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EMETINE HCL

EMETINE HCL structure

CAS No:
14198-59-5
Formula:
C29H41ClN2O4
Chemical Name:
EMETINE HCL
Synonyms:
EMETINE HYDROCHLORIDE;EMETINE HCL;2H-Benzo[A]quinolizine, 3-ethyl-1,3,4,6,7,11B-hexahydro-9,10-dimethoxy-2-[(1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolyl)methyl]-, dihydrochloride;Cephaeline methyl ether HCl;Cephaeline methyl ether hydrochloride;Emetan, 6',7',10,11-tetramethoxy-, monohydrochloride;6',7',10,11-Tetramethoxyemetan monohydrochloride;EMetinal
Categories:
Active Pharmaceutical Ingredients > Antiparasitic Drugs

Description

Emetine hydrochloride, derived from the ipecac root, is a potent anti-protozoal and emetic agent. Emetine hydrochloride inhibits viral polymerases and inhibits Zika and Ebola virus infections. Emetine hydrochloride potently inhibits autophagy and has anti-malarial, anti-bacterial and anti-amoebic effect[1][2][3][4].

EMETINE HCL Basic Attributes

Molecular Weight：

517.1

Exact Mass：

516.275513

EC Number：

206-259-8

Characteristics

PSA：

52.19000

XLogP3：

6.01210

Density：

1.17g/cm3

Melting Point：

74 DEG C

Boiling Point：

624.8ºC at 760 mmHg

Flash Point：

331.7ºC

Water Solubility：

SPARINGLY SOL IN WATER, PETROLEUM ETHER, IN SOLN OF POTASSIUM OR SODIUM HYDROXIDE; FREELY SOL IN METHANOL, ETHYL ACETATE

Vapor Pressure：

4.54E-16mmHg at 25°C

Safety Information

Stability/Shelf Life：

Darkens on exposure to light.

Precautionary statement(s)：

P261, P264, P270, P271, P280, P301+P310, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, P501

Hazard Statements：

H300

EMETINE HCL Use and Manufacturing

Anti-amebic.