Panobinostat
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Panobinostat
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CAS No:
404950-80-7
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Formula:
C21H23N3O2
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Chemical Name:
Panobinostat
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Synonyms:
2-Propenamide,N-hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-,(2E)-;(2E)-N-Hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide;Panobinostat;LBH 589;Farydak;NVP-LBH 589;NVP LBH 589;944726-21-0
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CAS No:
Characteristics
77.2
3
Yellow solid
1.2±0.1 g/cm3
114-117°C
1.683
-20°C Freezer, Under Inert Atmosphere
Safety Information
22-36/37/38-20
24/25
P201, P202, P260, P261, P264, P270, P271, P280, P281, P301+P310, P302+P352, P304+P340, P305+P351+P338, P308+P313, P310, P311, P314, P321, P330, P332+P313, P362, P403+P233, P405, P501
H301+H331
Panobinostat Use and Manufacturing
The novel histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and apoptosis in Ph- acute lymphoblastic leukemia cells.
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