N-(2,3-Dihydro-7,8-dimethoxyimidazo[1,2-c]quinazolin-5-yl)-3-pyridinecarboxamide
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![N-(2,3-Dihydro-7,8-dimethoxyimidazo[1,2-c]quinazolin-5-yl)-3-pyridinecarboxamide structure](https://file.echemi.com/fileManage/upload/canonicalSmiles/20220811/b167d40650344d9c8d173a831bdfd48c.png "N-(2,3-Dihydro-7,8-dimethoxyimidazo[1,2-c]quinazolin-5-yl)-3-pyridinecarboxamide")
N-(2,3-Dihydro-7,8-dimethoxyimidazo[1,2-c]quinazolin-5-yl)-3-pyridinecarboxamide
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CAS No:
677338-12-4
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Formula:
C18H17N5O3
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Chemical Name:
N-(2,3-Dihydro-7,8-dimethoxyimidazo[1,2-c]quinazolin-5-yl)-3-pyridinecarboxamide
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Synonyms:
N-(2,3-Dihydro-7,8-dimethoxyimidazo[1,2-c]quinazolin-5-yl)-3-pyridinecarboxamide;PIK 90;PIK90(PIK-90);N-(2,3-Dihydro-7,8-dimethoxyimidazo[1,2-c]quinazolin-5-yl)-3-pyridinecarboxamidePIK-90;PIK 90 N-(2,3-Dihydro-7,8-dimethoxyimidazo[1,2-c]quinazolin-5-yl)-3-pyridinecarboxamide;N-(7,8-Dimethoxy-2,3-dihydroimidazo-[1,2-c]quinazolin-5-yl)nicotinamide;N-(2,3-Dihydro-7,8-dimethoxyimidazo[1,2-c]quizolin-5-yl)-3-pyridinecarboxamide
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CAS No:
Description
PIK-90 is a DNA-PK and PI3K inhibitor, which inhibits p110α, p110γ and DNA-PK with IC50s of 11, 18 and 13 nM, respectively.
N-(7,8-dimethoxy-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)-3-pyridinecarboxamide is a member of quinazolines.
N-(2,3-Dihydro-7,8-dimethoxyimidazo[1,2-c]quinazolin-5-yl)-3-pyridinecarboxamide Basic Attributes
351.364
351.133
DTXSID40425899
Computed Properties
Molecular Weight:351.4
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:351.13313942
Monoisotopic Mass:351.13313942
Topological Polar Surface Area:88.4
Heavy Atom Count:26
Complexity:778
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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N-(2,3-Dihydro-7,8-dimethoxyimidazo[1,2-c]quinazolin-5-yl)-3-pyridinecarboxamide
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