 Home > Encyclopedia > PIK-293

PIK-293

PIK-293 structure

CAS No:
900185-01-5
Formula:
C22H19N7O
Chemical Name:
PIK-293
Synonyms:
PIK-293;2-[(4-Amino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone;2-((4-amino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one
Categories:
Biochemical Engineering > Inhibitors

Description

PIK-293, an analog of IC87114, is a PI3K inhibitor, with IC50 values of 0.24 μM, 10 μM, 25 μM and 100 μM for p110δ, p110β, p110γ and p110α, respectively[1].

PIK-293 Basic Attributes

Molecular Weight：

397.442

Exact Mass：

397.165100

EC Number：

-0

DSSTox ID：

DTXSID40692887

Characteristics

PSA：

102

XLogP3：

2.18

Density：

1.4±0.1 g/cm3

Boiling Point：

657.3±65.0 °C at 760 mmHg

Flash Point：

351.3±34.3 °C

Refractive Index：

1.759

Computed Properties

Molecular Weight:397.4
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:397.16510826
Monoisotopic Mass:397.16510826
Topological Polar Surface Area:102
Heavy Atom Count:30
Complexity:684
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of PIK-293

HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

PIK-293

CAS No.: 900185-01-5

Content: 99.00%

Inquiry
Creative Enzymes Contact Supplier

US
6 YRS

Business licensed Certified factory

Manufactory Supplier of Coenzymes,Inhibito,Enzymes,Zymogens,Substrates

PIK-293

CAS No.: 900185-01-5

Content: 99%

Inquiry