Metoprolol tartrate

684.82

684.383325

260-148-9

DTXSID9037248

29225090

216.50000

1.88560

white to off-white

1.1946 (rough estimate)

120-123 °C

398.6ºC at 760 mmHg

9℃

soluble in water (>1000 mg/ml), methanol (>500 mg/ml), chloroform (496 mg/ml), ethanol (31 mg/ml at 25°C), and DMSO (100 mg/ml at 25°C).

Desiccate at RT

Oral-Rat  LD50: 5500 mg/kg; Oral-Mouse LD50: 1500 mg/kg

Combustible; Fire site decomposes toxic nitrogen oxide gas

UN1230 - class 3 - PG 2 - Methanol, solution

3

11-23/24/25-39/23/24/25

7-16-36/37-45-24/25

UB7450100

F,T

Warehouse low temperature, ventilated, dry

Stable. Incompatible with strong oxidizing agents.

P210-P260-P280-P301 + P310-P311

H225-H301 + H311 + H331-H370

|Warning|H302 (11.39%): Harmful if swallowed [Warning Acute toxicity, oral]|P201, P202, P264, P270, P273, P280, P281, P301+P312, P302+P352, P305+P351+P338, P308+P313, P321, P330, P332+P313, P337+P313, P362, P405, and P501|Aggregated GHS information provided by 80 companies from 21 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

moderately toxic

Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade. (See all compounds classified as Anti-Arrhythmia Agents.)|Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. (See all compounds classified as Antihypertensive Agents.)|Drugs that bind to and block the activation of ADRENERGIC BETA-1 RECEPTORS. (See all compounds classified as Adrenergic beta-1 Receptor Antagonists.)|Drugs that inhibit the actions of the sympathetic nervous system by any mechanism. The most common of these are the ADRENERGIC ANTAGONISTS and drugs that deplete norepinephrine or reduce the release of transmitters from adrenergic postganglionic terminals (see ADRENERGIC AGENTS). Drugs that act in the central nervous system to reduce sympathetic activity (e.g., centrally acting alpha-2 adrenergic agonists, see ADRENERGIC ALPHA-AGONISTS) are included here. (See all compounds classified as Sympatholytics.)

Beloc Duriles

Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients