BOC-D-LEUCINOL97

(1) Di-tert-butyl dicarbonate (4.1 g) was added to a solution of 2-amino-4-methylpentan-1-ol (2.0 g) in THF (40 mL), and the mixture was stirred at room temperature overnight. The reaction mixture was concentrated under reduced pressure, and the residue was washed with a mixed solvent of hexane/ethyl acetate (=5:1) to afford tert-butyl (1-hydroxy-4-methylpentan-2-yl)carbamate (3.7 g). (ESI pos.) m/z: 240 ([M+Na]+)(1) Di-tert-butyl dicarbonate (4.1 g) was added to a solution of 2-amino-4-methylpentan-1-ol (2.0 g) in THF (40 mL), and the mixture was stirred at room temperature overnight. The reaction mixture was concentrated under reduced pressure, and the residue was washed with a mixed solvent of hexane/ethyl acetate (=5:1) to afford tert-butyl (1-hydroxy-4-methylpentan-2-yl)carbamate (3.7 g). (ESI pos.) m/z: 240 ([M+Na]+)

Molecular Weight:217.31
XLogP3:2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:217.16779360
Monoisotopic Mass:217.16779360
Topological Polar Surface Area:58.6
Heavy Atom Count:15
Complexity:197
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes