α-Lactose monohydrate
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α-Lactose monohydrate
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CAS No:
5989-81-1
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Formula:
C12H22O11.H2O
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Chemical Name:
α-Lactose monohydrate
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Synonyms:
α-D-Glucopyranose,4-O-β-D-galactopyranosyl-,hydrate (1:1);Lactose,monohydrate,α-;α-D-Glucopyranose,4-O-β-D-galactopyranosyl-,monohydrate;α-Lactose monohydrate;α-D-Lactose monohydrate;4-O-β-D-Galactopyranosyl-α-D-glucopyranose monohydrate;Zeparox;Pharmatose DCL 11;Pharmatose 50M;GranuLac 200;Lactose D 80;Pharmatose 90M;Granulac 230;Lactose 100M;Pharmatose 150M;Aeroflo 95;Aeroflo 65;Aeroflo 20;Inhalac 120;Inhalac 230;Pharmatose 325;Flowlac 200;Lactosum D 80;Lactochem;InhaLac 400;96231-95-7;60004-41-3
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CAS No:
Description
White powder Lactose occurs as white to off-white crystalline particles or powder. It is odorless and slightly sweet-tasting. Spray-dried directcompression grades of lactose are generally composed of 80–90% specially prepared pure a-lactose monohydrate along with 10–20% of amorphous lactose.
α-Lactose monohydrate Basic Attributes
360.31
360.126770
200-559-2
EWQ57Q8I5X
DTXSID2051421|DTXSID1052828
17021100
Characteristics
191
-5.46150
White powder
1.53 g/cm3
201-202 °C
667.931°C at 760 mmHg
357.8ºC
1.652
soluble in water.H2O: soluble 1M, clear, colorless
Store in air tight containers.
176.8 Ų [M-H]-
α-Lactose monohydrate Use and Manufacturing
The characteristics of nitrolactose separation in GLC: a disaccharide separated from the milk of mammals. About 4%-5% in cow~"s milk and about 6.7% in human milk. Acidic hydrolysis yields equal molecules of D-glucose and D-galactose. It is a reducing sugar that can reduce the Fehling solution. Crystallization in normal temperature aqueous solution yields α-lactose, and crystallization above 93°C yields β-lactose. Alpha lactose is common lactose. It has a weak sweet taste, usually with a molecule of crystal water. It is a monoclinic crystal. At 120°C, the crystal water is lost and heated rapidly. The aqueous solution has a spin phenomenon, [a]20D-92.6°→+83.5°(10 minutes)→+69°(50 minutes)→+52.3°(22 hours). β-lactose is slightly sweeter than α-lactose. White crystals. Melting point 252℃. The aqueous solution also has a phenomenon of spin. [α]25D +34° (3 minutes) → +39° (6 minutes) → +46° (1 hour) → 52.3° (22 hours). β-lactose can be transformed into α-lactose after absorbing water at normal temperature, and the latter becomes β-lactose when heated to above 93℃. The xylene and xylene isomers are components of the liquid-solid phase.
Computed Properties
Molecular Weight:360.31
Hydrogen Bond Donor Count:9
Hydrogen Bond Acceptor Count:12
Rotatable Bond Count:4
Exact Mass:360.12677620
Monoisotopic Mass:360.12677620
Topological Polar Surface Area:191
Heavy Atom Count:24
Complexity:382
Defined Atom Stereocenter Count:10
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
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