Platinum tetrachloride

336.89

334.840210

236-645-1

1145

271964|271963|175496

Brown-red cubic crystals|Brown solid

28439090

0

2.75550

Red-brown Powder

4.3 g/cm³ @ Temp: 25 °C

327 °C (decomp)

H2O: 587 g/L (25 ºC)

Store below +30°C.

Decomposes at 370 °C (698 °F)|Red crystals; loses 4 mol water @ 100 °C; density: 2.43; sol in water and alcohol. /Pentahydrate/

III

8

UN 2923 8/PG 3

3

22-34-42/43

26-27-36/37/39-45-24-22

TP2275500

C

Separated from strong oxidants.

Stable at room temperature in closed containers under normal storage and handling conditions.

P280-P301 + P310-P305 + P351 + P338

H301-H314-H317

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Varies /Platinum (soluble salts as Pt)/

Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.

|Danger|H290 (12.5%): May be corrosive to metals [Warning Corrosive to Metals]|P234, P260, P261, P264, P270, P272, P280, P285, P301+P310, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P304+P341, P305+P351+P338, P310, P321, P330, P333+P313, P342+P311, P363, P390, P404, P405, and P501|Aggregated GHS information provided by 56 companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Employees should be provided with and required to use impervious clothing, face shields (eight-inch minimum), and other appropriate protective clothing necessary to prevent repeated or prolonged skin contact with soluble platinum salts or liquids containing soluble platinum salts, where skin contact may occur. ... Employees should be provided with and required to use dust- and splash-proof safety goggles where soluble platinum salts or liquids containing soluble platinum salts may contact the eyes. /Soluble platinum salts/|Recommendations for respirator selection. Max. concn for use: 4 mg/cu m. Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode. /Platinum (soluble salts as Pt)/|Recommendations for respirator selection. Max. concn for use: 0.1 mg/cu m. Any air-purifying, full-facepiece respirator with a high-efficiency particulate filter.; Any self-contained breathing apparatus with a full facepiece.; Any supplied-air respirator with a full facepiece. /Platinum (soluble salts as Pt)/|Recommendations for respirator selection. Max. concn for use: 0.05 mg/cu m. Any supplied-air respirator operated in a continuous-flow mode. Substance causes eye irritation or damage; eye protection needed. /Platinum (soluble salts as Pt)/|For more Personal Protective Equipment (PPE) (Complete) data for PLATINUM TETRACHLORIDE (6 total), please visit the HSDB record page.

In fire fighting, the minimum respiratory protection required above 0.002 mg/cu m is a self-contained breathing apparatus with a full facepiece operated in pressure-demand or other positive pressure mode. /Soluble platinum salts/

Persons not wearing protective equipment and clothing should be restricted from areas of spills until cleanup has been completed. If soluble platinum salts or liquids containing soluble salts are spilled, the following steps should be taken: 1. Ventilate area of spill; 2. Collect spilled material in the most convenient and safe manner for reclamation or for disposal in a secured sanitary landfill. Liquids containing soluble platinum salts should be absorbed in vermiculite, dry sand, earth, or a similar material, /Soluble platinum salts/

SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.|Eating and smoking should not be permitted in areas where soluble platinum salts or liquids containing soluble platinum salts are handled, processed, or stored. Employees who handle soluble platinum salts or liquids containing soluble platinum salts should wash their hands thoroughly before eating, smoking, or using toilet facilities. /Soluble platinum salts/|Respirators may be used when engineering and work practice controls are not technically feasible, when such controls are in the process of being installed, or when they fail and need to be supplemented. ... If the use of respirators is necessary, the only respirators permitted are those that have been approved by the Mine Safety and Health Admin (formerly Mining Enforcement & Safety Admin) or by the National Institute for Occupational Safety & Health. In addition to respirator selection, a complete respiratory protection program should be instituted which includes regular training, maintenance, inspection, cleaning, and evaluation. /Soluble platinum salts/|Control can only be achieved by preventing the release of the soluble complex platinum salts to the atmosphere of the workshop. Good exhaust ventilation is necessary in platinum refineries. Chemical procedures which may generate these salts should be carried out in ventilated fume cupboards. Open centrifuges should not be used. Good personal hygiene is important. /Platinum compounds/|For more Preventive Measures (Complete) data for PLATINUM TETRACHLORIDE (9 total), please visit the HSDB record page.

A severe skin irritant.|The dusts of soluble platinum salts cause a burning sensation in the eyes, lacrimation, and conjunctival hyperemia, sometimes associated with photophobia, which suggests that the corneal epithelium may be involved. /Soluble platinum salts/|Inhalation of the dust of sol platinum salts is irritating. /Platinum/

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting.

Separated from strong oxidants.

Evaporation at 20 °C is negligible; a harmful concentration of airborne particles can, however, be reached quickly.

The substance is irritating to the eyes, skin and respiratory tract.

PREVENT DISPERSION OF DUST!

Use local exhaust or breathing protection.

Protective gloves.

Wear safety spectacles.

LD50 Rat oral 276 mg/kg|LD50 Rat male oral 240 mg/kg /From table/|LD50 Rat male ip 38 mg/kg /From table/|LD50 Rat male iv 26.2 mg/kg /From table/|LD50 Rat male iv 41.4 mg/kg /From table/

Occupational inhalation allergy (bronchial asthma, rhinitis, conjunctivitis), often in association with urticaria and Quincke edema is common in platinum associated industry. It is due to sensitization against platinum chloride. As an avg of 60% of people working in the platinum industry fall ill with bronchial asthma more stringent protective occupational measures are suggested.

... (191)PtCl4 (25 uCi/animal) /was administered/ intravenously to 15 pregnant rats on day 18 of gestation to determine placental transfer after 24 hr. High levels of (191)Pt radioactivity were found in the kidney (127 064 counts/g) and liver (43 375 counts/g), compared with 10 568 counts/g in the blood. Accumulation was also found in the placenta (27 750 counts/g). (191)Pt was detected in the 60 fetuses examined, but only at very low concentrations (an average of 432 counts/g). Thus, the placental barrier is crossed to a limited extent.

Fresh air, rest. Refer for medical attention.

Remove contaminated clothes. Rinse and then wash skin with water and soap.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Wheezing /in sensitized workers/ can be relieved with bronchodilators and corticosteroids. Complete recovery can be expected if further exposure is avoided. /Chloroplatinates/|Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if needed. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Cover skin burns with dry sterile dressings after decontamination ... . /Poison A and B/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in respiratory arrest. Positive pressure ventilation techniques with a bag valve mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start an IV with D5W /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Poison A and B/

Some workers may show ... allergic manifestations with involvement of the nasal mucosa, bronchi and skin. /Platinum cmpd/

platinum tetrachloride

The substance can be absorbed into the body by inhalation of dust and by ingestion.

Cough. Sore throat.

Redness.

Redness. Pain.

Platinum chloride (PtCl4), (SP-4-1)-: ACTIVE