ingested or absorbed through skin. Inhalation or contact with some of these materials will irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution. (ERG, 2016)

Excerpt from ERG Guide 131 [Flammable Liquids - Toxic]: Ensure that medical personnel are aware of the material(s) involved and take precautions to protect themselves. Move victim to fresh air. Call 911 or emergency medical service. Give artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult. Remove and isolate contaminated clothing and shoes. In case of contact with substance, immediately flush skin or eyes with running water for at least 20 minutes. Wash skin with soap and water. In case of burns, immediately cool affected skin for as long as possible with cold water. Do not remove clothing if adhering to skin. Keep victim calm and warm. Effects of exposure (inhalation, ingestion or skin contact) to substance may be delayed. (ERG, 2016)

alpha-(2-chlorophenyl)-alpha-(4-chlorophenyl)-5-pyrimidinemethanol

Fenarimol Use and Manufacturing

Uses

Plant fungicide.

5-Pyrimidinemethanol, .alpha.-(2-chlorophenyl)-.alpha.-(4-chlorophenyl)-: ACTIVE

Agrochemicals -> Fungicides|Fungicides

Computed Properties

Molecular Weight:331.2
XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:330.0326684
Monoisotopic Mass:330.0326684
Topological Polar Surface Area:46
Heavy Atom Count:22
Complexity:357
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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