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Home > Encyclopedia > 2-Chloro-5-fluorobenzaldehyde

2-Chloro-5-fluorobenzaldehyde

2-Chloro-5-fluorobenzaldehyde structure

2-Chloro-5-fluorobenzaldehyde 

structure
  • CAS No:

    84194-30-9

  • Formula:

    C7H4ClFO

  • Chemical Name:

    2-Chloro-5-fluorobenzaldehyde

  • Synonyms:

    2-CHLORO-5-FLUOROBENZALDEHYDE;2-Chloro-5-Flourobenzaldehyde;Benzaldehyde, 2-chloro-5-fluoro-

  • Categories:

    Organic Chemistry  >  Organic Fluorine Compound

2-Chloro-5-fluorobenzaldehyde Basic Attributes

158.56

157.993469

DTXSID20381308

Characteristics

17.1

2.1

Colorless liquid

1.4±0.1 g/cm3

46.5-48°C

207.2°C at 760 mmHg

79.1±21.8 °C

1.560

Safety Information

IRRITANT

22-37/38-41

26-39

Xi,Xn

Irritant

P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501

H315

|Warning|H302 (33.33%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 3 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

2-Chloro-5-fluorobenzaldehyde Use and Manufacturing

The solution of 2-chloro-5-fluoro-benzoic acid (4.00 g, 23.0 mmol) in THE (200 ml) was added triethylamine (4.14 ml, 29.9 mmol). At -30 °C, the mixture was added ethyl chloroformate (2.62 ml, 27.8 mmol) and stirred for 10 min. The solution was added sodium borohydrate (2.60 g, 68.9 mmol) and stirred for 5 min. The mixture was added H25.0 g (0.158 mol, 1.0 eq) of

Computed Properties

Molecular Weight:158.56
XLogP3:2.1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:157.9934706
Monoisotopic Mass:157.9934706
Topological Polar Surface Area:17.1
Heavy Atom Count:10
Complexity:129
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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