Cytidine 5′-(tetrahydrogen triphosphate), sodium salt (1:2)
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Cytidine 5′-(tetrahydrogen triphosphate), sodium salt (1:2)
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CAS No:
36051-68-0
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Formula:
C9H16N3O14P3.2Na
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Chemical Name:
Cytidine 5′-(tetrahydrogen triphosphate), sodium salt (1:2)
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Synonyms:
Cytidine 5′-(tetrahydrogen triphosphate),sodium salt (1:2);Cytidine 5′-(tetrahydrogen triphosphate),disodium salt;Cytidine-5′-triphosphate disodium salt;NSC 20261;Cytidine triphosphate disodium salt;Disodium cytidine triphosphate
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CAS No:
Cytidine 5′-(tetrahydrogen triphosphate), sodium salt (1:2) Basic Attributes
527.12
526.948425
252-849-3
20261
29349990
Characteristics
305.51000
-0.75440
White Powder
2.5g/cm3
849.2°C at 760 mmHg
113 °C
soluble in water. Insoluble in ethanol, chloroform and ether.H2O: 50 mg/mL, clear, colorless
−20°C
Cytidine 5′-(tetrahydrogen triphosphate), sodium salt (1:2) Use and Manufacturing
Cytidine 5'-triphosphate (CTP) is a pyrimidine nucleoside triphosphate that is involved in a variety of biochemical reactions. It is used in the synthesis of RNA by RNA polymerases. In the formation of phosphatidylcholine (PC), CTP reacts with phosphocholine, via CTP:phosphocholine cytidylyltransferases, to produce CDP-choline and diphosphate. This is the rate-limiting step in PC synthesis and, as a pivotal step in cell proliferation, can be important in cancer. CTP also interacts with N-acylneuraminate, in a reaction mediated by N-acylneuraminate cytidylyltransferase, to generate an intermediate that is required for sialylation, namely CMP-N-acylneuraminic acid.[Cayman Chemical]
Computed Properties
Molecular Weight:483.16
XLogP3:-5.6
Hydrogen Bond Donor Count:7
Hydrogen Bond Acceptor Count:14
Rotatable Bond Count:8
Exact Mass:482.98451319
Monoisotopic Mass:482.98451319
Topological Polar Surface Area:268
Heavy Atom Count:29
Complexity:855
Undefined Atom Stereocenter Count:4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Drug Function and Efficacy
Coenzyme drugs are nucleotide derivatives that participate in the synthesis and metabolism of phospholipids and nucleic acids in the body. They are intermediate products and energy sources for brain phospholipid synthesis and nucleic acid metabolism.
Registered Holders
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Hangzhou Meiya Pharmaceutical Co., Ltd.
Active
China
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Jiuquan Dadeli Pharmaceutical Co., Ltd.
Active
China
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Hainan Lingkang Pharmaceutical Co., Ltd.
Active
China
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