Prosapogenin (Ginseng)
-
Prosapogenin (Ginseng)
structure -
-
CAS No:
50647-08-0
-
Chemical Name:
Prosapogenin (Ginseng)
-
Synonyms:
Prosapogenin (Ginseng);Prosapogenin
- Categories:
-
CAS No:
Description
Ginseng is among the world’s most well-known herbs A number of species of ginseng grow around the wolrd Several species and varieties of ginseng are recognized from different countries The two most commonly used species are P folium L and P ginseng C A Meyer Ginseng has a perennial, fusiform, whitish, thick and feshy root, transversely wrinkled and terminating in fbers The roots mature slowly and are harvested only after the frst 3 years The stem is round, smooth, green, often with a tinge of r
Ginseng is a popular herbal medication and extract derived from the roots of a perennial plant (Panax ginseng) found mostly in China, Korea and Siberia. Ginseng is used is to promote health and improve wellness, as well as to treat stress and as a mild stimulant. Ginseng has not been implicated in causing liver injury although it may have the potential of causing significant herb-drug interactions that can lead to liver injury.
Safety Information
NONH for all modes of transport
3
P264, P280, P302+P352, P305+P351+P338, P310, P321, P332+P313, P337+P313, P362
H315
|Danger|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P264, P280, P302+P352, P305+P351+P338, P310, P321, P332+P313, P337+P313, and P362|Aggregated GHS information provided by 67 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Toxicity
Despite wide spread use, ginseng by itself has not been linked to liver injury, either in the form of transient serum enzyme elevations or clinically apparent acute liver injury. Indeed, ginseng is sometimes used to treat acute or chronic liver injury, although its efficacy and safety in this situation have not been proven. Nevertheless, ginseng has been reported to affect cytochrome P450 activity and cause significant herb-drug interactions that can lead to adverse events including liver injury. In vitro studies have found that different gensinosides have different effects on cytochrome P450 activity, and some may inhibit CYP 3A4 sufficiently to affect the metabolism of other drugs, increasing or decreasing their activity. Thus, different ginseng preparations may exhibit varying degrees of herb-drug interaction. Liver injury has been reported to develop 1 to 3 months after starting ginseng in patients who previously tolerated the potentially toxic agent (imatinib, raltegravir) without liver injury and who later tolerated restarting the medication without concurrent ginseng use.
Drug Information
Ginseng is a popular herbal medication and extract derived from the roots of a perennial plant (Panax ginseng) found mostly in China, Korea and Siberia. Ginseng is used is to promote health and improve wellness, as well as to treat stress and as a mild stimulant. Ginseng has not been implicated in causing liver injury although it may have the potential of causing significant herb-drug interactions that can lead to liver injury.
Herbal and Dietary Supplements
prosapogenin
Prosapogenin (Ginseng) Use and Manufacturing
Cosmetics -> Emollient; Hair conditioning; Skin protecting; Tonic
Computed Properties
Molecular Weight:843.0
XLogP3:0.8
Hydrogen Bond Donor Count:11
Hydrogen Bond Acceptor Count:17
Rotatable Bond Count:9
Exact Mass:842.43000063
Monoisotopic Mass:842.43000063
Topological Polar Surface Area:294
Heavy Atom Count:59
Complexity:1640
Undefined Atom Stereocenter Count:20
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of Prosapogenin (Ginseng)
-
![China]()
CN
3 YRS
Business licensedTrader Supplier of Apigenin,PQQ,NMNHInquiryCAS No.: 50647-08-0Grade: Chemical GradeContent: 99% -
![China]()
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives -
![China]()
CN
5 YRS
Business licensed Certified factoryManufactory Supplier of cosmetic additives,Veterinary APIs,Feed additives,medical and pharmaceutical packaging materials,pharmaceutical equipment,Natural Nutrition Ingredients,intermediates,Food Additives,Medical Devices,Human APIsInquiryCAS No.: 50647-08-0Grade: Food GradeContent: 80%
Learn More Other Chemicals
-
Prosapogenin A
19057-67-1
-
Elastins, cartilage, hydrolyzates
100085-10-7
-
Peptones
73049-73-7
-
Hydrolyzed vegetable protein Formula
100209-45-8
-
Micro-Green Formula
10024-66-5
-
Strontium dichloride hexahydrate Formula
10025-70-4
-
2,5-Pyridinedicarboxylic acid Structure
100-26-5
-
N-Acetyl-α-D-glucosamine Structure
10036-64-3
-
What is Ceramides
100403-19-8
-
What is 1-Methylnicotinamide chloride
1005-24-9