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Latamoxef sodium

Latamoxef sodium structure

CAS No:
64953-12-4
Formula:
C20H20N6O9S.2Na
Chemical Name:
Latamoxef sodium
Synonyms:
5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,sodium salt (1:2),(6R,7R)-;5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2R)-carboxy(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,disodium salt,(6R,7R)-;Shionogi 6059S;6059S;LY 127935;Moxalactam disodium;Latamoxef sodium;Disodium latamoxef;Shiomarin;Antibiotic 6059S;S 6059;LY 12735;Festamoxin;102696-28-6
Categories:
Active Pharmaceutical Ingredients > Antibiotics

Description

Moxalactam sodium salt is an antibiotic compound more effective against Escherichia coli and Pseudomonas aeruginosathan cephalosporins.

Latamoxef sodium Basic Attributes

Molecular Weight：

564.44

Exact Mass：

564.065125

EC Number：

265-288-4

DSSTox ID：

DTXSID0045595

Characteristics

PSA：

237 Å²

Storage Conditions：

2-8°C

Specific rotation：

D22 -45° (water)

Safety Information

Packing level：

Ⅲ

Transport codes：

2811

wgk germany：

hazard class code：

42/43

safety instructions：

22-36/37-45

RTECS Number：

RN6824000

Marks：

Precautionary statement(s)：

P261-P280-P342 + P311

Hazard Statements：

H317-H334

GHS Classification：

|Danger|H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]|P261, P272, P280, P285, P302+P352, P304+P341, P321, P333+P313, P342+P311, P363, and P501|Aggregated GHS information provided by 39 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Latamoxef sodium Use and Manufacturing

Antibacterial;Bacterialtranspeptidase inhibitor

Computed Properties

Molecular Weight:564.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:13
Rotatable Bond Count:7
Exact Mass:564.06513591
Monoisotopic Mass:564.06513591
Topological Polar Surface Area:237
Heavy Atom Count:38
Complexity:947
Undefined Atom Stereocenter Count:3
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes

Drug Function and Efficacy

Extract from the above information

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Latamoxef Sodium
Manufacturer	Hainan Xinhesai Pharmaceutical Co., Ltd.

Latamoxef Sodium for Injection
Ingredients	The main ingredient of this product is latamoxef sodium.
Indication	1. The combination of this product with anticoagulants such as heparin and drugs that affect platelet aggregation such as aspirin and diflunisal can increase bleeding tendency. 2. This product should not be used simultaneously with strong diuretics to avoid increasing renal toxicity.
Specifications	1.0g (calculated as C20H20N6O9S)
Manufacturer	Hainan Hailing Chemipharma Corporation Ltd.

Latamoxef Sodium for Injection
Ingredients	The main ingredient of this product is latamoxef sodium; its chemical name is (6R,7R)-7-[2-carboxy-2-(4-hydroxyphenyl)acetylamino]-7-methoxy-3-[(1-methyl-1H-tetrazolyl-5-yl)thiomethyl]-8-oxo-5-oxa-1-azabicyclo[4,2,0]oct-2-ene-2-carboxylic acid disodium salt. [Molecular formula] C20H18N6Na2O9S [Molecular weight] 564.45
Indication	(1) The combined use of this product with anticoagulants such as heparin and drugs that affect platelet aggregation such as aspirin and diflunisal may increase bleeding tendency. (2) This product should not be used simultaneously with strong diuretics to avoid increasing renal toxicity.
Specifications	Calculated as C20H20N6O9S, 0.25g
Manufacturer	Harbin Reputation Scale Pharmaceutical Co., Ltd.

See More Related Drugs

Registered Holders

Zhejiang Dongbang Pharmaceutical Co., Ltd.

China
Active
Shandong Ruiying Pioneer Pharmaceutical Co., Ltd.

China
Active
Hainan Xinhesai Pharmaceutical Co., Ltd.

China
Active

See More Registered Holders

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