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Thiazovivin

Thiazovivin structure

CAS No:
1226056-71-8
Formula:
C15H13N5OS
Chemical Name:
Thiazovivin
Synonyms:
N-Benzyl-2-(pyrimidin-4-ylamino)thiazole-4-carboxamide;Thiazovivin;N-(Phenylmethyl)-2-(4-pyrimidinylamino)-4-thiazolecarboxamide;N-(Phenylmethyl)-2-(4-pyrimidinylamino)-4-thiazolecarboxamideThiazovivin;Thiazovivin N-(Phenylmethyl)-2-(4-pyrimidinylamino)-4-thiazolecarboxamide;Thiazovivin, >=98%;N-Benzyl-2-(4-pyrimidinylamino)-1,3-thiazole-4-carboxamide
Categories:
Biochemical Engineering > Inhibitors

Description

Thiazovivin is a novel ROCK inhibitor with IC50 of 0.5 μM in a cell-free assay, promotes hESC survival after single-cell dissociation.

Thiazovivin Basic Attributes

Molecular Weight：

311.36162

Exact Mass：

311.084076

EC Number：

1312995-182-4

HScode：

2934100090

Characteristics

PSA：

108

XLogP3：

2.5

Appearance：

white to beige to brown

Density：

1.379

Refractive Index：

1.691

Water Solubility：

DMSO: soluble20mg/mL, clear

Storage Conditions：

Store at -20°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

Marks：

Precautionary statement(s)：

P264, P270, P301+P312, P330, P501

Hazard Statements：

H302

Thiazovivin Use and Manufacturing

A compound that improves the survival of human embryonic stem cells (hESCs) upon trypsinization. In combination with ALK5 (TGFβ receptor) inhibitor SB-431542 and MEK inhibitor PD-0325901 (P217450), Thiazovivin promotes the transformation of fibroblasts into stem cells with a 200-fold efficiency over the classic method

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CAS No.: 1226056-71-8

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Thiazovivin

CAS No.: 1226056-71-8

Content: 99%

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