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Tobramycin sulfate

Tobramycin sulfate structure

Tobramycin sulfate 

structure
  • CAS No:

    49842-07-1

  • Formula:

    C18H37N5O9.5/2H2O4S

  • Chemical Name:

    Tobramycin sulfate

  • Synonyms:

    D-Streptamine,O-3-amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribo-hexopyranosyl-(1→4)]-2-deoxy-,sulfate (2:5);D-Streptamine,O-3-amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribo-hexopyranosyl-(1→4)]-2-deoxy-,sulfate (2:5) (salt);Tobramycin sulfate;Nebcin;Tenemicin;Obracin;1-Epitobramycin sulfate;Gernebcin;Distobram;Tobi;Nebicina;Tobra;Tobrate;79645-27-5

  • Categories:

    Active Pharmaceutical Ingredients  >  Antibiotics

Description

Tobramycin sulfate (Nebramycin Factor 6 sulfate) is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms[1].

Tobramycin sulfate Basic Attributes

565.59

565.226501

256-499-2

Characteristics

351.15000

-2.36630

1.52g/cm3

775.4ºC at 760mmHg

422.8ºC

2-8°C

Safety Information

3

61-20/21/22

53-22-36/37/39-45

T

|Danger|H312 (98.9%): Harmful in contact with skin [Warning Acute toxicity, dermal]|P201, P202, P261, P271, P280, P281, P302+P352, P304+P312, P304+P340, P308+P313, P312, P322, P363, P405, and P501|Aggregated GHS information provided by 91 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H301 (16.67%): Toxic if swallowed [Danger Acute toxicity, oral]|P201, P202, P260, P261, P263, P264, P270, P271, P280, P281, P301+P310, P301+P312, P302+P352, P304+P312, P304+P340, P308+P313, P311, P312, P314, P321, P322, P330, P361, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 6 companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Tobramycin sulfate Use and Manufacturing

Nebcin (Lilly).

Computed Properties

Molecular Weight:565.6
Hydrogen Bond Donor Count:12
Hydrogen Bond Acceptor Count:18
Rotatable Bond Count:6
Exact Mass:565.22650749
Monoisotopic Mass:565.22650749
Topological Polar Surface Area:351
Heavy Atom Count:37
Complexity:691
Undefined Atom Stereocenter Count:14
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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