2-Chloro-5-fluorobenzaldehyde
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2-Chloro-5-fluorobenzaldehyde
structure -
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CAS No:
84194-30-9
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Formula:
C7H4ClFO
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Chemical Name:
2-Chloro-5-fluorobenzaldehyde
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Synonyms:
2-CHLORO-5-FLUOROBENZALDEHYDE;2-Chloro-5-Flourobenzaldehyde;Benzaldehyde, 2-chloro-5-fluoro-
- Categories:
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CAS No:
Characteristics
17.1
2.1
Colorless liquid
1.4±0.1 g/cm3
46.5-48°C
207.2°C at 760 mmHg
79.1±21.8 °C
1.560
Safety Information
IRRITANT
22-37/38-41
26-39
Xi,Xn
Irritant
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
H315
|Warning|H302 (33.33%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 3 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
2-Chloro-5-fluorobenzaldehyde Use and Manufacturing
The solution of 2-chloro-5-fluoro-benzoic acid (4.00 g, 23.0 mmol) in THE (200 ml) was added triethylamine (4.14 ml, 29.9 mmol). At -30 °C, the mixture was added ethyl chloroformate (2.62 ml, 27.8 mmol) and stirred for 10 min. The solution was added sodium borohydrate (2.60 g, 68.9 mmol) and stirred for 5 min. The mixture was added H25.0 g (0.158 mol, 1.0 eq) of
Computed Properties
Molecular Weight:158.56
XLogP3:2.1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:157.9934706
Monoisotopic Mass:157.9934706
Topological Polar Surface Area:17.1
Heavy Atom Count:10
Complexity:129
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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