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Home > Encyclopedia > 2,4-Imidazolidinedione, 1-[[[5-(4-nitrophenyl)-2-furanyl]methylene]amino]-, sodium salt, hydrate (2:2:7)

2,4-Imidazolidinedione, 1-[[[5-(4-nitrophenyl)-2-furanyl]methylene]amino]-, sodium salt, hydrate (2:2:7)

pharmaceutical raw materials
2,4-Imidazolidinedione, 1-[[[5-(4-nitrophenyl)-2-furanyl]methylene]amino]-, sodium salt, hydrate (2:2:7) structure

2,4-Imidazolidinedione, 1-[[[5-(4-nitrophenyl)-2-furanyl]methylene]amino]-, sodium salt, hydrate (2:2:7) 

structure
  • CAS No:

    24868-20-0

  • Formula:

    C14H10N4O5.7/2H2O.Na

  • Chemical Name:

    2,4-Imidazolidinedione, 1-[[[5-(4-nitrophenyl)-2-furanyl]methylene]amino]-, sodium salt, hydrate (2:2:7)

  • Synonyms:

    2,4-Imidazolidinedione,1-[[[5-(4-nitrophenyl)-2-furanyl]methylene]amino]-,sodium salt,hydrate (2:2:7);Hydantoin,1-[[5-(p-nitrophenyl)furfurylidene]amino]-,sodium salt,hydrate (2:7);2,4-Imidazolidinedione,1-[[[5-(4-nitrophenyl)-2-furanyl]methylene]amino]-,sodium salt,hydrate (2:7);1-[[5-(p-Nitrophenyl)furfurylidene]amino]hydantoin sodium salt hydrate

  • Categories:

    Active Pharmaceutical Ingredients  >  Anesthetic Agents

Description

Dantrolene sodium hemiheptahydrate is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction. Dantrolene sodium hemiheptahydrate is a inhibitor of calcium channel proteins, inhibiting the release of Ca2+ from the sarcoplasm.

2,4-Imidazolidinedione, 1-[[[5-(4-nitrophenyl)-2-furanyl]methylene]amino]-, sodium salt, hydrate (2:2:7) Basic Attributes

336.23

336.047064

238-706-8

2934999090

Characteristics

127

>230°C

544.5°C at 760 mmHg

283.1ºC

18.4 [ug/mL]

-20°C Freezer

Safety Information

NONH for all modes of transport

2

22-24/25

MU3875000

2,4-Imidazolidinedione, 1-[[[5-(4-nitrophenyl)-2-furanyl]methylene]amino]-, sodium salt, hydrate (2:2:7) Use and Manufacturing

A muscle relaxant (skeletal). Used in the treatment of malignant hyperthermia

Drug Function and Efficacy

Dantrolene sodium is a muscle relaxant that acts directly on skeletal muscle. Its main site of action is the sarcoplasmic reticulum of skeletal muscle, which weakens muscle contraction by inhibiting the release of calcium ions from the sarcoplasmic reticulum.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Registered Holders

  • BIOPHORE INDIA PHARMACEUTICALS PVT LTD

    United States United States
    Active
  • GLAND PHARMA LTD

    India India
    Active
  • SciAnda Shanghai Biochemical Technology, Ltd.

    China China
    Active

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