Indacaterol maleate
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Indacaterol maleate
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CAS No:
753498-25-8
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Formula:
C24H28N2O3.C4H4O4
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Chemical Name:
Indacaterol maleate
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Synonyms:
2(1H)-Quinolinone,5-[(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-,(2Z)-2-butenedioate (1:1);2(1H)-Quinolinone,5-[(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-,(2Z)-2-butenedioate (1:1) (salt);Indacaterol maleate;QAB 149AFA;Onbrez;Arcapta;Oslif Breezhaler;Onbrez Breezhaler;Hirobriz Breezhaler;435273-74-8
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CAS No:
Description
Indacaterol Maleate is an ultra-long-acting β-adrenoceptor agonist.Target: β-adrenoceptorIndacaterol inhibits cAMP production in Chinese hamster ovary cells stably transfected with human β2 adrenoceptors with pEC50 of 8.06. Indacaterol inhibits electrically induced contraction on the electrically stimulated guinea pig trachea in a concentration-dependent manner with pEC50 of 8.23. Indacaterol induces a concentration-dependent inotropic effect with maximal efficacy of 75% in the isolated
Indacaterol maleate Use and Manufacturing
A long-acting β2 adrenoreceptor agonist and bronchodilator, for the treatment of asthma and chronic obstructive pulmonary disease.
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