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Home > Encyclopedia > 2-AMINO-5-FLUOROBENZALDEHYDE

2-AMINO-5-FLUOROBENZALDEHYDE

2-AMINO-5-FLUOROBENZALDEHYDE structure

2-AMINO-5-FLUOROBENZALDEHYDE 

structure

2-AMINO-5-FLUOROBENZALDEHYDE Basic Attributes

139.13

139.043335

DTXSID40577766

Characteristics

43.1

1.5

1.293

260℃

111℃

1.609

Safety Information

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

2-AMINO-5-FLUOROBENZALDEHYDE Use and Manufacturing

General procedure: Benzyl alcohol derivative 11 (1 eq.) was dissolved in CH2Cl2 (0.4 M). Manganese (IV) oxide (2.1 eq.)was added under argon and the solution was left to stir at room temperature for 48 h. The progress ofthe reaction was monitored by TLC analysis. After completion, manganese oxide was filtered off andthe resulting filtrate was concentrated under reduced pressure. The crude product was purified by silicacolumn chromatography employing mixtures of n-hexane and ethyl acetate as eluents to obtain thedesired product 10.

Computed Properties

Molecular Weight:139.13
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:139.043341977
Monoisotopic Mass:139.043341977
Topological Polar Surface Area:43.1
Heavy Atom Count:10
Complexity:129
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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