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SR2516

SR2516 structure

CAS No:
1061353-68-1
Formula:
C25H26F3N5O3
Chemical Name:
SR2516
Synonyms:
PND 1186;PND1186;PND-1186;SR 2516;SR2516;SR-2516;VS-4718;PND-1186 (VS-4718)
Categories:
Biochemical Engineering > Inhibitors

Description

VS-4718 is under investigation in clinical trial NCT02215629 (Dose Escalation Study in Acute Myeloid or B-Cell Acute Lymphoblastic Leukemia).

SR2516 Basic Attributes

Molecular Weight：

501.5008496

Exact Mass：

501.199

UNII：

L2BD0MW4OL

Characteristics

PSA：

87.8

XLogP3：

4.7

Density：

1.334±0.06 g/cm3(Predicted)

Boiling Point：

654.0±55.0 °C(Predicted)

Drug Information

MeSH Entry Terms：

PND 1186

SR2516 Use and Manufacturing

2- { [2-Chloro-5 -(trifluoromethyl)-4-pyridinyl] amino } -N-methylbenzamide (Intermediate 1 , 50 mg, 0.152 mmol) and [2-(methyloxy)-4-(4-morpholinyl)phenyl]amine (148 mg, 0.607 mmol) were combined with IM hydrochloric acid (0.303 mL, 0.303 mmol), 1, 4- 2- { [2-Chloro-5 -(trifluoromethyl)-4-pyridinyl] amino } -N-methylbenzamide (Intermediate 1 , 50 mg, 0.152 mmol) and [2-(methyloxy)-4-(4-morpholinyl)phenyl]amine (148 mg, 0.607 mmol) were combined with IM hydrochloric acid (0.303 mL, 0.303 mmol), 1, 4-

Computed Properties

Molecular Weight:501.5
XLogP3:4.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:7
Exact Mass:501.19877419
Monoisotopic Mass:501.19877419
Topological Polar Surface Area:87.8
Heavy Atom Count:36
Complexity:709
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of SR2516

Anqing Rongchuang Biotechnology Co., Ltd Contact Supplier

CN
1 YR

Business licensed Certified factory

Manufactory Supplier of SR17018

PND-1186,SR-2156

CAS No.: 1061353-68-1

Content: 98%

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