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3-(1-Methyl-4-piperidinyl)-1H-indol-5-ol

3-(1-Methyl-4-piperidinyl)-1H-indol-5-ol structure

CAS No:
57477-39-1
Formula:
C14H18N2O
Chemical Name:
3-(1-Methyl-4-piperidinyl)-1H-indol-5-ol
Synonyms:
1H-Indol-5-ol,3-(1-methyl-4-piperidinyl)-;3-(1-Methyl-4-piperidinyl)-1H-indol-5-ol;BRL 54443
Categories:
Biochemical Engineering > Inhibitors

Description

BRL 54443 is a potent 5-HT1E/1F receptor agonist (pKi values are 8.7 and 8.9 respectively); displays > 30-fold selectivity over other 5-HT and dopamine receptors.IC50 value: 8.7(pKi, 5-HT1E); 8.9 (pKi, 5-HT1F) Target: 5-HT1E/1F receptorin vitro: BRL 54443 is a potent 5-ht1E/1F receptor agonist (pEC50 values are 8.5 and 8.6 respectively). Displays > 30-fold selectivity over other 5-HT and dopamine receptors (pKi values are 8.7. 8.9, 7.2, 6.9, 7.2, 5.9, 7.0, 6.5, < 6, < 6, 6.3 and 6.2 for

3-(1-methyl-4-piperidinyl)-1H-indol-5-ol is a member of hydroxyindoles.

3-(1-Methyl-4-piperidinyl)-1H-indol-5-ol Basic Attributes

Molecular Weight：

230.31

Exact Mass：

230.31

UNII：

Q2DH1CHI0Y

DSSTox ID：

DTXSID40206089

HScode：

2933990090

Characteristics

PSA：

39.3

XLogP3：

1.5

Appearance：

white solid

Density：

1.2±0.1 g/cm3

Flash Point：

214.8±28.7 °C

Refractive Index：

1.646

Water Solubility：

H2O: 50 mg/mL

Storage Conditions：

2-8°C

Safety Information

wgk germany：

hazard class code：

36/37/38

safety instructions：

26-36

Marks：

Computed Properties

Molecular Weight:230.31
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:230.141913202
Monoisotopic Mass:230.141913202
Topological Polar Surface Area:39.3
Heavy Atom Count:17
Complexity:263
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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3-(1-Methyl-4-piperidinyl)-1H-indol-5-ol

CAS No.: 57477-39-1

Content: 99.00%

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Guide of 3-(1-Methyl-4-piperidinyl)-1H-indol-5-ol

Description
Basic Attributes
Characteristics
Safety Information
Computed Properties
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