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Home > Encyclopedia > 2-Carboxyphenylhydrazine hydrochloride

2-Carboxyphenylhydrazine hydrochloride

2-Carboxyphenylhydrazine hydrochloride structure

2-Carboxyphenylhydrazine hydrochloride 

structure
  • CAS No:

    52356-01-1

  • Formula:

    C7H8N2O2.ClH

  • Chemical Name:

    2-Carboxyphenylhydrazine hydrochloride

  • Synonyms:

    Benzoic acid,2-hydrazinyl-,hydrochloride (1:1);Benzoic acid,2-hydrazino-,monohydrochloride;o-Hydrazinobenzoic acid hydrochloride;o-Hydrazinobenzoic acid monohydrochloride;2-Carboxyphenylhydrazine hydrochloride;2-Hydrazinobenzoic acid monohydrochloride;2-Hydrazinylbenzoic acid hydrochloride

  • Categories:

    Organic Chemistry  >  Hydrazine or Hydroxylamine Derivatives

Description

white to light yellow crystal powde

2-Carboxyphenylhydrazine hydrochloride Basic Attributes

188.61

188.035248

4011728

257-869-6

DTXSID9068744

29280090

Characteristics

75.4

2.24570

Off-white to beige Powder

189-190 °C

352.3ºC at 760 mmHg

166.9ºC

2-8°C

Safety Information

IRRITANT

NONH for all modes of transport

3

36/37/38

26-37/39

Xi

Irritant

Stable at room temperature in closed containers under normal storage and handling conditions.

P261-P305 + P351 + P338

H315-H319-H335

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 43 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

2-Carboxyphenylhydrazine hydrochloride Use and Manufacturing

Methods of Manufacturing

Add 6.85g of anthranilic acid and 10ml of water to make a paste, slowly add 12.5ml of concentrated hydrochloric acid, cool to 0°C, add 3.5g of sodium nitrite aqueous solution for diazotization. Then add a solution of 25.5g sodium sulfite in 100ml water below 10°C, stir the reaction, then add glacial acetic acid and zinc powder to stir the reaction and place it at room temperature for 20min, heat in a boiling water bath for 2h, filter, cool the filtrate to room temperature, add concentrated hydrochloric acid to acidify, The precipitate is separated out and filtered to obtain o-hydrazinobenzoic acid hydrochloride.

Uses

Organic synthesis intermediates.

Benzoic acid, 2-hydrazinyl-, hydrochloride (1:1): INACTIVE

Computed Properties

Molecular Weight:188.61
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:188.0352552
Monoisotopic Mass:188.0352552
Topological Polar Surface Area:75.4
Heavy Atom Count:12
Complexity:149
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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