Zotarolimus
-
Zotarolimus
structure -
-
CAS No:
221877-54-9
-
Formula:
C52H79N5O12
-
Chemical Name:
Zotarolimus
-
Synonyms:
Rapamycin,42-deoxy-42-(1H-tetrazol-1-yl)-,(42S)-;(42S)-42-Deoxy-42-(1H-tetrazol-1-yl)rapamycin;A 179578;ABT 578;Zotarolimus;42-(1-Tetrazolyl)rapamycin;Resolute;Endeavor;916135-04-1
- Categories:
-
CAS No:
Description
Zotarolimus is a tetrazole-containing Rapamycin analog which is used as animmunomodulator, and is useful in the treatment of restenosis, immune, and autoimmune diseases.
Zotarolimus is a macrolide and a lactam.
Characteristics
218.80000
3.55
1.3±0.1 g/cm3
100-105°C
1016.2±75.0 °C at 760 mmHg
568.4±37.1 °C
1.586
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Zotarolimus Use and Manufacturing
A tetrazole-containing Rapamycin analog as immunomodulator and useful in the treatment of restenosis and immune and autoimmune diseases.
Computed Properties
Molecular Weight:966.2
XLogP3:5.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:15
Rotatable Bond Count:7
Exact Mass:965.57252297
Monoisotopic Mass:965.57252297
Topological Polar Surface Area:219
Heavy Atom Count:69
Complexity:1890
Defined Atom Stereocenter Count:15
Defined Bond Stereocenter Count:4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of Zotarolimus
-
![China]()
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives -
![China]()
CN
3 YRS
Business licensed Certified factoryManufactory Supplier of Chemical,Intermediate,5-amino-1mq,SLU-PP332,Tirzepatide,Peptide,KY19382,5-deazaflavin,Dihexa,Urolithin AInquiryUnit Price: $1700-2000 /G FOBCAS No.: 221877-54-9Grade: Pharmaceutical GradeContent: 99%
Latest News on Zotarolimus
- BMS Over $900 Million to Help Develop Potential 'Best-in-class' SHP2 Inhibitors
- AbbVie's blockbuster product for atopic dermatitis, Upadacitinib, has been approved for marketing in the EU and Japan
- Designing peptide inhibitors for possible COVID-19 treatments
- Chinese scientists discover the inhibitors of SARS-CoV-2
Learn More Other Chemicals
-
Dabrafenib
1195765-45-7
-
BOC-VAL-VAL-OH
69209-73-0
-
BMS 303141
943962-47-8
-
(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanamide Formula
60117-17-1
-
(2S)-2-acetamido-6-amino-N-[(2S)-2-amino-3-methylbutanoyl]-N-propylhexanamide Formula
57899-96-4
-
1-(6-methoxy-1,3-benzothiazol-2-yl)-3-phenylurea Formula
26130-02-9
-
L-Tyrosyl-L-phenylalanine Structure
17355-11-2
-
C-REACTIVE PROTEIN FRAGMENT 77-82 Structure
130349-01-8
-
What is Sildenafil
139755-83-2
-
What is Dacomitinib
1110813-31-4