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Home > Encyclopedia > 3-Chloro-2-fluorobenzaldehyde

3-Chloro-2-fluorobenzaldehyde

3-Chloro-2-fluorobenzaldehyde structure

3-Chloro-2-fluorobenzaldehyde 

structure
  • CAS No:

    85070-48-0

  • Formula:

    C7H4ClFO

  • Chemical Name:

    3-Chloro-2-fluorobenzaldehyde

  • Synonyms:

    Benzaldehyde,3-chloro-2-fluoro-;3-Chloro-2-fluorobenzaldehyde;2-Fluoro-3-chlorobenzaldehyde

  • Categories:

    Organic Chemistry  >  Organic Fluorine Compound

Description

lightyellowliqui

3-Chloro-2-fluorobenzaldehyde Basic Attributes

158.56

158.56

5861249

DTXSID80352998

29130000

Characteristics

17.1

2.1

light yellow liquid

1.4±0.1 g/cm3

214 °C(lit.)

186 °F

1.560

Refrigerator

Safety Information

IRRITANT

3

36/37/38-20/21/22

26-36-37/39

Xi,Xn

Irritant

P261-P305 + P351 + P338

H315-H319-H335

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 47 companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

3-Chloro-2-fluorobenzaldehyde Use and Manufacturing

1L four-necked flask, 36.3 g of sodium hydrogencarbonate, 500 g of dichloromethane, 0.5 g of ΤΕΜΡO, and the mixture was cooled to 0 to 5 ° C with stirring, 50 g of 2-fluoro-3-chlorobenzyl alcohol and 100 g of dichloromethane were added dropwise, and then add the sodium hypochlorite solution 230g, drop after the insulation reaction 1 h, sampling control, raw materials ≤ 1percent, stop the reaction, standing stratification, the oil layer of simple distillation of dichloromethane recovery, and then vacuum distillation that 2-fluoro-3-chlorobenzaldehyde 46.1 g, content 97.5percent, yield 91percent.

Computed Properties

Molecular Weight:158.56
XLogP3:2.1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:157.9934706
Monoisotopic Mass:157.9934706
Topological Polar Surface Area:17.1
Heavy Atom Count:10
Complexity:129
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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